Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 701 a.a., bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) from Shewanella loihica PV-4

 Score =  984 bits (2543), Expect = 0.0
 Identities = 483/705 (68%), Positives = 582/705 (82%), Gaps = 5/705 (0%)

Query: 1   MYLFDSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMR 60
           MYLF+ LK+ A  YL   Q+E L+Q+Y VARDAHEGQ R+SGEPYI HPVAVARILA+MR
Sbjct: 1   MYLFEGLKESASSYLEATQVELLKQAYQVARDAHEGQMRTSGEPYITHPVAVARILADMR 60

Query: 61  LDLETLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFR 120
           LD ETL AALLHD IED  VTKE+L   FG SV ELV+GVSKLDKLKFRD+KEAQAENFR
Sbjct: 61  LDHETLMAALLHDTIEDTPVTKEELSELFGESVGELVEGVSKLDKLKFRDKKEAQAENFR 120

Query: 121 KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKT 180
           KM++AM QDIRVILIKLADRTHNMRTLGALRPDK+RRIARETLEIYAP+A+RLGIHNIKT
Sbjct: 121 KMMMAMTQDIRVILIKLADRTHNMRTLGALRPDKRRRIARETLEIYAPIANRLGIHNIKT 180

Query: 181 ELEELGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNL 240
           ELE+LGF+A YP RYRVLKEVVK+ARGNRKE+IQ I   I+ RL++ GL   V GREKNL
Sbjct: 181 ELEDLGFQAYYPMRYRVLKEVVKSARGNRKELIQNIEGAIKTRLEDTGLKGTVKGREKNL 240

Query: 241 FSIYNKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKA 300
           +SIYNKM  KE +F  +MDIYAFR++VD+ DTCYRV+G +H LYKPRP R KDYIA+PKA
Sbjct: 241 YSIYNKMCNKELQFQEVMDIYAFRVIVDSIDTCYRVMGAMHGLYKPRPGRFKDYIAIPKA 300

Query: 301 NGYQSLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYK-ANSERGGTTAQIKAQRW 359
           NGYQSLHTS+ GPHGVPVE+QIRTEDMDQMADKGVAAHW YK A S + GTT Q++A++W
Sbjct: 301 NGYQSLHTSLFGPHGVPVEIQIRTEDMDQMADKGVAAHWLYKGAGSAQQGTTTQVRARKW 360

Query: 360 MQSLLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIG 419
           MQSLLELQQSA  SFEF+EN K++LFP+EIYVFTP+GRI+ELP+GATAVDFAY VHTD+G
Sbjct: 361 MQSLLELQQSASTSFEFVENFKTELFPEEIYVFTPEGRILELPVGATAVDFAYEVHTDVG 420

Query: 420 NTCVGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMR 479
           NTCVGARV+R  YPLSQ L SGQT+EII+A GARPNAAWLN+VVT +AR KIRQ+LK+++
Sbjct: 421 NTCVGARVNRQAYPLSQPLISGQTIEIITAKGARPNAAWLNFVVTGKARAKIRQLLKSLK 480

Query: 480 REDSITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIAR 539
            +D++ LG+RLLNHALG+  + +I  E I KV+S+ K A++D LLA IGLG  MSIVIA+
Sbjct: 481 EDDAVLLGKRLLNHALGDIKLKDIPQEQIDKVVSETKHATLDSLLADIGLGNAMSIVIAQ 540

Query: 540 RLLGNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHR 599
           RL G+  E  E  +S    N +PIRGAEG+L++FANCC PIP D +IAHVSPG+GLVVH 
Sbjct: 541 RLKGDRVEQHEHKES----NMMPIRGAEGMLVSFANCCRPIPGDAVIAHVSPGKGLVVHM 596

Query: 600 ETCPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHG 659
           E+C N+RGYQ EPDKY+ V W      EF   L++++ N QGALA++T++++  GSNIH 
Sbjct: 597 ESCANIRGYQGEPDKYIPVHWDNAEGVEFQANLRIEIVNHQGALAKITSIVAAEGSNIHN 656

Query: 660 LSTEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704
           LSTEERDGR++ + + ++  DRVHLA +MR+IR +P  L+  R +
Sbjct: 657 LSTEERDGRVFLINLRISVTDRVHLANVMRRIRVLPEVLRTSRNR 701