Pairwise Alignments

Query, 527 a.a., signal transduction histidine-protein kinase/phosphatase UhpB from Vibrio cholerae E7946 ATCC 55056

Subject, 500 a.a., two-component system sensor histidine kinase UhpB from Klebsiella michiganensis M5al

 Score =  281 bits (719), Expect = 4e-80
 Identities = 183/526 (34%), Positives = 290/526 (55%), Gaps = 46/526 (8%)

Query: 2   AKLFPLIFAFVLYSISQFSLWNVSQYLSHNPLQAYLLFPTGLRLAVYLLARPTYVW---- 57
           ++L  ++    ++S + F LW++S +L   P  A LLFP GLRL + +L  P   W    
Sbjct: 6   SRLLSVVGCCFIFSAAWFCLWSISLHLVERPDLAVLLFPFGLRLGL-MLQCPRGYWPVLL 64

Query: 58  -------VWLLSDMLLAGVILVLLPDQSSPLMLLMPWVVWLAAVIARQHWPKLHLYWQKL 110
                  +WL  ++ LA  I+++    +  L+ L+P      A+I+R    +    W  L
Sbjct: 65  GAEWLLILWLAQEVALAHPIILM----TGSLLTLLP-----VALISRYRQQR---DWLTL 112

Query: 111 LLIVALVLLHTILVGITFTLLAKPLHMGAETLIAVSIASLTGGIVLTPFLYLVADYLSHQ 170
           L     ++   +L  + + L       G E L A+ + +LTGG+ L P   ++  YL+  
Sbjct: 113 LRQGGALIAAALLQSLPWLL------EGKEGLNAL-LLTLTGGLTLAPTCLVIWHYLTST 165

Query: 171 TWHPLSPQLIHHDVKLKPKMLMWSLLFFSLGLLAELTLLEQMKPFALLIILLPTIFLAYR 230
            W PL P L+   V  + + L+W LL FS+ L  +L L  ++  F    + LP I LA+ 
Sbjct: 166 VWRPLGPSLVSQPVNWRGRHLIWYLLLFSVSLWLQLGLPAELSRFTPFCLALPIIALAWH 225

Query: 231 YGWQGGVLASSLNCILLATARQFSGSFSSDQELLIFMSSQAFVGLGLGIAISRQHQLALL 290
           YGWQG ++A+ +N I L  ++ +        +LL+ + +Q+  GL LG  I R       
Sbjct: 226 YGWQGALIATLMNAIALIASQTW---HDHPVDLLLSLLAQSLTGLLLGAGIQR------- 275

Query: 291 LQKMNTRLAKELREKQDLARQLVSVEEQIRKSVARELHDEIGQNITAIQIQSMLAERLAS 350
           L+++N  L KEL   Q LA +L+  EE +R+ VARELHD+IGQ ITAI+ Q+ + +RLA 
Sbjct: 276 LRELNQSLQKELVRNQRLAERLLETEESVRREVARELHDDIGQTITAIRTQAGIVQRLAP 335

Query: 351 ND-QAKQAASSVQSLAMRIHQSTRQLLKQLRPHILDELGLEHAIRQLVQEMRFAEQGMTV 409
           N    +Q+   ++ L++ ++ S R+LL +LRP  LD+L LE A+R L++EM   ++GM  
Sbjct: 336 NSASVRQSGQLIEQLSLGVYDSVRRLLGRLRPRQLDDLTLEQAVRSLMREMELEDRGMVS 395

Query: 410 RLNMGVNPQKLDDTTRVTLYRIVQELLNNICKHAKATRVHISLFPGSE-MVLEVKDDGIG 468
            L   ++   L +  RVTL+R+ QE LNNI KHA A  V +  +   + ++L ++DDG G
Sbjct: 396 HLAWRIDESLLSENQRVTLFRVCQEGLNNIVKHASARAVTLQGWQQEQRLMLVIEDDGCG 455

Query: 469 LPTDWRVRGHGLKGLSERVSALGGQLKMTSSTFQTGTRIIVNLPTK 514
           LP     +G GL G+ ERV+ALGG L ++ +    GTR+ V+LP +
Sbjct: 456 LPPGSGQQGFGLTGMRERVTALGGTLTISCT---HGTRVCVSLPLR 498