Pairwise Alignments

Query, 516 a.a., 2-isopropylmalate synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 522 a.a., 2-isopropylmalate synthase (NCBI ptt file) from Shewanella oneidensis MR-1

 Score =  724 bits (1870), Expect = 0.0
 Identities = 371/511 (72%), Positives = 425/511 (83%), Gaps = 2/511 (0%)

Query: 1   MNNQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDIIEAGFPVSSPGDFESVQT 60
           M+N+VIIFDTTLRDGEQAL+ASL+VKEKLQIA ALERLGVD++E GFPVSSPGDFESVQT
Sbjct: 1   MSNRVIIFDTTLRDGEQALAASLSVKEKLQIAMALERLGVDVMEVGFPVSSPGDFESVQT 60

Query: 61  IAKNIKNSRVCALSRAVAKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVA 120
           IA+ IKNSRVCALSRA+ KDIDAAA+AL VAE FRIHTFISTSTIHV+ KL+RS++ V+ 
Sbjct: 61  IARTIKNSRVCALSRALEKDIDAAAQALSVAEQFRIHTFISTSTIHVESKLKRSFEQVLE 120

Query: 121 MAVKAVKHARQYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEF 180
           MAV AVK+AR++TDDVEFSCEDAGRTPIDNLCRMVEAAI+AGARTINIPDTVGYTVPSEF
Sbjct: 121 MAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEAAIHAGARTINIPDTVGYTVPSEF 180

Query: 181 GGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAIQAGARQVEGTINGIGERAGNCA 240
           G IIQTLFNRVPNID+AIISVHCHDDLG+SVANSI A+Q GARQ+E T+NGIGERAGNC+
Sbjct: 181 GSIIQTLFNRVPNIDQAIISVHCHDDLGLSVANSITAVQHGARQIECTMNGIGERAGNCS 240

Query: 241 LEEIAMIIKTRQELLGVTTGIKHDEISRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIH 300
           LEEIAMI+ TR+ LLG  TGI   EI RTS LVSQLCNMPIQSNKAIVGANAF+HSSGIH
Sbjct: 241 LEEIAMILATRKNLLGFETGINAKEIHRTSNLVSQLCNMPIQSNKAIVGANAFTHSSGIH 300

Query: 301 QDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYNENEYNLDALYEDF 360
           QDGMLK +NTYEIMTPESIGL    LN+TSRSGR  +K  M+ MGY+  +YNLDALYE F
Sbjct: 301 QDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMEEMGYSSQDYNLDALYEQF 360

Query: 361 LKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSV--MATTSIKLLCGGEEK 418
           L LAD+KGQVFDYDLEAL        ED+FY+L  L VQS S   +AT ++++  GGE K
Sbjct: 361 LHLADKKGQVFDYDLEALAFIEAQAAEDNFYQLRQLVVQSDSTEGVATATVRIEVGGEIK 420

Query: 419 CEAAVGNGPVDALYQCIYRITGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTG 478
            EAA GNGPVDA Y  I R T   I +  + L AKG G+D LGQ DI A Y  + +HG G
Sbjct: 421 TEAATGNGPVDAAYNAIARATDRRIDIISYKLGAKGVGQDALGQVDITAVYHEQNFHGVG 480

Query: 479 VSTDIVEASGQALLHVINSIHRADQIAQIKQ 509
           ++TD+VEAS +AL+HV+N   RAD++A  KQ
Sbjct: 481 LATDVVEASARALVHVMNLTCRADKVADYKQ 511