Pairwise Alignments
Query, 948 a.a., [glutamate--ammonia-ligase] adenylyltransferase from Vibrio cholerae E7946 ATCC 55056
Subject, 958 a.a., glutamate-ammonia-ligase adenylyltransferase from Caulobacter crescentus NA1000
Score = 305 bits (782), Expect = 7e-87
Identities = 256/873 (29%), Positives = 392/873 (44%), Gaps = 51/873 (5%)
Query: 11 AELHYQSLISEHPHIANWPSSVLNQLRYVLGLSQFVAQTLQRDDPLCQVLPSLLA-KPSR 69
AE Y+++ + L V S ++A +RD + LP +L P
Sbjct: 20 AERAYEAIAKRAGEAMGQVDAAWGSLAPVFAASPYLAGLARRDG---KRLPRILGGDPGE 76
Query: 70 EQYYRSELAQWLAECQDEAVAQKRLRQFRNQEMVYIAWRDFCASWTLEESLSHLSQLAEA 129
A+ +A D A++ LR+ + + A D W L++ L++ A+A
Sbjct: 77 TLAAILAAAEAVAAEPDFETARRVLRELKADLHLLTAISDLGGVWDLDQVTGALTRFADA 136
Query: 130 LIFESY-----QWLYQRCCLEMGTPCNAQGEAQPMLIIGMGKLGGGELNFSSDIDL-IFT 183
++ + Q + + +G + G A + + MGK G ELN+SSDID IF
Sbjct: 137 VLHAALAQAVRQEVSRGALTHVGD--GSAGPAPGLFCVAMGKHGAFELNYSSDIDFSIFY 194
Query: 184 YPENGETQGARRSIANAQFFTRLGQRLIKLLDQSTPDGFCYRVDMRLRPFGDSGPLAMSY 243
PE A A R+ L ++L + T DG+ +R+D+RLRP S P AM
Sbjct: 195 APEKLPVAEGHEPQAVA---VRIANHLGRILQERTGDGYVFRIDLRLRPDPSSTPPAMPV 251
Query: 244 AALEDYYQEQGRDWERYAMIKARVMGREMYPQYQELRQMLRPFVFRRYIDFSAIQSLRRM 303
A DYY+ G++WER A IKAR+ + + + L+PF++RR +DF+AI + +
Sbjct: 252 DAAMDYYESVGQNWERAAHIKARIAAGDA-AEGAAFLEGLQPFIWRRNLDFAAIADIHSI 310
Query: 304 KSMISS---EVRRRGLSNNIKLGAGGIREVEFIAQVFQLIRGGREPSLRKRGLLETLDAI 360
K I + + R ++KLG GGIRE+EF Q QLI GGR+P LR L+ L A+
Sbjct: 311 KRQIHTYKVDDRLTAKGADLKLGRGGIREIEFFVQTQQLILGGRQPDLRSPRTLDALQAL 370
Query: 361 AELELLTREQVQDLRDAYRFLRRLENLLQAMADKQTQTLPDKEDDQLRLSIAIGLADWPS 420
A +T E L AY+ LR LE+ Q +AD QT LP+ + ++ +++ G +
Sbjct: 371 AAAGHVTPEDAAWLTQAYKDLRALEHRAQMIADDQTHKLPESDVERKKVAALWGEGNLRV 430
Query: 421 LQREVSEHMQRVHRVFATLIGEEDEEEEHTVARHFHELWDMAHKPEVIEHIIEQDLGLSD 480
V + ++ V+ + L E+ + F + D PE + + + +G S
Sbjct: 431 FDAAVGKMLKGVNLRYGRLFAGEEALSSRFGSLVFTGVED---DPETLATL--KRMGFSS 485
Query: 481 AGEQIRTITQFKDDLAKRTIGPRGREVLNRLMPKVYQAVFAHPDAEFGLSRVLALLHSIA 540
TI + T RGRE+ RL P++ A A + +R ++
Sbjct: 486 PERVAATIRGWHHGHIAATRTERGRELFTRLAPRLLDAANATGAPDQAFNRFSDFFSRLS 545
Query: 541 TRTTYLELLDEHPAALVQLVRLCTASPMISEQLARYPILLDELIDPQHLYNPIPLESYQT 600
+ L P +V + +P ++ +A+ P LD L+DP + PI +
Sbjct: 546 SGVQIQSLFLAQPRLFELIVEVMAFAPRLAATMAKRPTALDALLDPT-FFGPIETPA--- 601
Query: 601 ELRDFLARIPEEDMEQQMEGLRQFKQISILRIAAADIAGVLPVMKVSDHLTYLAEAIVEA 660
+A ED E M+ R+ + RI ++G + LA+ I+
Sbjct: 602 -----IAPWDPEDFEGAMDAARRLFRDQSFRIGVRVMSGTADARDIGRAFAELADLIIGG 656
Query: 661 VVSQAWLQVSSKYGEPTHLKHRDGRGF----AVVGYGKVGGWELGYNSDLDIVFMHDCPV 716
+ A +V R G F AVV GK G E+ SDLD++ ++
Sbjct: 657 LAPAALAEVE-----------RIGGAFPGQVAVVALGKAGSREMTAKSDLDLMTLYVADD 705
Query: 717 EVNTDGEKSIDGRQFYLRLAQRIIHIFSTRTASGILYEVDTRLRPSGASGLLVSPTDAFD 776
