Pairwise Alignments

Query, 953 a.a., valine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 948 a.a., Valyl-tRNA synthetase (EC 6.1.1.9) from Pseudomonas fluorescens FW300-N2E2

 Score = 1269 bits (3285), Expect = 0.0
 Identities = 617/955 (64%), Positives = 745/955 (78%), Gaps = 9/955 (0%)

Query: 1   MEKTYNPTSIEQDLYKTWEEQGYFKPHGDTSKDAYSIMIPPPNVTGSLHMGHAFQDTIMD 60
           M+KTY P +IE   Y TWE + YF P G  + D+Y+IMIPPPNVTGSLHMGH F + IMD
Sbjct: 1   MDKTYQPHAIETSWYNTWESENYFAPQG--AGDSYTIMIPPPNVTGSLHMGHGFNNAIMD 58

Query: 61  TLIRCQRMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTKHDYGRDAFIDKIWEWKAE 120
            LIR +RM+G+NTLWQ GTDHAGIATQM+VER++ A+ G+ +HD GR+ F++K+WEWK E
Sbjct: 59  ALIRFRRMQGRNTLWQPGTDHAGIATQMLVERRLEAQ-GQNRHDLGREKFLEKVWEWKDE 117

Query: 121 SGGTITKQLRRLGASVDWDRERFTMDDGFYKAVQEVFVRLYKDDLIYRGKRLVNWDPKLH 180
           SGG I++Q+RRLG+SVDW RERFTMDDG  +AV+E FVRL++D LIYRGKRLVNWD KLH
Sbjct: 118 SGGNISRQIRRLGSSVDWSRERFTMDDGLSEAVKEAFVRLHEDGLIYRGKRLVNWDTKLH 177

Query: 181 TAISDLEVENKETKGHMWHFRYPLADGVKTADGKDYIVVATTRPETMLGDTGVAVNPEDP 240
           TAISDLEVEN + KG +W+ +YPLADG KTA+GKDY++VATTRPETMLGD+ VAVNP D 
Sbjct: 178 TAISDLEVENHDEKGFLWNLKYPLADGAKTAEGKDYLIVATTRPETMLGDSAVAVNPNDE 237

Query: 241 RYKDLIGKEIILPIVGRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHQLPMINI 300
           RY+ LIGK + LP+VGRRIPI+GD++ D E GTGCVKITPAHDFNDYEVGKRH LP++NI
Sbjct: 238 RYQALIGKFVELPLVGRRIPIIGDDYCDPEFGTGCVKITPAHDFNDYEVGKRHNLPLLNI 297

Query: 301 LTFDANIRDAAEVFNSNGEASNAYGTEIPAKYQGMERFAARKAIVAEFEELGLLQEIKDH 360
              +AN+  AA+VFN +G  + +   +IPA+Y G++RF ARK IVA F+  GLL  + DH
Sbjct: 298 FDKNANVLPAAQVFNLDGTLNESIDGQIPAEYAGLDRFEARKQIVAAFDAAGLLVSVDDH 357

Query: 361 DLTVPYGDRGGVVIEPMLTDQWYVRAGILAKPAVEAVENGDIQFVPKQYENMYFSWMRDI 420
            L VP GDR G +IEP LTDQWYV    LA+PA+ AVE+G IQFVPKQYENMYFSWMRDI
Sbjct: 358 ALKVPKGDRSGTIIEPWLTDQWYVSTKPLAEPAIAAVEDGRIQFVPKQYENMYFSWMRDI 417

Query: 421 QDWCISRQLWWGHRIPAWYDEQGNVFVGRNEEEVRAENNIAADVALRQDDDVLDTWFSSA 480
           QDWCISRQLWWGHRIPAWYDE G V+VGR+E EVRA++N+  DVAL QD+DVLDTWFSS 
Sbjct: 418 QDWCISRQLWWGHRIPAWYDESGKVYVGRDEAEVRAKHNLGPDVALAQDNDVLDTWFSSG 477

Query: 481 LWTFGTLGWPEKTPELKVFHPTDVLVTGFDIIFFWVARMIMMTMHFCKDEDGKAQVPFKT 540
           LWTF TLGWP++T  LK FH TDVLVTGFDIIFFWVARMIM+TMH  K+EDG  QVPFKT
Sbjct: 478 LWTFSTLGWPQQTEFLKKFHSTDVLVTGFDIIFFWVARMIMLTMHLVKNEDGTPQVPFKT 537

Query: 541 VYVTGLIRDENGDKMSKSKGNVLDPIDMIDGIDLESLVAKRTGNMMQPQLAAKIEKNTRK 600
           VYV GL+RD  G KMSKSKGNVLDP+D+IDGIDLE+LV KRT  +MQP+LA KIEK TR+
Sbjct: 538 VYVHGLVRDGQGQKMSKSKGNVLDPLDIIDGIDLETLVQKRTSGLMQPKLAKKIEKATRE 597

Query: 601 TFENGIEAYGTDSLRFTLAAMASTGRDINWDMKRLEGYRNFCNKLWNASRYVLMNTEEQD 660
            F  GI +YGTD+LRFT  ++ASTGRDI +DM R+EGYRNFCNK+WNA+RYVL   + +D
Sbjct: 598 EFAEGIASYGTDALRFTFCSLASTGRDIKFDMGRVEGYRNFCNKIWNAARYVL--DKGED 655

Query: 661 CGFAAGAELEYSLADKWIESQFELAAKEFNGHIDNFRLDMAANTLYEFIWNQFCDWYLEL 720
           CG   G   E +LAD+WI SQ +    E    +D FR D+AA  LYEFIWNQ+CDWYLEL
Sbjct: 656 CG-QNGEAFELTLADRWIISQLQRTEAEVTRQLDQFRFDLAAQALYEFIWNQYCDWYLEL 714

Query: 721 TKPVLW--KGTEAQQRATRRTLITVLEKTLRLAHPVIPYITETIWQSVKPLVDGVEGDTI 778
           +KPVLW       +QR TRRTL+ VLE  LRLAHP +P+ITE IWQ + PL  G +G TI
Sbjct: 715 SKPVLWDENAPVERQRGTRRTLVRVLEVALRLAHPFMPFITEEIWQRIAPLA-GAQGKTI 773

Query: 779 MLQALPQYDVANFNQEALDDIEWVKAFITSIRNLRAEYDINPGKPLEVMLKAANEQDAAR 838
           MLQ  P  + +  +  A DDIEW+K F+  +RN+RAE +I PGKPL + LK A+ +D  R
Sbjct: 774 MLQPWPVANESRIDPAAEDDIEWLKTFMLGLRNIRAEMNIGPGKPLTLFLKNASAEDLRR 833

Query: 839 IEANKPVLVSLAKLESIRVLADGEATPACATALVGKSELMIPMAGLIDKDAELDRLAKEI 898
           +  N+ +L  LAKLES+ VLA GE  P  ATALVG+ E+++PMAGLIDK AEL RL KEI
Sbjct: 834 LNENEALLKKLAKLESVTVLAAGEEAPLSATALVGEMEVLVPMAGLIDKAAELARLDKEI 893

Query: 899 AKTQGEIARIEGKLGNEGFVAKAPEAVITKEREKLAGYQEALVKLEQQKATIAAL 953
            + +GE+ R+ GKL N GFV KAP  VI KER KLA  ++AL KL +Q A I++L
Sbjct: 894 LRLKGEVQRVGGKLSNAGFVDKAPAEVIEKERAKLAEAEQALGKLAEQHARISSL 948