Pairwise Alignments

Query, 516 a.a., 2-isopropylmalate synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 386 a.a., homocitrate synthase family protein from Methanococcus maripaludis S2

 Score =  230 bits (586), Expect = 8e-65
 Identities = 140/352 (39%), Positives = 203/352 (57%), Gaps = 14/352 (3%)

Query: 7   IFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDIIEAGFPVSSPGDFESVQTIAKNIK 66
           ++DTTLRDGEQ         +KL+IA  L+ L +  IEAGFP+ S  + +++++I     
Sbjct: 20  LYDTTLRDGEQTPGVCFAGDQKLEIAKKLDELKIKQIEAGFPIVSENERKAIKSITGEGL 79

Query: 67  NSRVCALSRAVAKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVAMAVKAV 126
           N+++ ALSR + +DID A E     +   I TFI+TS +H++ KL ++ D+V  M +KAV
Sbjct: 80  NAQILALSRVLKEDIDKAIEC----DVDGIITFIATSPMHLKYKLHKNLDEVEEMGMKAV 135

Query: 127 KHARQYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEFGGIIQT 186
           ++A+ +   V FS EDA RTP++++ R+ + A   GA  ++I DT+G   P     I   
Sbjct: 136 EYAKDHGLFVAFSAEDATRTPLEDIIRIHKNAEEHGADRVHIADTLGCATPQAMYHICSE 195

Query: 187 LFNRVPNIDKAIISVHCHDDLGMSVANSIAAIQAGARQVEGTINGIGERAGNCALEEIAM 246
           L     ++ KA I VHCH+D G +V NSI  +  GA+ V  T+NGIGERAGN A+EEIAM
Sbjct: 196 LSK---HLKKAHIGVHCHNDFGFAVINSIYGLIGGAKAVSTTVNGIGERAGNAAIEEIAM 252

Query: 247 IIKTRQELLGVTTGIKHDEISRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIHQDGMLK 306
            +K    L     G+  + ++  SKLV     + I  NK +VG   F H SGIH D +L+
Sbjct: 253 ALKV---LYDHDMGLNTEILTEISKLVENYSKIKIPENKPLVGEMVFYHESGIHVDAVLE 309

Query: 307 NKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYNENEYNLDALYE 358
           N  TYE   PE IG K + + L   SG  AV   +  +G    E + D L+E
Sbjct: 310 NPLTYEPFLPEKIGQKRKII-LGKHSGCRAVAHRLQELGL---EASRDELWE 357