+ K FY RL QR+ S T G LYEVD +LRPSG G + AF+
Sbjct: 706 PRSMSALKDWSAEVFYARLTQRLTSALSAPTGEGTLYEVDLKLRPSGTKGPVAVSFAAFE 765
Query: 777 EYQRQEAWTWEHQALVRARMIYGDAPLQQAFA-NTRHQILCLPREEHKLKQEVVEMRIKM 835
Y +EA TWE AL RAR+++ +P +A A L PR K +V+EMR M
Sbjct: 766 HYYEREAETWELLALTRARVVWASSPDFKARAEGAIAAALRRPRAWKKTAADVIEMRQLM 825
Query: 836 RDHLGGKKAGRFMLKQDEGGITDIEFLAQYLVL 868
GK G + LK D GG+ DIEF AQ+L L
Sbjct: 826 ERERPGK--GDWDLKLDPGGLVDIEFAAQFLQL 856
Score = 110 bits (276), Expect = 3e-28
Identities = 100/345 (28%), Positives = 152/345 (44%), Gaps = 24/345 (6%)
Query: 611 EEDMEQQMEGLRQFKQISILRIAAADIAGVLPVMKVSDHLTYLAEAIVEAVVSQAWLQVS 670
E D E LR+ K L A +D+ GV + +V+ LT A+A++ A ++QA Q
Sbjct: 91 EPDFETARRVLRELKADLHLLTAISDLGGVWDLDQVTGALTRFADAVLHAALAQAVRQEV 150
Query: 671 SKYGEPTHLKHRDGR-----GFAVVGYGKVGGWELGYNSDLDIVFMHDCPVEVNTDGEKS 725
S+ G TH+ DG G V GK G +EL Y+SD+D + +G +
Sbjct: 151 SR-GALTHVG--DGSAGPAPGLFCVAMGKHGAFELNYSSDIDFSIFYAPEKLPVAEGHEP 207
Query: 726 IDGRQFYLRLAQRIIHIFSTRTASGILYEVDTRLRPSGASGLLVSPTDAFDEYQRQEAWT 785
+ +R+A + I RT G ++ +D RLRP +S P DA +Y
Sbjct: 208 ---QAVAVRIANHLGRILQERTGDGYVFRIDLRLRPDPSSTPPAMPVDAAMDYYESVGQN 264
Query: 786 WEHQALVRARMIYGDAPLQQAFAN-------TRHQILCLPREEHKLKQEVVEMRIKMRDH 838
WE A ++AR+ GDA AF R+ + H +K+++ K+ D
Sbjct: 265 WERAAHIKARIAAGDAAEGAAFLEGLQPFIWRRNLDFAAIADIHSIKRQI--HTYKVDDR 322
Query: 839 LGGKKAGRFMLKQDEGGITDIEFLAQYLVLRFSHQQPKLTRWSDNVRIFESLMNHQVMSE 898
L K A LK GGI +IEF Q L +QP L R + ++L ++
Sbjct: 323 LTAKGAD---LKLGRGGIREIEFFVQTQQLILGGRQPDL-RSPRTLDALQALAAAGHVTP 378
Query: 899 SQALALTHAYTSMRDQIHRRNLLNQSADVRDSQFVVEREQVIQAW 943
A LT AY +R HR ++ + + VER++V W
Sbjct: 379 EDAAWLTQAYKDLRALEHRAQMIADDQTHKLPESDVERKKVAALW 423
Score = 103 bits (258), Expect = 4e-26
Identities = 74/282 (26%), Positives = 135/282 (47%), Gaps = 5/282 (1%)
Query: 161 IIGMGKLGGGELNFSSDIDLIFTY-PENGETQGARRSIANAQFFTRLGQRLIKLLDQSTP 219
++ +GK G E+ SD+DL+ Y ++ + A + + F+ RL QRL L T
Sbjct: 678 VVALGKAGSREMTAKSDLDLMTLYVADDPRSMSALKDWSAEVFYARLTQRLTSALSAPTG 737
Query: 220 DGFCYRVDMRLRPFGDSGPLAMSYAALEDYYQEQGRDWERYAMIKARVMGREMYPQYQEL 279
+G Y VD++LRP G GP+A+S+AA E YY+ + WE A+ +ARV+ P ++
Sbjct: 738 EGTLYEVDLKLRPSGTKGPVAVSFAAFEHYYEREAETWELLALTRARVVWASS-PDFKAR 796
Query: 280 RQMLRPFVFRRYIDFSAIQS-LRRMKSMISSEVRRRGLSNNIKLGAGGIREVEFIAQVFQ 338
+ RR + + + M+ ++ E +G ++KL GG+ ++EF AQ Q
Sbjct: 797 AEGAIAAALRRPRAWKKTAADVIEMRQLMERERPGKG-DWDLKLDPGGLVDIEFAAQFLQ 855
Query: 339 LIRGGREPSLRKRGLLETLDAIAELELLTREQVQDLRDAYRFLRRLENLLQAMADKQTQT 398
L + LR + E L A+ E L + L A+R + L L++ +
Sbjct: 856 LAHAAADGPLR-QNTGEALAALREAGLADAGALSRLEAAWRLEQDLSQLIKVALEDGADV 914
Query: 399 LPDKEDDQLRLSIAIGLADWPSLQREVSEHMQRVHRVFATLI 440
+ + + L+ A G+ + SL+ ++++ + ++
Sbjct: 915 EVEPKAFKALLAKAGGVTQFKSLKPKLAKAKAEARAAYEAVV 956