Pairwise Alignments

Query, 295 a.a., methylenetetrahydrofolate reductase from Vibrio cholerae E7946 ATCC 55056

Subject, 295 a.a., 5,10-methylenetetrahydrofolate reductase from Klebsiella michiganensis M5al

 Score =  462 bits (1190), Expect = e-135
 Identities = 226/294 (76%), Positives = 259/294 (88%), Gaps = 1/294 (0%)

Query: 1   MGYTHASHIDALNQNIAELS-DINVSFEFFPPSSPQMEETLWGSVHRLKTLQPKFVSVTY 59
           M + HA+  +ALNQ++AE+   INVSFEFFPP + +ME+TLW S+ RL +L+PKFVSVTY
Sbjct: 1   MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWKSIDRLSSLKPKFVSVTY 60

Query: 60  GANSGERDRTHSIIKAIKDQTGLIAAPHLTCIDATRDELIQIADDYWHNGIQNIVALRGD 119
           GANSGERDRTHSIIK IKD+TGL AAPHLTCIDA+RDEL  IA DYW +GI++IVALRGD
Sbjct: 61  GANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDASRDELRTIAKDYWDSGIRHIVALRGD 120

Query: 120 IPAGGGKPEMYASDLVTLLKSRHDFDISVAAFPEVHPEAKSAQADLLNLKRKVDAGANRA 179
           +P G GKP+MYA DLVTLLK   DFDISVAA+PEVHPEAKSAQADLLNLKRKVDAGANRA
Sbjct: 121 LPPGSGKPDMYAVDLVTLLKEVGDFDISVAAYPEVHPEAKSAQADLLNLKRKVDAGANRA 180

Query: 180 ITQFFFDVESYLRFRDRCVAAGIDVEIVPGILPVSNFKQASRFAAQNNVKVPNWMVKQFE 239
           ITQFFFDVESYLRFRDRCV+AGIDVEI+PGILPVSNFKQA +FA   NV++P WM K FE
Sbjct: 181 ITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPTWMAKMFE 240

Query: 240 GLEDDPVTRQLVGASQAIDMVRVLCREGVKDFHFYTLNRAEMTYALCHTLGVRP 293
           GL++D  TRQLVGA+ A+DMV++L REGVKDFHFYTLNRAEM+YA+CHTLGVRP
Sbjct: 241 GLDNDAETRQLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRP 294