Pairwise Alignments

Query, 467 a.a., 3-isopropylmalate dehydratase large subunit from Vibrio cholerae E7946 ATCC 55056

Subject, 418 a.a., homoaconitase large subunit from Methanococcus maripaludis S2

 Score =  203 bits (516), Expect = 1e-56
 Identities = 140/462 (30%), Positives = 227/462 (49%), Gaps = 50/462 (10%)

Query: 6   TLYEKIYDAHVVVAAPGETPI-LYIDRHLVHEVTSPQAFDGLREKGRPVRQVSKTFATMD 64
           TL EKI   +V      +  + + +D  + H+ T+P       +    V    K     D
Sbjct: 2   TLAEKIISKNVGKNVYAKDSVEISVDIAMTHDGTTPLTVKAFEQISDKVWDNEKIVIIFD 61

Query: 65  HNVSTTTKDINASGEMARIQMQTLSKNCEEFGVTLYDINHKYQGIVHVMGPELGITLPGM 124
           HN+   T   + +  M  I  + + K     G+  Y ++   +GI H + PE G   P M
Sbjct: 62  HNIPANT---SKAANMQVITREFIKKQ----GIKNYYLDG--EGICHQVLPEKGHVKPNM 112

Query: 125 TIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEVRGKVAPGITAKD 184
            I   DSHT THGAFG+ A G G +++ +V AT        +T+++ V G+    I+ KD
Sbjct: 113 IIAGADSHTCTHGAFGAFATGFGATDMGYVYATGKTWLRVPETIRVNVTGE-NENISGKD 171

Query: 185 IVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIELGAKAGLIAPDATTFNY 244
           I+L    +    G T   +E+ G A+ +LSM+ RM + NMAIE+G KAG+I  D TT+ Y
Sbjct: 172 IILKTCKEVGRRGATYMSLEYGGNAVHNLSMDERMVLSNMAIEMGGKAGIIEADDTTYRY 231

Query: 245 IKGRKFAPQGSDWDAAVDYWQTLKTDEDAQFDAVVTLE--ASEIKPQVTWGTNPGQVIAV 302
           ++       G   +  ++  +   T ++++ D   T+E   + ++ QV    +P  V  V
Sbjct: 232 LEN-----AGVSREEILELKKNKITVDESEEDYYKTIEFDITGMEEQVACPHHPDNVKGV 286

Query: 303 DEPIPSPSQFADPVERSSAEKALAYMGLEAGKMLSDYKVDKVFVGSCTNSRIEDMRAAAA 362
            E                               +   ++++VF+GSCTN R+ D+R AA 
Sbjct: 287 SE-------------------------------VEGTELNQVFIGSCTNGRLNDLRIAAK 315

Query: 363 VAKGKKVASHVQALIVPGSEQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLGP 422
             KGKKV  + + +++P S+ +  +A  EGL  IF+++G     PGC  CL  +   LG 
Sbjct: 316 YLKGKKVNENTRLIVIPASKSIFKEALNEGLIDIFVDSGALICTPGCGPCLGAHQGVLGD 375

Query: 423 GERCASTSNRNFEGRQGR-DGRTHLVSPAMAAAAAIAGHFVD 463
           GE C +T+NRNF+GR G  + + +L SP +AA +A+ G+  +
Sbjct: 376 GEVCLATTNRNFKGRMGNTNAQVYLSSPKIAAKSAVKGYITN 417