Pairwise Alignments

Query, 738 a.a., GTP diphosphokinase from Vibrio cholerae E7946 ATCC 55056

Subject, 701 a.a., GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) from Pseudomonas fluorescens FW300-N2E2

 Score =  395 bits (1014), Expect = e-114
 Identities = 229/681 (33%), Positives = 370/681 (54%), Gaps = 43/681 (6%)

Query: 64  ILITLSMDRPTLVAALLFPIATSGVLDNESLEEGYGREVVKLIHGVEEMAAIGQLNVTMH 123
           IL  + MD  +L+AA+L  +     +  E+L+  +G  V +L+ GV ++    Q+N    
Sbjct: 55  ILADMHMDHQSLMAAMLHDVIEDTGIAKEALQAQFGETVAELVDGVSKLT---QMNFE-- 109

Query: 124 GSEASAQVDNVRRMLLAMVDDFRCVVIKLAERICNLREVKNEPDEVRRVAAKECANIYAP 183
            ++A AQ +N ++M +AM  D R +++KLA+R+ N+R ++    E RR  AKE   IYAP
Sbjct: 110 -TKAEAQAENFQKMAMAMARDIRVILVKLADRLHNMRTLEVLSGEKRRRIAKETLEIYAP 168

Query: 184 LANRLGIGQLKWEIEDYAFRYQQPDTYKQIAKQLSERRIVREQYIRDFVSDLRAEMKQSG 243
           +ANRLG+  ++ E ED  F+   P    +I + +   R  R++ +      L   +   G
Sbjct: 169 IANRLGMHAIRIEFEDLGFKAMHPMRSARINQAVKRARGNRKEIVNKIEESLSHCLAIDG 228

Query: 244 INAEVSGRPKHIYSIWRKMQKKSLAFDELFDVRAVRIIADKLQDCYAALGIVHTKYKHLP 303
           I  EVSGR KH+Y I++KM+ K  AF+E+ DV A RII DK+  CY  LG VH  YK LP
Sbjct: 229 IEGEVSGRQKHLYGIYKKMRGKRRAFNEIMDVYAFRIIVDKVDTCYRVLGAVHNLYKPLP 288

Query: 304 NEFDDYVANPKPNGYQSIHTVILGPEGKTIEIQIRTKQMHEESELGVAAHWKYK-EGSSA 362
             F DY+A PK NGYQS+HT + G  G  IEIQIRT++M E +  G+AAHW YK  G   
Sbjct: 289 GRFKDYIAIPKANGYQSLHTTLFGMHGVPIEIQIRTREMEEMANNGIAAHWLYKSSGDEQ 348

Query: 363 ARSGYDEKITWLRKLLDWQEEMSDSGEMLDELRSQVFDDRVYAFTPKGDVVDLPMGATPL 422
            +S +     W++ +L+ Q+   +S E ++ ++  +F D VY FTPKG +++LP G+T +
Sbjct: 349 PKSTHARARQWVKGVLEMQQRAGNSLEFIESVKIDLFPDEVYVFTPKGRIMELPKGSTAV 408

Query: 423 DFAYHIHSEVGHRCIGAKVAGRIVPFTHKLQMGDQVEIITAKEPNPSRDWLNPSLGFVHS 482
           DFAY +H++VG+ CI  ++  R+ P +  LQ G  VEI++A    P+  WLN    FV +
Sbjct: 409 DFAYAVHTDVGNSCIACRINRRLAPLSEPLQSGSTVEIVSAPGARPNPAWLN----FVVT 464

Query: 483 GRARAKINAWFRKQSREKNLEAGREILEIELAKIGANLKHAEA----YALKRFNVNSVDE 538
           G+AR  I    + Q R +++  G  +L   L    ++L    A      L  + +  +++
Sbjct: 465 GKARTHIRHALKLQRRSESISLGERLLNKVLNGFDSSLDKIPAERVQLMLNEYRLELIED 524

Query: 539 MYVGIGSGDLRINQIVNHINALVNKPTAEEEDKLALEKLQENKTLTPNRPHKDAVVVEGV 598
           +   IG G        N +  +V +    E ++L           +P  P    + + G 
Sbjct: 525 LLEDIGLG--------NRMAYVVARRLLGEGEQLP----------SPEGP----LAIRGT 562

Query: 599 DNLMTHLARCCQPIPGDEIRGYITQGRGISVHRSDCEQLEELSLHAPERIIDTVWGSGFV 658
           + L+   A+CC PIPGD I G+++ G+G+ VH  +C  + E+  H PE+ I   W     
Sbjct: 563 EGLVLSYAKCCTPIPGDPIVGHLSAGKGMVVHLDNCRNISEIR-HNPEKCIQLSWAKDVT 621

Query: 659 GSYLLTVRVEAMERSGLLKDITTLL--ANEKVKVASMKSRSDYKRQIIIMDFDLEVNNVE 716
           G + + +RVE   + GL+  + + +  A+  ++  SM  R     +I ++   + V++  
Sbjct: 622 GEFNVELRVELEHQRGLIALLASSVNAADGNIEKISMDERDG---RISVVQLVVSVHDRV 678

Query: 717 ALARVSKRIEQIKDVMLVKRL 737
            LARV K++  +  V+ + R+
Sbjct: 679 HLARVIKKLRALTGVIRITRM 699