Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 699 a.a., bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) from Shewanella amazonensis SB2B

 Score =  991 bits (2562), Expect = 0.0
 Identities = 483/704 (68%), Positives = 586/704 (83%), Gaps = 5/704 (0%)

Query: 1   MYLFDSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMR 60
           MYLF+ LK+ A  YL   Q+  L+Q+Y VARDAHEGQ R+SGEPYI HPVAVA+IL++MR
Sbjct: 1   MYLFEGLKESASAYLDSGQVALLKQAYQVARDAHEGQMRTSGEPYITHPVAVAKILSDMR 60

Query: 61  LDLETLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFR 120
           LD ETL AALLHD IED  VTKEDL   FG +VA+LV+GVSKLDKLKFRD+KEAQAENFR
Sbjct: 61  LDHETLMAALLHDTIEDTHVTKEDLAELFGDAVADLVEGVSKLDKLKFRDKKEAQAENFR 120

Query: 121 KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKT 180
           KM++AM QDIRVILIKLADRTHNMRTLGALRPDK+RRIARETLEIYAP+A+RLGIHNIKT
Sbjct: 121 KMMMAMTQDIRVILIKLADRTHNMRTLGALRPDKRRRIARETLEIYAPIANRLGIHNIKT 180

Query: 181 ELEELGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNL 240
           ELE+LGF+A YP RYRVLKEVVKAARGNRKE+IQ I + I+ RL++ G+ A+V GREKNL
Sbjct: 181 ELEDLGFQAYYPMRYRVLKEVVKAARGNRKELIQNIKTGIQARLEDAGIHAKVKGREKNL 240

Query: 241 FSIYNKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKA 300
           +SIYNKM+ KE +F  +MDIYAFR++VD+ DTCYRVLG +H LYKPRP R KDYIA+PKA
Sbjct: 241 YSIYNKMRGKELQFQEVMDIYAFRVIVDSIDTCYRVLGAMHGLYKPRPGRFKDYIAIPKA 300

Query: 301 NGYQSLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWM 360
           NGYQSLHTS+ GPHGVPVE+QIRT+DMDQMADKGVAAHW YK  +E G TT Q++A++WM
Sbjct: 301 NGYQSLHTSLFGPHGVPVEIQIRTDDMDQMADKGVAAHWVYKNGNENGSTTTQVRARKWM 360

Query: 361 QSLLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGN 420
           QSLLELQQSA +SFEF+ENVK++LFPDEIYVFTP+GRI+ELP+GATAVDFAY VHTD+GN
Sbjct: 361 QSLLELQQSASSSFEFVENVKTELFPDEIYVFTPEGRILELPVGATAVDFAYEVHTDVGN 420

Query: 421 TCVGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRR 480
           TCVGARV+R  YPLSQ L SGQTVEII+A GA+PNAAWLN+VVT +AR KIRQVLK +++
Sbjct: 421 TCVGARVNRQAYPLSQPLISGQTVEIITAKGAKPNAAWLNFVVTGKARAKIRQVLKNLKQ 480

Query: 481 EDSITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARR 540
           +++I LGRRLLNHALGE+ ++ +APE + KV+ + K   ++ LLA IGLG  MSIVIA+R
Sbjct: 481 DEAIALGRRLLNHALGENKLDSVAPELLDKVIQETKHKDLNSLLADIGLGNAMSIVIAQR 540

Query: 541 LLGNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHRE 600
           L G A     P K     + +PIRGAEG+L++FA CCHPIP D +IAHVSPG+GLVVH E
Sbjct: 541 LTGGA----VPEKQ-SETHLMPIRGAEGMLVSFAKCCHPIPGDAVIAHVSPGKGLVVHME 595

Query: 601 TCPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHGL 660
            C N+RGYQ EPDKY+ V W K    E+   L+V++ N QGALA++T++I+  GSNIH L
Sbjct: 596 NCANIRGYQGEPDKYIPVHWDKVDGVEYQANLRVEIVNHQGALAKITSIIASEGSNIHNL 655

Query: 661 STEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704
           STEERDGR+Y + + ++ +DR+HLA +MR+IR +P  L+  R +
Sbjct: 656 STEERDGRVYLINLRISVRDRIHLANVMRRIRVLPEVLRTSRNR 699