Pairwise Alignments

Query, 409 a.a., phosphoglycerate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 523 a.a., phosphoglycerate dehydrogenase from Methanococcus maripaludis S2

 Score =  211 bits (537), Expect = 4e-59
 Identities = 144/399 (36%), Positives = 211/399 (52%), Gaps = 25/399 (6%)

Query: 12  KILLLEGLHPSSVEVLQAAGYSNIEYHKGSLEEAELIKAIKDVHFVGIRSRSNLTEKVIN 71
           KIL+ + LH S+VE+L+ AG   +E   G   E EL   IKDV  + IRS +  T ++I 
Sbjct: 3   KILITDPLHESAVEILKQAG--EVEVATGLTVE-ELKLKIKDVDALVIRSGTTATREIIE 59

Query: 72  AAEKLVAIGCFCIGTNQVDLNAAAKRGIPVFNAPFSNTRSVAELVLGEILLLLRGIPEKN 131
           A+E L  I    +G + VDL+AA ++GI V NAP +++ SVAEL+ G +L   R IP+  
Sbjct: 60  ASENLKVIARAGVGVDNVDLDAATEKGIVVVNAPDASSISVAELLFGMMLAAARNIPQAT 119

Query: 132 ALAHRGIWKKSADNSYEARGKRLGIIGYGHIGTQLGIIAENLGMHVYFYD--IESKLSLG 189
           A    G W + +    E  GK LGI+G G IG Q+   A+  GM +  YD  I   ++  
Sbjct: 120 ASIKSGKWDRKSFKGMEIYGKTLGIVGLGRIGQQVAKRAQAFGMTIVAYDPYIPEDVASE 179

Query: 190 NATQVHTLSELLNKCDVISLHVPETAGTKNMMGAEEFARMKPGAIFINAARGTVVDIPAL 249
              ++ T+ EL    D I+LHVP T  TK+M+G E+ A MK   + +N ARG ++D  AL
Sbjct: 180 LGIKLLTVDELCTVSDFITLHVPLTPKTKHMIGKEQIALMKSNMVIMNCARGGLIDEAAL 239

Query: 250 CNALESGHIAGAAIDVFPEEPASNKEPFESPLMKFDNVILTPHVGGSTQEAQENIGIEVA 309
            +AL SG I  AA+DVF +EP     P ESPL+  +N+I TPH G ST+EAQ + G  VA
Sbjct: 240 YDALNSGKIKAAALDVFEQEP-----PKESPLLTLNNLIGTPHQGASTEEAQLSAGTIVA 294

Query: 310 GKLAKYSDNGSTLSSVNFPEVSLPEHRSCSRLLHIHANRPGILTQINTIFAEEGINIAAQ 369
            +  K     S  + VN P V   + +     +               + AE+  ++A Q
Sbjct: 295 EQTVKILKGESAENVVNLPMVPTEKMKKLKPYM---------------VLAEKMGSMAIQ 339

Query: 370 YLQTTAEIGYVVIDVETARSEEALTKLKAIDGTIRARIL 408
           YL  + E+  +      A+ +  + K   + G +   +L
Sbjct: 340 YLDNSIELLEITYMGGLAKEKTEILKRSFLKGILAPILL 378



 Score = 34.7 bits (78), Expect = 7e-06
 Identities = 16/67 (23%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 345 HANRPGILTQINTIFAEEGINIAAQYLQTTAEIGYVV--IDVETARSEEALTKLKAIDGT 402
           H +RPG++ ++  +  E GINIA   +      G+ +  +D++   S+E L +++ ++  
Sbjct: 456 HIDRPGMVGKVGVLLGEHGINIAGMQVGRREPGGHSIMFLDIDHMISDEVLDEIRKMENV 515

Query: 403 IRARILH 409
             A+ ++
Sbjct: 516 RAAKSIN 522