Pairwise Alignments

Query, 886 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Vibrio cholerae E7946 ATCC 55056

Subject, 881 a.a., pyruvate dehydrogenase E1 component, homodimeric type from Pseudomonas stutzeri RCH2

 Score = 1058 bits (2737), Expect = 0.0
 Identities = 529/882 (59%), Positives = 664/882 (75%), Gaps = 9/882 (1%)

Query: 7   DVDALETQEWLAALESVVREEGVERAQYLLEQVLEKARLDGVDMPTGVTTNYINTIPAAQ 66
           D+D +ETQEWL ALESV+  EG +RA YL+ ++ E A   G  +P G+TT Y NTIP  +
Sbjct: 3   DLDPVETQEWLDALESVLDREGEDRAHYLMTRMGELATRSGTPLPYGITTPYRNTIPVTR 62

Query: 67  EPAYPGDTTIERRIRSIIRWNAIMIVLRASKKDLELGGHMASFQSSAAFYETCFNHFFRA 126
           E   PGD  +ERRIRS++RWNA+ +V+RA+ KD +LGGH+++F SSA  Y+  FN+FF+A
Sbjct: 63  EAKMPGDLFMERRIRSLVRWNALAMVMRANLKDPDLGGHISTFASSATLYDIGFNYFFQA 122

Query: 127 PNEKDGGDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPKLMPEFW 186
           P E+ GGDL+YYQGH SPGIYARAF+EGRLTEEQ+ NFRQEVDGKGL SYPHP LMP+FW
Sbjct: 123 PTEEHGGDLIYYQGHASPGIYARAFLEGRLTEEQMLNFRQEVDGKGLSSYPHPHLMPDFW 182

Query: 187 QFPTVSMGLGPISAIYQARFLKYLNGRGLKDTTAQRVYAFLGDGEMDEPESRGAISFAAR 246
           QFPTVSMGLGPI+AIYQARF+KYL  RG      QRV+ F+GDGE DEPE+ GAIS A R
Sbjct: 183 QFPTVSMGLGPITAIYQARFMKYLENRGFIPKGKQRVWCFIGDGECDEPETLGAISLAGR 242

Query: 247 EKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKLLAKDTT 306
           E LDNL F+INCNLQRLDGPV GNGKIIQELEG+F+GA WNV KV+WG  WD L A D  
Sbjct: 243 ENLDNLVFVINCNLQRLDGPVRGNGKIIQELEGVFKGANWNVNKVVWGRLWDPLFAVDED 302

Query: 307 GKLLQLMNETIDGDYQTFKAKDGAYVREHFFGKYPETAALVADMTDDEIFALKRGGHESS 366
           G++ + M++ IDG+YQ +KAKDGAYVR+HFFG  PE    V  M+D+E++ L RGGH+  
Sbjct: 303 GRMQRRMDQAIDGEYQNYKAKDGAYVRKHFFGADPELLKRVESMSDEEVWKLNRGGHDPY 362

Query: 367 KLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMRNRLGLQ 426
           K+YAA+  A   KG+PTVILA T+KGYG G A E KNIAH  KK+D+  +   R+R  + 
Sbjct: 363 KVYAAYHQAVHHKGQPTVILAHTIKGYGTG-AGEAKNIAHNTKKVDIDSLKKFRDRFDIP 421

Query: 427 DLISDEEVKNLPYLKLEEGSKEFEYLHARRKALHGYTPQRLPNFTGEFIVPALEDFKPLL 486
             ++D +++ LP+ +  E S E +YL   R  L G+ PQR P  +     P L+  K +L
Sbjct: 422 --VNDSQLEELPFYRPAEDSAEMKYLRKCRDKLGGHLPQRRPK-SFSIPTPPLDTLKAVL 478

Query: 487 E-EQSREISSTMAYVRSLNILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYNPHGQN 545
           +    REIS+TMA+ R L+ L+KDK++G+ IVPI+ADEARTFGMEG+FRQ+GIY+P GQ 
Sbjct: 479 DGSGDREISTTMAFGRILSQLVKDKDLGKRIVPILADEARTFGMEGMFRQLGIYSPVGQL 538

Query: 546 YTPQDRDIVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYIYYSMFGF 605
           Y P DRD V YY+E   GQ+LQEG+NE GA SS++AA T+YS  N PM+P YI+YSMFGF
Sbjct: 539 YEPVDRDQVMYYREEKDGQILQEGLNEAGAFSSFIAAGTAYSNYNQPMLPVYIFYSMFGF 598

Query: 606 QRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCISYDPTFAY 665
           QR+GD+AW AGD Q RGFLLG T+GRTTLNGEGLQHEDGHSHILA T+PNC SYDPT+ Y
Sbjct: 599 QRIGDLAWAAGDAQTRGFLLGGTSGRTTLNGEGLQHEDGHSHILASTIPNCRSYDPTYGY 658

Query: 666 EVAVILQDGIRRMYGEQENVFYYLTLMNESYAHPAMPAGAEEGIRKGIYKLETHAGN-KA 724
           E+AVI+  G+  M  +Q++V+YY+T+MNE+Y  PAMP G E+GI KG+Y LE   G+ K 
Sbjct: 659 ELAVIMHHGMHEMMEQQKSVYYYITVMNENYQQPAMPQGVEDGIIKGMYLLEEAKGDFKH 718

Query: 725 KVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNMLHPEAEVK 784
           +VQL+ SGTI+ EVR A  IL+ + GV +DV+SVTSFNEL RDG A DR+N LHP  E +
Sbjct: 719 RVQLLGSGTILREVRAAVDILA-KMGVGADVWSVTSFNELRRDGLAIDRWNRLHPTEEPR 777

Query: 785 VPYIAQVM-GTE-PAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSDSRENLRRHFE 842
             Y+ Q + G E P IA+TDYMK +ADQ+R ++P++ Y+VLGTDGFGRSDSR  LR  FE
Sbjct: 778 KSYVQQCLEGREGPVIASTDYMKLFADQIRQWVPSREYQVLGTDGFGRSDSRAKLRDFFE 837

Query: 843 VNAGYVVVAALNELAKRGEVEKSVVAAAIKKFDIDTEKTNPL 884
           V+  +V VAAL  LA RG +E++VVA AI +F ID EK NPL
Sbjct: 838 VDRRWVTVAALQALADRGAIERTVVANAITEFGIDPEKRNPL 879