Pairwise Alignments

Query, 891 a.a., proton-conducting membrane transporter from Vibrio cholerae E7946 ATCC 55056

Subject, 769 a.a., NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit from Pseudomonas stutzeri RCH2

 Score =  459 bits (1180), Expect = e-133
 Identities = 284/733 (38%), Positives = 422/733 (57%), Gaps = 28/733 (3%)

Query: 39  QTGGNAWQVTWVPGLDLNLSFRLDGLSFLFASLITGIGALIQIYALAYM----KEKAARF 94
           + G     + WVP L ++L+ RLDG + LF  LITGIG L+ IYA AY     KE+AARF
Sbjct: 50  EVGAITETLEWVPALGISLTLRLDGFALLFVLLITGIGTLVTIYAGAYFSHSPKEEAARF 109

Query: 95  SFHLYLTLFMLAMLGVVVSDNILLLFIFWELTTITSYLLIGFNHDKPVSRKNALQSLLVT 154
                + LFM AMLG V+SDN++++F+FWE T++ S++LIGFN  +  +RK ALQSL+VT
Sbjct: 110 L--TLILLFMTAMLGTVLSDNLIVMFVFWEATSLLSFMLIGFNSHRAQARKAALQSLIVT 167

Query: 155 GAGGLALLAGLILLGLMANSYQISVIIEHADHIAQHPWFMPSLILVLLGAFTKSAQFPFH 214
           G GGLAL  G++L+G+   ++ +S + + A  +   P  +P++IL++LGAFTKSAQ PFH
Sbjct: 168 GGGGLALFGGILLIGITLGTFSLSEVAQRAPELLASPLAVPAMILIMLGAFTKSAQLPFH 227

Query: 215 FWLPNAMAAPTPVSAYLHSATMVKAGIYLLARLSPIYASSDFWFYCLTIVGAVTALWCAL 274
           FWLP AM AP P SA+LHSATMVK G+YLLAR   I+     +   L IVG++T L  A+
Sbjct: 228 FWLPQAMEAPAPASAFLHSATMVKLGVYLLARFDLIFEGIPAFGSTLVIVGSLTMLVAAV 287

Query: 275 LAFKQTDLKLMLAYSTNVALGKLTLLLGLGTEVALTAAVLFIFAHSFYKAALFMVVGNID 334
            A      K +LA+ST  +LG L +L+GL  + ++TA + FI AH+ YKAALF   G   
Sbjct: 288 RALSTDGFKEVLAHSTVGSLGVLVMLIGLDGDYSVTALIAFIIAHALYKAALFFCAGTTI 347

Query: 335 KATGTREREKLGNLKSVLLLSLIAAVIAALSKSGVAPMLGFLSKEYMYKSSVESGIAWIS 394
            A G     K+G L   L ++ +AA +AA+S +G+ P LGF++KEY+++S + +   W+ 
Sbjct: 348 HAVGEGRLSKIGGLARRLPMTTLAAGMAAISMAGLPPTLGFITKEYLFESQLNASSGWVV 407

Query: 395 L-VLLLINALMVALAIALLYKPFFGQATKESESHPPKAIEQKKSLWLPAMGLAIASFLLP 453
           + V +L+NA+  A+A     +P++   T+    HP     +   L+L  + L    FL  
Sbjct: 408 VAVAVLVNAVFAAIAGVAAIRPYYLGKTRSEIKHP-----ETLGLYLGPLVLGGLGFLFG 462

Query: 454 VFALDWINQHLVIPAVMAMDPNSVPQAAKLWQGFNIPLALSGITLVLGGVLYLNYATLVT 513
           + A D++ + L+ PA   +  ++V  +  LW GF   LALS   +   G L + Y   + 
Sbjct: 463 L-APDFLVRGLIQPANDVLVGHTVDLSFSLWHGFTPMLALSATVVAFAGGL-IAYWHRIH 520

Query: 514 WLTRLVKPLPK--AEQMFDAVLAYLATLASWQTQMLQQKRSSGYMLLFFAVLALILIYQP 571
           +   L K L +   +  F+A  A L  LA   T+ LQ      Y     A + LI+ Y  
Sbjct: 521 YALSLNKGLARVLGDFGFNAAFAGLLRLAERCTRFLQNGDQHRYTSTVAAAVLLIIGYGV 580

Query: 572 L-----PLPATFSASLFDVHFYEVAIALALIASALLCVLSTSRLLSVLALGMAGFMTTLV 626
           L     PL A  +   FD     + + L +   A     + S L +++A+G+ GF + L+
Sbjct: 581 LASGTRPLIA-MTGGRFDAP--SIIVLLLMCLGAFAATRTPSLLRAMIAVGVVGFGSALI 637

Query: 627 FMIYSAPDVAKTLLLVETLMVVFVVLLMRHVPYLSTVARHSVPRRTLNAVIASVIGASVT 686
           F++  APDVA T   VE L+V+ +V L+  VP  +   R    +R L+ +I++     V 
Sbjct: 638 FLLNGAPDVALTQFSVEVLLVLILVALLLRVPERAASTREPREKR-LDILISAGFALVVF 696

Query: 687 LILLNITAHPIDTTLSDYFAQQSVPGGHGRNIVNVILVDFRAFDTLGEVIVVVMASLVAI 746
           + L    A P+D  +S+++A  S    HGRN+VNV+LVD+RA DTLGEV+VV  A++   
Sbjct: 697 VALAATVALPLDGRISEFYAATSYLEAHGRNVVNVVLVDYRAIDTLGEVVVVAFAAMSVW 756

Query: 747 SL---LPKRTEQP 756
            L   LP+R   P
Sbjct: 757 GLLRALPRRRAAP 769