Pairwise Alignments

Query, 706 a.a., anaerobic ribonucleoside-triphosphate reductase from Vibrio cholerae E7946 ATCC 55056

Subject, 770 a.a., anaerobic ribonucleoside-triphosphate reductase from Methanococcus maripaludis JJ

 Score =  147 bits (371), Expect = 2e-39
 Identities = 170/719 (23%), Positives = 312/719 (43%), Gaps = 90/719 (12%)

Query: 14  PFNRDRIQAAVESAAEHADQEIAIYALNVALAVELKLRDYDEVHITE--IQTLVENELMQ 71
           PFN+++I   V++  + A  ++   A  +A  VE ++++ +  ++T   I+ +V  +L++
Sbjct: 103 PFNKEKI---VKALIQEAGADLKT-AERIATEVESEVKNLNVTYLTAPMIREIVNTKLIE 158

Query: 72  GPYKALARSYIEYRHDRDVAREKQSKL---TKEIEGLIQESNADLLNENANKDGKVIPTQ 128
                         H  +  R K ++L     +I  LI+  + D  N   N +     + 
Sbjct: 159 --------------HGLEEFRHKHTRLGIPVYDIVKLIERGSKDNANLMHNPE-----SI 199

Query: 129 RDLLAGIVAKHYAKTRILPRDVVQAHESGDIHYHDLDYAPFFPMFNCMLIDLKGMLTHGF 188
              +A    K +A   + P+ +  +H  GDIH HDL+YA    +  C   DL+    +G 
Sbjct: 200 HKWVADETMKQFALLNVFPKYIADSHMRGDIHLHDLEYAAVRTV--CCQHDLRNFFKYGL 257

Query: 189 KMG----NAEIDTP-KSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPYVTASYEKH 243
           K+     +  +  P K    A    A++++     + GG +I+  +  +APY+       
Sbjct: 258 KVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSIDEFNIWIAPYMRGLEYSE 317

Query: 244 LEIAREWDIHSPEAFAKARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGT---- 299
           +    +  I+       AR  +     F S+  E+       G+   +  G  +G     
Sbjct: 318 VRQLMQLFIYEMNQIYAARGGQV---VFSSINLELEVPEYLKGKDA-IKAGQVVGAYEEY 373

Query: 300 SWESRLIQQSILKNRIAGLGKNRKTAVFPKLVFAIKDGLNHKTEDPNYDIKQLALECASK 359
            +E ++I ++++   + G     K  +FP ++F +++   +  +D N D+     E ++K
Sbjct: 374 DYEVKMIAEALVDVLMDGDAYG-KPFLFPNVIFKLRE---NAFKDENKDLLVKIHELSAK 429

Query: 360 RMYPDILNYDKVVEVTGSFKTPMGCRSFLNPYEENGELIHEGR---NNLGVVSLNLPRIA 416
              P  +N     +        MGCR+ L+   E G  I E      N+   ++NLPRIA
Sbjct: 430 WGLPYFINM--FADYQHGNTNAMGCRTRLSG--EWGNSIEESSLRTGNMQWYTINLPRIA 485

Query: 417 LQAKGDINKFYALLDDKLKLARRALDTR--INRLENVKARVAPILYMEGACGVRLKANDS 474
            +A GD  + + +LD+KL +A++AL+ +  I++       V P L  E   G +    DS
Sbjct: 486 YEADGDDGRLFEILDEKLAIAKQALEIKHEISKRRLYHDNVLPFLTQE-FDGEQYYRYDS 544

Query: 475 IADIFKHGRASISLGYIGVHETIMALFGQQKHVYDDVQLREEAVKIIQHLRNAVEQWKKE 534
               F         G++G++E +    G + H  +  +     VK+I H+R   +  KKE
Sbjct: 545 TTKTF---------GFVGLNELLKYHVGSELH--ESPEALAFGVKVISHIRKYADDLKKE 593

Query: 535 TGYAFSLYGTPSENLCSRFCRIDAKQF-----GVVEG-VTDKG--YYTNSFHLDVQKKVN 586
           TG  +++  TP+E+   RF + D K +      VV G + D    YYTNS H+ V   V 
Sbjct: 594 TGLRWTVTQTPAESTAGRFAKFDHKYYPEETKSVVNGNLNDLSSIYYTNSSHVRVNADVT 653

Query: 587 PYDKIDFEMPYPEISSGGFICYGEFPNMQRNVE---ALENVWDYSYHRVPYYGTNTPIDE 643
             +K+  E  + E+ +GG I  G F N +   +    ++     +   + ++     +  
Sbjct: 654 LGEKVGIEEKFHELCNGGHI--GHFWNAEAYADPEVLMDITKKMTKTDIGFWTYTKNLSI 711

Query: 644 CYECGFTGEFDCTSKGFVCPRCGNHEPTKVSVTRRVCGYLGSPDARPFNVGKQEEVKRR 702
           C +C        +     C  CG+    K S   R+ GYL   +   +N  KQ+E+  R
Sbjct: 712 CEKCSLA----MSGLKDNCTGCGSESVEKFS---RITGYL--QNVSNWNKAKQQELLDR 761