Pairwise Alignments

Query, 803 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Vibrio cholerae E7946 ATCC 55056

Subject, 820 a.a., bifunctional aspartate kinase/homoserine dehydrogenase I from Klebsiella michiganensis M5al

 Score =  348 bits (893), Expect = e-100
 Identities = 254/822 (30%), Positives = 423/822 (51%), Gaps = 50/822 (6%)

Query: 9   KFGGSSLADPECYQRVAKILKSYSKSDDLV-VVSAAGKTTNRLISFVEALSKDGRVAHET 67
           KFGG+S+A+ E + RVA IL+S ++   +  V+SA  K TN L++ +E  +  G+ A   
Sbjct: 5   KFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEK-TIGGQDALTN 63

Query: 68  LHALRQYQSELITKLLSNEAAEPLLSQ---LQQEISVLGELTAPLS------NAQYAWVL 118
           +    +  +EL+  L   +   PL      ++QE + +  +   +S      ++  A ++
Sbjct: 64  IADAERIFAELLQGLADAQPGFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSVNASLI 123

Query: 119 GHGELWSARLLAALLNQQDLPA-VAQDARTFLRAEAGTQPEVDRARSYPLLKA--VLAQH 175
             GE  S  ++A LL  +     V       L      +  VD A S   + A  + A H
Sbjct: 124 CRGEKLSIAIMAGLLEARGHNVTVINPVEKLLAVGHYLESTVDIAESTRRIAASQIPADH 183

Query: 176 TQRRVVITGFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSADPRIV 235
               V++ GF A NE+G+ V+LGRNGSDYSA V+ A        IW+DV GVY+ DPR V
Sbjct: 184 M---VLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV 240

Query: 236 SDACLLPLLRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPES-----GSTRI 290
            DA LL  +   EA EL+   A VLH RT+ P+AQ  +   ++ +  P++     G++R 
Sbjct: 241 PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASRD 300

Query: 291 ERVLASGRGAKIITSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQPDQY 350
           E  L      K I++L+++ +  +S         +   V   + R  +  +       +Y
Sbjct: 301 EDDLP----VKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEY 356

Query: 351 RLRLAYTAEIAPGAFAALQDAAFEAEIKLKEGY----------DLIAAVGAGVTKNPNHC 400
            +           A   ++D   E  ++LKEG            +I+ VG G+       
Sbjct: 357 SISFCVPQSDCARAKRVMED---EFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGIS 413

Query: 401 YGFYQQLNALPVEFISASESSL--SLVAVLRQTPIHSLVNAIHKQLFQAQKHVAIALCGK 458
             F+  L    +  ++ ++ S   S+  V+      + V   H+ LF   + + + + G 
Sbjct: 414 AKFFAALARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGI 473

Query: 459 GNIGSSWLKLFAEQKEKLEQRHGMNFELVAVVDSQTYWFNEQGINPNQVATHFQDEALPN 518
           G +G + ++    Q+  L+ +H ++  +  V +S+    N  G+N      H++DE    
Sbjct: 474 GGVGGALIEQIKRQQSWLKSKH-IDLRVCGVANSRALLTNVHGLN----LEHWRDELAEA 528

Query: 519 QEQSWLKKLGAL-EGYD--EAVVIDVTASEELAEQYLDIAEHGLHLISANKVAGSAAGNY 575
           +E   L +L  L + Y     V++D T+S+ +A+QY D    G H+++ NK A +++ +Y
Sbjct: 529 KEAFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDY 588

Query: 576 YYQVKDAFHKIGRHWLYNATVGAGLPINHTVRDLRESGDDIMALSGIFSGTLSWLFQQYD 635
           Y+Q++ A     R +LY+  VGAGLP+   +++L  +GD+++  SGI SG+LS++F + D
Sbjct: 589 YHQLRHAASSSRRKFLYDTNVGAGLPVIENLQNLLNAGDELLRFSGILSGSLSFIFGKLD 648

Query: 636 GSLPFSELVDLAWQQGLTEPDPRCDLDGSDVMRKLVILARESGLEIEPQNVKVESLVPAE 695
             + FSE   LA + G TEPDPR DL G DV RKL+ILARE+G E+E  ++ VE  +PA 
Sbjct: 649 EGVSFSEATRLAREMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVEPALPAG 708

Query: 696 L-RSVSLDDFLDNSKLLNEQLAERLARAQKQGKVLRYVARLEKNGKASVGVEALEQDHPL 754
              S  +D F+     L+++ A R+A+A+ +GKVLRYV  +E++G   V + A++ + PL
Sbjct: 709 FDASGDVDSFMARLPSLDDEFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPL 768

Query: 755 ANLLPCDNIFAIESKWYRDNPLVIRGPGAGREVTAGAIQSDL 796
             +   +N  A  S +Y+  PLV+RG GAG +VTA  + +DL
Sbjct: 769 FKVKNGENALAFYSHYYQPLPLVLRGYGAGNDVTAAGVFADL 810