Pairwise Alignments

Query, 1298 a.a., phosphoribosylformylglycinamidine synthase, single chain form from Pseudomonas stutzeri RCH2

Subject, 989 a.a., AIR synthase related protein from Methanococcus maripaludis S2

 Score =  149 bits (376), Expect = 1e-39
 Identities = 187/764 (24%), Positives = 309/764 (40%), Gaps = 68/764 (8%)

Query: 178 LALAEDEIDYLVSAFQGLKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGESQDKSLFG 237
           LAL  D I  +   +Q   RNP DIEL   AQ  SEHC+H IF +  D   E   K    
Sbjct: 214 LALDLDYITAIKEYYQKEGRNPTDIELEALAQTWSEHCKHTIFASQIDDIEEGIFKKYIR 273

Query: 238 MIKNTYQMH---SENVLSAYKDNASVIVGHTAGRFFPNPETRQYGAVQEPVHILMKVETH 294
              N  +      +  +S + DN+  I+                    +   +  K ETH
Sbjct: 274 NATNEIREELGEKDFCISVFSDNSGGII------------------FDDEWMVTDKAETH 315

Query: 295 NHPTAISPFSGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLNIPGFEQPWEQAYGKP 354
           N P+A+ PF GA TG  G  RD    G GA P A   GF V     P   +   +   K 
Sbjct: 316 NSPSALDPFGGAITGIVGVNRDTVGFGLGALPVANKYGFCVGR---PEDTEIIYRGQNKT 372

Query: 355 ERIVTPLDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSISTPRGDEVRGYHKPIMLAGG 414
              + P  I+     G     N+ G P   G F  F+        D  +G  KP++  G 
Sbjct: 373 NPSLLPRRILDGIVHGVNVGGNQSGIPTPNG-FVYFD--------DTYKG--KPLVFVGT 421

Query: 415 LGNI-------REDHVQKAEITVGAKLIVLGGPAMLIGLGGGAASSVATGASSADLDFAS 467
           +G I       R  H + AE   G  ++++GG     G+ G   SS A    S     A+
Sbjct: 422 IGLIPRKLPDGRLSHEKAAE--NGDNIVIIGGRVGKDGIHGATFSSEAMDEGS---PAAA 476

Query: 468 VQRENPEMERRCQEVIDRCWQLGDQNPIAFIHDVGAGGISNAFPELVNDGGRGGRFELRN 527
           VQ  +P  +++  + + +  +  D+     I D GAGGIS +  E+  + G G   EL  
Sbjct: 477 VQIGDPITQKKLSDAVIK--EARDKGLYNSITDNGAGGISCSVAEMAEECG-GFVVELEE 533

Query: 528 VPNDEPGMAPHEIWSNESQERYVLAVSTVDFERFQAICERERCPFAVVGEATEEPQLTVT 587
           VP   PG+ P EIW +ESQER  L+V     E F  + +       V+G+     +  V 
Sbjct: 534 VPLKYPGLEPWEIWISESQERVTLSVPDDKLEEFMDLMKIRGVEAVVIGKFNNTDRAVV- 592

Query: 588 DSHFGNTPVDMPLEVLLGKPPRMHRSASREAELGDDFDAAAVDLSEAVTRVLRHPAVASK 647
            ++ G T +D+ ++ L    P+        +   ++ +    +  E   ++L +    S 
Sbjct: 593 -NYNGKTIMDLEMDFLHNGLPKRKLITKPYSYRTEEPEITVENQLETFEKILGNHNNCSF 651

Query: 648 SFLITIGDRSITGQVARDQMVGPWQVPVADCAVTATSYDVYTGEAMAMGERTPLALLDAP 707
            ++    D  +        + G  +V     +V         G  M+      L+ +   
Sbjct: 652 EYISKQYDHEVQNNSVIKPLQGKGRVN-GTASVIRPLLSSQKGLVMSQSLLPRLSEISCY 710

Query: 708 ASGRMAIGETLTNLAAARIEKISDIKLSANWMAAAGHPGEDARLYETVRAVGMELCPQLG 767
                A+   + N  A     I+ I +  N+   +    E  RLY+   A   + C    
Sbjct: 711 DMAACAMDTAIRNCVAVG-GNINHIAIMDNFCWCSS--DEPERLYQLKDAA--KSCYDYA 765

Query: 768 LT----IPVGKDSMSMKTR-WSEEGAEKSVTSPMSLIVSGFAPVTDVRQTLTPQLRLDKG 822
            T    +  GKDSM    + + E      ++   +L++S    + ++  T +  L+L   
Sbjct: 766 KTYLTPLISGKDSMFNDFKGFDENNNPIKISVHPTLMMSALGVIDNIEHTNSMDLKL--- 822

Query: 823 ATDLILIDLGRGQNRMGASILAQVYGQLGRQAPDVDDAEDLQAFFAVVQGLNADGLLLAY 882
             DLI + +G  ++  G S     +G++G  +P V DA+  +  +  +  L+  G+  + 
Sbjct: 823 KDDLIYV-IGETKDECGGSEFYHAFGEVGGISPKV-DAKSARKLYEKMYELSQKGIFSSC 880

Query: 883 HDRSDGGLLTTVLEMAFAGHCGLSLNLDGLLESAVDVAPMLFNE 926
              + GGL+ T+ +MA +G  GL  +L       +    ++++E
Sbjct: 881 ASVAAGGLVITLAKMAISGCLGLEADLSKAPNENISFEKIMYSE 924



 Score = 32.0 bits (71), Expect = 3e-04
 Identities = 21/118 (17%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 465 FASVQRENPEMERR-CQEVIDRCWQLGDQNPIAFIHDVGAGGISNAFPELVNDGGRGGRF 523
           F  V   +P+++ +  +++ ++ ++L  +   +    V AGG+     ++   G  G   
Sbjct: 846 FGEVGGISPKVDAKSARKLYEKMYELSQKGIFSSCASVAAGGLVITLAKMAISGCLGLEA 905

Query: 524 ELRNVPNDEPGMAPHEIWSNESQERYVLAVSTVDFERFQAICERERCPFAVVGEATEE 581
           +L   PN+   ++  +I  +E+Q R+++ ++  + + F+ + +  +     +G  TE+
Sbjct: 906 DLSKAPNE--NISFEKIMYSETQSRFIVTIAPENEKEFENLMKEFK--IGKIGNVTEK 959