Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 701 a.a., guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) from Shewanella oneidensis MR-1

 Score =  992 bits (2565), Expect = 0.0
 Identities = 491/705 (69%), Positives = 586/705 (83%), Gaps = 5/705 (0%)

Query: 1   MYLFDSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMR 60
           MYLF+ LK+ A  YL   Q+E L+Q+Y VARDAHEGQ R+SGEPYI HPVAVARILAEMR
Sbjct: 1   MYLFEGLKESASGYLEPEQVELLKQAYQVARDAHEGQMRTSGEPYITHPVAVARILAEMR 60

Query: 61  LDLETLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFR 120
           LD ETL AALLHD IED  VTKEDL   FG SVAELV+GVSKLDKLKFRD+KEAQAENFR
Sbjct: 61  LDHETLMAALLHDTIEDTYVTKEDLAERFGESVAELVEGVSKLDKLKFRDKKEAQAENFR 120

Query: 121 KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKT 180
           KM++AM QDIRVILIKLADRTHNMRTLGALRPDK+RRIARETLEIYAP+A+RLGIHNIKT
Sbjct: 121 KMMMAMTQDIRVILIKLADRTHNMRTLGALRPDKRRRIARETLEIYAPIANRLGIHNIKT 180

Query: 181 ELEELGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNL 240
           ELE+LGF+A YP RYRVLKEVVKAARGNRKE+IQ I + +  RL + G+  +V GREKNL
Sbjct: 181 ELEDLGFQAYYPMRYRVLKEVVKAARGNRKELIQGIEAAVLTRLNDAGIKGKVKGREKNL 240

Query: 241 FSIYNKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKA 300
           +SIYNKM++KE +F  +MDIYAFR++VD+ DTCYRVLG +H LYKPRP R KDYIA+PKA
Sbjct: 241 YSIYNKMQSKELQFQEVMDIYAFRVIVDSIDTCYRVLGAMHGLYKPRPGRFKDYIAIPKA 300

Query: 301 NGYQSLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERG-GTTAQIKAQRW 359
           NGYQSLHTS+ GPHGVPVE+QIRTEDMDQMADKGVAAHW+YK  +E G GTT Q++A++W
Sbjct: 301 NGYQSLHTSLFGPHGVPVEIQIRTEDMDQMADKGVAAHWAYKGGAETGQGTTTQVRARKW 360

Query: 360 MQSLLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIG 419
           MQSLLELQQSA  SFEF+ENVK++LFP+EIYVFTP+GRI+ELP+ ATAVDFAY VHTD+G
Sbjct: 361 MQSLLELQQSASTSFEFVENVKTELFPEEIYVFTPEGRILELPVNATAVDFAYEVHTDVG 420

Query: 420 NTCVGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMR 479
           NTCVGARV+R  YPLSQ L SGQTVEII+A GARPNAAWLN+VVT +AR KIRQVLK+++
Sbjct: 421 NTCVGARVNRQAYPLSQPLISGQTVEIITAKGARPNAAWLNFVVTGKARAKIRQVLKSLK 480

Query: 480 REDSITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIAR 539
            +D+I LGRRLLNHALG+  ++ I  E I KV+ D K AS++ LLA IGLG  MSIVIA+
Sbjct: 481 GDDAIALGRRLLNHALGKTKLDSIPAEQIEKVVRDTKHASLNALLADIGLGNAMSIVIAQ 540

Query: 540 RLLGNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHR 599
           RL+G+  E  E   S    +++PIRGAEG+L+TFANCC PIP D +IAHVS G+GLVVH 
Sbjct: 541 RLIGDNLENQESRDS----HQMPIRGAEGMLVTFANCCRPIPGDAVIAHVSQGKGLVVHM 596

Query: 600 ETCPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHG 659
           E C N+RGYQ EPDKY+ V+W      E+   L+V++ N QGALA++T++I+  GSNIH 
Sbjct: 597 ENCANIRGYQSEPDKYIPVQWDNVEGVEYQANLRVEIVNHQGALAKITSIIAAEGSNIHN 656

Query: 660 LSTEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704
           LSTEERDGR+Y + + ++ KDR+HLA +MR+IR +P  L+  R +
Sbjct: 657 LSTEERDGRVYLINLRISVKDRIHLANVMRRIRVLPEVLRTSRNR 701