Pairwise Alignments

Query, 953 a.a., valine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 886 a.a., valine--tRNA ligase from Methanococcus maripaludis S2

 Score =  308 bits (788), Expect = 1e-87
 Identities = 233/837 (27%), Positives = 380/837 (45%), Gaps = 107/837 (12%)

Query: 10  IEQDLYKTWEEQGYFKPHGDTSKDAYSIMIPPPNVTGSLHMGHAFQDTIMDTLIRCQRMK 69
           +E+ + + WE++  FK   D  +  Y I  PPP  TG +H+GH    T MD + R +RM 
Sbjct: 11  LEKKVQEKWEDEKTFKFLDDEKRPPYIIDTPPPYPTGRMHLGHGLNWTYMDIIARFKRMN 70

Query: 70  GKNTLWQVGTDHAGIATQMVVERKIAAEEGKTKHDYGRDAFIDKIWEWKAESGGTITKQL 129
           G + L+  G D  G+ T++ VE         TK D  R  F     E   E+   +  Q+
Sbjct: 71  GYDVLFPQGWDCHGLPTEVKVEEL----NNITKSDIDRHEFRRLCVELTDENVEKMRGQV 126

Query: 130 RRLGASVDWDRERFTMDDGFYKAVQEVFVRLYKDDLIYRGKRLVNWDPKLHTAISDLEVE 189
           R LG S+DWDRE  TM+  + +  Q  F+++Y+  LIYRGK  VNW P+  TAI+  EVE
Sbjct: 127 RSLGISIDWDREYITMNPDYVRKSQTAFLKMYEKGLIYRGKHPVNWCPRCETAIAFAEVE 186

Query: 190 NKETKGHMWHFRYPLADGVKTADGKDYIVVATTRPETMLGDTGVAVNPEDPRYKDLIGKE 249
            +     + + ++P A+      GK Y+ +AT+RPE M    G+ V+PED RY D++GK 
Sbjct: 187 YQGRTSKLNYIKFPYAEN----SGK-YLEIATSRPELMAACVGIVVHPEDERYSDVVGKT 241

Query: 250 IILPIVGRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHQLPMINILTFDANIRD 309
           + +P+  + + +  D   + E GTG V +    D  D     RH+L             +
Sbjct: 242 VKVPLFDQEVNVYPDSDVEKEFGTGVVMVCTFGDKTDVTWVNRHKL-------------E 288

Query: 310 AAEVFNSNGEASNAYGTEIPAKYQGMERFAARKAIVAEFEELGLLQEIKDHDLTVPYGD- 368
             +  N  G+      TEI  KY G +   ARK I+++      +  IK   L    G  
Sbjct: 289 VKKAINEKGQL-----TEICGKYAGKKSDDARKEIISDLISENYM--IKQEPLEQNVGSC 341

Query: 369 -RGGVVIEPMLTDQWYVRAGILAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQ-DWCIS 426
            R    IE ++ DQW+V    L      A    +I +VP+  +     W+ D+  DWCIS
Sbjct: 342 WRCKTPIEIIVGDQWFVNVTKLLTEVENAAN--EISWVPEHMKARLMKWIEDMGWDWCIS 399

Query: 427 RQLWWGHRIPAWYDEQ-GNVFVGRNEE---EVRAENNIAADVA---LRQDDDVLDTWFSS 479
           RQ  +   IP WY +  G + V + E+   +   E+          L  + DVLDTW  S
Sbjct: 400 RQRLFATPIPVWYCKDCGEIIVAKPEDLPIDPTKESPYTCKCGNSNLVAETDVLDTWMDS 459

Query: 480 ALWTFGTLGWPEKTPELKVFHPTDVLVTGFDIIFFWVARMIMMTMHFCKDEDGKAQVPFK 539
           ++      GW E     K  +P  +   G DII  W    ++ ++    ++      P+ 
Sbjct: 460 SITPLVIAGWLEDEEFFKKHYPVQLRPQGHDIIRTWAFYTMVRSLAITGEK------PWD 513

Query: 540 TVYVTGLIRDENGDKMSKSKGNVLDPIDMIDGIDLESLVAKRTGNMMQPQLAAKIEKNTR 599
            + + G++  E+G KMSKS+GNV++P ++                               
Sbjct: 514 EIVINGMVFGEDGFKMSKSRGNVVEPGEIT------------------------------ 543

Query: 600 KTFENGIEAYGTDSLRFTLAAMASTGRDINWDMKRLEGYRNFCNKLWNASRYVLMNTEEQ 659
                  + YG D+LR   A+ ++ G+D+ +  K +E    F  K+WNA ++  MN  ++
Sbjct: 544 -------KTYGADALRLW-ASNSTIGKDVPFAWKEVEYGGRFLRKIWNACKFAKMNISDE 595

Query: 660 ---DCGFAAGAELEYSLADKWIESQFELAAKEFNGHIDNFRLDMAANTLYEFIWNQFCDW 716
              +        +E +  D WI S+      + +  + N++++     + +F+W++FCD 
Sbjct: 596 TISELKSLNSISIE-NPVDLWILSKLNNLISKVSDDLGNYKINTVVE-IQKFLWHEFCDN 653

Query: 717 YLELTKPVLWKGTEAQQRATRR-----TLITVLEKTLRLAHPVIPYITETIWQSVKPLVD 771
           Y+E+ K  L+   E++     +     TL  V+ ++++L  P  P+  E + +  +  +D
Sbjct: 654 YIEMVKHRLYNKEESESAQQEKLMAQYTLYKVITESVKLLTPFTPHFAEIVGEIYE--ID 711

Query: 772 GVEGDTIMLQALPQYDVANFNQEALDDIEWVKAFITSIRNLRAEYDINPGKPLEVML 828
            +        + P  D    + E     E VK  + SIR     Y  N G PL   L
Sbjct: 712 DLH------TSWPVSDERLISLENEFVGEVVKNTVASIR----RYKSNKGMPLNAEL 758