Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 741 a.a., GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein from Sinorhizobium meliloti 1021

 Score =  455 bits (1171), Expect = e-132
 Identities = 261/733 (35%), Positives = 399/733 (54%), Gaps = 38/733 (5%)

Query: 7   LKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLETL 66
           L +  Q+Y  +     L ++YV A   H  Q R+SG+PYI HP+ VA IL EM LD  T+
Sbjct: 7   LVERVQKYKPDVNEALLNKAYVYAMQKHGQQKRASGDPYISHPLEVAAILTEMHLDESTI 66

Query: 67  QAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAM 126
             ALLHD IED   T++++D  FG  +  LV+G++K+ KL    +K  QAEN RK++LA+
Sbjct: 67  AVALLHDTIEDTTATRQEIDDLFGEDIGALVEGLTKIKKLDLVTKKAKQAENLRKLLLAI 126

Query: 127 VQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEELG 186
             D+RV+L+KLADR HNMRTL  +  +K+ RI+ ET++IYAPLA R+G+ +++ ELE L 
Sbjct: 127 SDDVRVLLVKLADRLHNMRTLDHMSAEKRARISEETMDIYAPLAGRMGMQDMREELENLS 186

Query: 187 FEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGL-PARVVGREKNLFSIYN 245
           F  + P  Y  +   ++      + +I++I  E+   LQ  GL  A+V GR+K  +S++ 
Sbjct: 187 FRHINPEAYETVTRRLQELSERNEGLIKKIEEELSELLQAEGLTDAQVRGRQKKPYSVFR 246

Query: 246 KMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQS 305
           KM++K   F  + D++ FRI+V+   +CYR LG VH+ ++  P R KDY++ PK N YQS
Sbjct: 247 KMQSKSLSFEQLSDVWGFRIIVNDIPSCYRALGIVHTRWRVVPGRFKDYVSTPKQNDYQS 306

Query: 306 LHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGG---TTAQIKAQRWMQS 362
           +HT+++GP    +E+QIRT+ M ++A+ G+AAH  YK      G    T    A  W++ 
Sbjct: 307 IHTTIIGPSRQRIELQIRTKRMHEIAEYGIAAHALYKDRDTVSGDLTRTPTSNAYSWLRR 366

Query: 363 LLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTC 422
            +E      N  EF+E+ K +LF D+++ FTPKG+++ LP GAT +DFAYAVHT+IG+TC
Sbjct: 367 TIESLAEGDNPEEFLEHTKLELFQDQVFCFTPKGQLIALPRGATPIDFAYAVHTNIGDTC 426

Query: 423 VGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRRED 482
           VGA+++    PL   L +G  VEII +    P  AW   VVT +AR  IR+  +   R+ 
Sbjct: 427 VGAKINGRIMPLVTRLNNGDEVEIIRSGIQVPPPAWEEIVVTGKARAAIRRATRAAIRKQ 486

Query: 483 SITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARRLL 542
              LG R+L     E +    + E +  VL  L    ++D +AA+G GEL S+ + R + 
Sbjct: 487 YAGLGYRILERTF-ERAGKTFSREALKPVLHRLGQKDVEDAIAAVGRGELSSLDVLRAVF 545

Query: 543 -------------------------GNADELTEPSK------SGGNKNKLPIRGAEGILL 571
                                    G   +L E SK             LPIRG  G   
Sbjct: 546 PDHQDERVTVKPSADDGWFNMRSAAGMIFKLPERSKEMAAAEQAEGPEALPIRGLSGNAE 605

Query: 572 TFANCCHPIPDDHIIAHVSPGRGLVVHRETCPNVRGYQKEPDKYMAVEWTKD--YDQEFI 629
              +    +P D I+  +   +G+ ++    P ++ + +EP++++ V W  D   +  F+
Sbjct: 606 VHFSPAGAVPGDRIVGIMDKDKGITIYPIQSPILQKFDEEPERWIDVRWDLDEANNSRFM 665

Query: 630 TELKVDMHNRQGALAELTNVISKTGSNIHGLSTEERDGRLYTVTVLLTTKDRVHLAGIMR 689
             + V   N  G LAE+   I+ T  NI  LS          +   L   D   L  +M 
Sbjct: 666 ARIAVSALNEPGTLAEVAQAIATTDVNIRSLSMGRVAADFSELQFDLEVWDLRQLNHLMA 725

Query: 690 KIRTMPHALKVRR 702
           +++ +P    V+R
Sbjct: 726 QLKELPSISMVKR 738