Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 714 a.a., (p)ppGpp synthetase I, SpoT/RelA (RefSeq) from Dinoroseobacter shibae DFL-12

 Score =  468 bits (1204), Expect = e-136
 Identities = 262/703 (37%), Positives = 401/703 (57%), Gaps = 18/703 (2%)

Query: 10  VAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLETLQAA 69
           + Q Y        +  +Y   R+ H GQ R SGE Y  HPVAVA ILAE RLD  T+  A
Sbjct: 18  LVQTYNPRTNAALIEAAYDYGREMHRGQLRHSGEEYFTHPVAVAAILAEQRLDDSTIITA 77

Query: 70  LLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAMVQD 129
           LLHD +ED   T  +L++ FG  +AELV+GV+ L  L+   R+  QAENFRK+ +AM +D
Sbjct: 78  LLHDTVEDTRSTFAELESQFGREIAELVNGVTNLTNLQLSSRETKQAENFRKLFMAMSKD 137

Query: 130 IRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEELGFEA 189
           +RVIL+KLADR HNMRT+  +  +K+ + ARET++IYAPLA R+G+  ++ ELE+L F  
Sbjct: 138 LRVILVKLADRLHNMRTIKHMPVEKQVKKARETMDIYAPLAGRMGMQWMRDELEDLSFRV 197

Query: 190 LYPN-RYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNLFSIYNKMK 248
           L P+ R  +++  +K  +    +++Q+I S+I   L   G+ A V GR K  +SI+ KM+
Sbjct: 198 LNPDGRQSIMRRFIKL-QNETGDVVQKITSDIRKELDAHGIEADVYGRAKKPYSIWRKME 256

Query: 249 TKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQSLHT 308
            K+  F  + DIY FR++  + D CY VLG +H  ++  P R KDYI+ PK+NGY+S+HT
Sbjct: 257 AKQLGFSRLSDIYGFRVITHSEDDCYGVLGAIHQRWRAVPGRFKDYISQPKSNGYRSIHT 316

Query: 309 SMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWMQSLLELQQ 368
           ++ G  G  VEVQIRT  M ++A+ GVAAHWSY+   +     A +    W+ SL E  +
Sbjct: 317 TVSGRDGKRVEVQIRTRQMHEVAEAGVAAHWSYRDGVQVENPFA-VDPAEWIASLSERFE 375

Query: 369 SAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTCVGARVD 428
           S+ +  EF+E+VK +++ D+++ FTPKG +V+LP GAT +D+AY +HT IG++CVGA+VD
Sbjct: 376 SSEDHGEFLEHVKLEMYSDQVFCFTPKGEVVKLPKGATPLDYAYGIHTRIGDSCVGAKVD 435

Query: 429 RTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREDSITLGR 488
               PL   LK+GQ+VEII+A G RP A W++ VVT RA+  IR+ L+   R   + LG+
Sbjct: 436 GIRVPLWTRLKNGQSVEIITADGQRPQATWIDIVVTGRAKQAIRRSLREEDRARFVKLGQ 495

Query: 489 RLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARRLLGNADEL 548
            L   A  +H    +  + +      L      +LL+A+G  ++ +  +         E+
Sbjct: 496 ELARVAF-DHVGKRVTDKALKTAAHQLGYGGRLELLSALGSADISARDVV--------EV 546

Query: 549 TEPSKSG-GNKNKLPIRGAEGI----LLTFANCCHPIPDDHIIAHVSPGRGLVVHRETCP 603
             P   G G       R   G+        A CC P+P + I+     G G+ VH   CP
Sbjct: 547 LYPELQGQGGDEVAADRAVVGLHSDQSFERARCCQPVPGERIVGIAYRGHGVRVHAIDCP 606

Query: 604 NVRGYQKEPDKYMAVEW-TKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHGLST 662
            +  ++ E  +++ ++W +  +       L V + N QG L  +  +I +  +NI  L  
Sbjct: 607 ALEEFEDEMRRWIDLQWHSGRHAAVHAVRLDVTIGNDQGVLGRICTLIGEQRANISDLHF 666

Query: 663 EERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRKN 705
            +R    Y + + +  +D  HL  +M  ++       + R ++
Sbjct: 667 VDRKPDFYRLLLEVEVRDLEHLHRVMTAVQADTDVAGLERHRD 709