Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 700 a.a., bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) from Shewanella sp. ANA-3

 Score =  990 bits (2559), Expect = 0.0
 Identities = 487/704 (69%), Positives = 584/704 (82%), Gaps = 4/704 (0%)

Query: 1   MYLFDSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMR 60
           MYLF+ LK+ A  YL   Q+E L+Q+Y VARDAHEGQ R+SGEPYI HPVAVARILAEMR
Sbjct: 1   MYLFEGLKESASGYLEPEQVELLKQAYQVARDAHEGQMRTSGEPYITHPVAVARILAEMR 60

Query: 61  LDLETLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFR 120
           LD ETL AALLHD IED  VTKEDL   FG +VAELV+GVSKLDKLKFRD+KEAQAENFR
Sbjct: 61  LDHETLMAALLHDTIEDTHVTKEDLAEQFGEAVAELVEGVSKLDKLKFRDKKEAQAENFR 120

Query: 121 KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKT 180
           KM++AM QDIRVILIKLADRTHNMRTLGALRPDK+RRIARETLEIYAP+A+RLGIHNIKT
Sbjct: 121 KMMMAMTQDIRVILIKLADRTHNMRTLGALRPDKRRRIARETLEIYAPIANRLGIHNIKT 180

Query: 181 ELEELGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNL 240
           ELE+LGF+A YP RYRVLKEVVKAARGNRKE+IQ I + +  RL + G+  +V GREKNL
Sbjct: 181 ELEDLGFQAYYPMRYRVLKEVVKAARGNRKELIQGIEAAVLTRLNDAGIKGKVKGREKNL 240

Query: 241 FSIYNKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKA 300
           +SIYNKM++KE +F  +MDIYAFR++VD+ DTCYRVLG +H LYKPRP R KDYIA+PKA
Sbjct: 241 YSIYNKMQSKELQFQEVMDIYAFRVIVDSIDTCYRVLGAMHGLYKPRPGRFKDYIAIPKA 300

Query: 301 NGYQSLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWM 360
           NGYQSLHTS+ GPHGVPVE+QIRTEDMDQMADKGVAAHW+YK  ++  GTT Q++A++WM
Sbjct: 301 NGYQSLHTSLFGPHGVPVEIQIRTEDMDQMADKGVAAHWAYKGGADGQGTTTQVRARKWM 360

Query: 361 QSLLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGN 420
           QSLLELQQSA  SFEF+ENVK++LFP+EIYVFTP+GRI+ELP+ ATAVDFAY VHTD+GN
Sbjct: 361 QSLLELQQSASTSFEFVENVKTELFPEEIYVFTPEGRILELPVNATAVDFAYEVHTDVGN 420

Query: 421 TCVGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRR 480
           TCVGARV+R  YPLSQ L SGQTVEII+A GARPNAAWLN+VVT +AR KIRQVLK+++ 
Sbjct: 421 TCVGARVNRQAYPLSQPLISGQTVEIITAKGARPNAAWLNFVVTGKARAKIRQVLKSLKA 480

Query: 481 EDSITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARR 540
           +D+I LGRRLLNHALG+  ++ I  E I KV+ D K A+++ LLA IGLG  MSIVIA+R
Sbjct: 481 DDAIALGRRLLNHALGKTKLDSIPAEQIDKVVRDTKHANLNSLLADIGLGNAMSIVIAQR 540

Query: 541 LLGNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHRE 600
           L+G+  E  E   S    + +PIRGAEG+L+TFANCC PIP D +IAHVS G+GLVVH E
Sbjct: 541 LIGDNLENQESRDS----HLMPIRGAEGMLVTFANCCRPIPGDAVIAHVSQGKGLVVHME 596

Query: 601 TCPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHGL 660
            C N+RGYQ EPDKY+ V+W      E+   L+V++ N QGALA++T++I+  GSNIH L
Sbjct: 597 NCANIRGYQGEPDKYIPVQWDNVEGVEYQANLRVEIVNHQGALAKITSIIAAEGSNIHNL 656

Query: 661 STEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704
           STEERDGR+Y + + ++ KDR+HLA +MR+IR +P  L+  R +
Sbjct: 657 STEERDGRVYLINLRISVKDRIHLANVMRRIRVLPEVLRTSRNR 700