Pairwise Alignments

Query, 434 a.a., folylpolyglutamate synthase/dihydrofolate synthase from Pseudomonas stutzeri RCH2

Subject, 421 a.a., bifunctional tetrahydrofolate synthase/dihydrofolate synthase from Vibrio cholerae E7946 ATCC 55056

 Score =  310 bits (794), Expect = 5e-89
 Identities = 176/422 (41%), Positives = 251/422 (59%), Gaps = 14/422 (3%)

Query: 6   LADWLAYLEQLHPTAIDMGLDRVRLVSARLGLTRSAPLAVTVTGTNGKGSTCAFIASLLN 65
           LA WL YL  +H +AID+GL+RV+ V+ +  LT+ AP  +TV GTNGKGSTCA + ++L 
Sbjct: 13  LAVWLDYLAHIHTSAIDLGLERVQAVAQKAKLTKPAPTVITVAGTNGKGSTCALMEAILL 72

Query: 66  SQGMRVGTYSSPHLLRYNERVQLDGCEASDQELCEAFAAVEAARGEVSLTYFEMGTLAAF 125
             G  VG YSSPHL+RYNERV+++G + +D+   +AFA +E  RG++SL+ FE GTLAA 
Sbjct: 73  QAGYSVGVYSSPHLIRYNERVRINGQDLADEMHTQAFAHIEQERGDISLSLFEFGTLAAL 132

Query: 126 WLFERAELDAAVLEVGLGGRLDAVNIVDADLAVITNIGLDHADWLGDTRESVAYEKAGIM 185
           +LFE+ ++D  +LEVGLGGRLDA N+VD D++VIT++ LDH DWLG+    + YEKAGI 
Sbjct: 133 YLFEQQKVDVLLLEVGLGGRLDATNVVDHDVSVITSLALDHTDWLGNDIAVIGYEKAGIF 192

Query: 186 RAGKPVLCGDLDVPAPLLQQAESLKAPLLLRGRDFDL-AFAPRAWHWRGVGPAGEPLELH 244
           R+GKP +CG    PA +   A+ + A L      F     +   W+WR         EL 
Sbjct: 193 RSGKPAICGQPKPPATVAAHADDIGAKLHQVEIQFSYEKTSATTWNWR-----SGRFELT 247

Query: 245 GLPLLSLPMENAAIALQAYASLGLPWDVKVLSAALEQTRVTGRLDRRQITWRGRKVSLLL 304
            LP+ SLP+ NAA AL A    GL      +   L   ++ GR+   Q+     + +++L
Sbjct: 248 DLPIPSLPLPNAATALMALGCSGLAISDINIVDGLRNAQLAGRM---QVI--SHQPTIVL 302

Query: 305 DVGHNPHAASYLAQRIEQRPIAGRRLAVFGLLADKDLDGVLDAVQASITDWAVAPLPTSR 364
           DV HNPH+A YL Q++ QR        VFG+L DKD+   +  +  ++T W  A L   R
Sbjct: 303 DVAHNPHSAHYLVQQLTQRYPERTIHLVFGMLHDKDIASTVVELSPAVTHWYPASLSGPR 362

Query: 365 TQSATQLSAALLERGALVGEYASIEQALDAQCAKAEPDDEVLVFGSFYCVAAALGWLERQ 424
             +A QL   L    A + +YA+   A +A   +A   D ++V GSF+ V   L   +++
Sbjct: 363 AATAAQLCQYL---PADITQYANPVSAFEAALTQAGAQDVIVVAGSFHTVGEVLEHWQKR 419

Query: 425 AE 426
            E
Sbjct: 420 GE 421