Pairwise Alignments

Query, 451 a.a., UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 486 a.a., UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8) from Pseudomonas fluorescens FW300-N2E2

 Score =  163 bits (412), Expect = 1e-44
 Identities = 130/461 (28%), Positives = 213/461 (46%), Gaps = 29/461 (6%)

Query: 3   IHILGICGTFMGGVAMLARQLGHKVTGSDANVYPPMSTMLEAQGIEIIEGFDPVQLEPKP 62
           IH +GI G  M G+A +   LG++V+GSD     P++  LE+ G +I  G    +     
Sbjct: 19  IHFVGIGGVGMCGIAEVLLNLGYQVSGSDLKA-SPVTERLESFGAQIFIGHR-AENAANA 76

Query: 63  DLVVIGNAMSRGNPCVEYVLNHNLRYTSGPQWLQDFLLHDRWVIAVSGTHGKTTTSSMIA 122
           D++V+ +A++  NP V   L   +      + L + L+  R  IAV+GTHGKTTT+S+IA
Sbjct: 77  DVLVVSSAVNTSNPEVATALERRIPVVPRAEMLAE-LMRYRHGIAVAGTHGKTTTTSLIA 135

Query: 123 WVLEHCGYQPGFLVGGVLGNFGISARLGESMFFVVEADEYDSAFFDKRSKFVHYHPRTLV 182
            V    G  P F++GG L   G +A+LG S + + EADE D++       F+H  P   V
Sbjct: 136 SVFAAGGLDPTFVIGGRLNAAGTNAQLGTSRYLIAEADESDAS-------FLHLQPLVAV 188

Query: 183 MNNLEFDHADIFD-NLEAIKRQFHHLVRTVPGNGRILAPKQDEALADVLQRGCWSETEFS 241
           + N++ DH   +D +   +K+ F   +  +P  G  +    D  + ++L         + 
Sbjct: 189 VTNIDADHMATYDGDFNKLKKTFVEFLHNLPFYGLAVVCLDDPVVREILPLIKRPTVTYG 248

Query: 242 -GEQGEWQAEKITADGSQ--FHVLLKGERVGQVNWSLVGDHNVSNALMAIAAARHVGVAP 298
            GE  + +A  +   G Q  F VL        V+ ++ G+HNV NAL  I  A   GV+ 
Sbjct: 249 FGEDVDVRAINVRQQGMQTFFTVLRPDREPLDVSVNMPGNHNVLNALATICIATDEGVSD 308

Query: 299 ELACEALGLFVNTKRRLELKGEI----NGVTVYDDFAHHPTAIELTLGGLRNKVGDKKII 354
           E   + L  F    RR ++ GE+      V + DD+ HHPT +   +  +R    +++++
Sbjct: 309 EAIVQGLSGFQGVGRRFQVYGELPVDGGNVMLVDDYGHHPTEVAAVIKAVRGGWPERRLV 368

Query: 355 AVLEPR--SATMKLGVHKETLAASLHSADSVYLYQPSNIPWSVEEVAKQCQ--------Q 404
            V +P   S T  L      + A  +    + +Y     P    +  + C          
Sbjct: 369 MVYQPHRYSRTRDLYDDFVQVLADANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGQLD 428

Query: 405 PAQVSANMDEFVAMIAKEAQAGDQILVMSNGGFEGIHGKLL 445
           P  +   + E   ++    +AGD +L    G   G+  KLL
Sbjct: 429 PIYIERGV-ELAPLVKPLLRAGDILLCQGAGDIGGLAPKLL 468