Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 779 a.a., metal dependent phosphohydrolase from Synechococcus elongatus PCC 7942

 Score =  523 bits (1346), Expect = e-152
 Identities = 284/716 (39%), Positives = 424/716 (59%), Gaps = 41/716 (5%)

Query: 23  LRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLETLQAALLHDVIEDCDVTK 82
           + +++  A   HEGQ R+SGEPYI HPVAVA +L ++      + A  LHDV+ED +VT 
Sbjct: 60  IARAFRFAYSLHEGQYRASGEPYIAHPVAVAGLLRDLGGSAAVICAGFLHDVVEDTEVTP 119

Query: 83  EDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAMVQDIRVILIKLADRTH 142
           E+++  FG+ V +LV+GV+KL K  F  + E QAENFR+M LAM QDIRVIL+KLADR H
Sbjct: 120 EEIEERFGAEVRQLVEGVTKLSKFNFSSKTEQQAENFRRMFLAMAQDIRVILVKLADRLH 179

Query: 143 NMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEELGFEALYPNRYRVLKEVV 202
           NMRTL  L   K++RIA+ET++I+APLA+RLGI  +K ELE+L F+ L   +YR ++  V
Sbjct: 180 NMRTLEHLASTKQKRIAKETMDIFAPLANRLGIGRVKWELEDLSFKYLDAEQYRSIQGHV 239

Query: 203 KAARGNRKEMIQRIHSEIEGRLQEVGL-PARVVGREKNLFSIYNKMKTKEQRFHTIMDIY 261
              R +R+  +++    +  RL ++G+ P  V GR K+L+SIY KM+ +++ FH I D+ 
Sbjct: 240 AEKRADREARLEQSVQILRDRLSQIGIEPVDVSGRPKHLYSIYRKMQMQQKEFHEIFDVA 299

Query: 262 AFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQSLHTSMVGPHGVPVEVQ 321
           A RI+V++ D CYR L  VH  ++P P R KDYI +PK N YQSLHT+++G  G P+E+Q
Sbjct: 300 ALRIIVNSNDECYRALAVVHDAFRPIPGRFKDYIGLPKPNRYQSLHTTVIGLSGRPLEIQ 359

Query: 322 IRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQ----RWMQSLLELQQSAGNSFEFI 377
           IRT +M ++A+ G+AAHW YK   E GG+  +   +     W++ LLE Q    ++ E++
Sbjct: 360 IRTLEMHRIAEYGIAAHWKYK---ESGGSAGKFSTEDEKFTWLRQLLEWQHDLKDAKEYL 416

Query: 378 ENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTCVGARVDRTPYPLSQS 437
           EN+K +LF +++YVFTP G ++ L   +T VDFAY +HT++GN C GA+V+    PL   
Sbjct: 417 ENIKDNLFDEDVYVFTPGGDVIALAQRSTPVDFAYRIHTEVGNRCAGAKVNGRIVPLETR 476

Query: 438 LKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREDSITLGRRLLNHALGE 497
           L +G  VEI++   ARP+  WLN+VVTS A+ +IRQ  K   R+++I  GR +L   LG+
Sbjct: 477 LNNGDIVEILTQKNARPSLDWLNFVVTSAAKNRIRQWYKRSHRDENIARGREMLEKELGK 536

Query: 498 HSVNE-IAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARRL--------------- 541
                 +  E + KV       S DDLLAAIG GE+   ++  R+               
Sbjct: 537 PGFEALLKSEPMQKVAERCNYPSPDDLLAAIGYGEMTITLVVNRIRDAVRSQQPALLEGT 596

Query: 542 ---LGNAD------ELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPG 592
              L +AD      + T+   +    ++ PI G EG++   A CC+P+P + I+A VS G
Sbjct: 597 DTALSDADLAATLSQATQRHDAQRPVSRSPIIGVEGLVYRLAGCCNPLPGESILAVVSRG 656

Query: 593 -RGLVVHRETCPNVRGYQKEPDKYMAVEWTKD-----YDQEFITELKVDMHNRQGALAEL 646
             G+ VHR++CPNV G     D+ + V W  D       Q +   +++ + +R G L ++
Sbjct: 657 NHGIAVHRQSCPNVEGI--AGDRLIPVCWNPDEVKAPRPQTYPVNVQITVLDRVGVLRDI 714

Query: 647 TNVISKTGSNIHGLSTEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRR 702
              +S    N+     +   G+   + + +       L     +IR M   L +RR
Sbjct: 715 LTRLSDNNINVRNAQVKTTPGKPAIIDLCIDLASADQLGRTFSQIRQMSDVLHIRR 770