Pairwise Alignments

Query, 886 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Vibrio cholerae E7946 ATCC 55056

Subject, 784 a.a., pyruvate dehydrogenase E1 component from Caulobacter crescentus NA1000

 Score =  137 bits (345), Expect = 3e-36
 Identities = 201/805 (24%), Positives = 317/805 (39%), Gaps = 62/805 (7%)

Query: 78  RRIRSIIRWNAIMIV-----LRASKKDLELGGHMASFQSSAAFYETCFNHFFRAPNEKDG 132
           RR+   I W A   +     LR S+  L++GGH AS  S        +    R       
Sbjct: 17  RRLEERILWLAAWTIHNANHLRESRDGLKVGGHQASSASLTTIMTALYMKALRPQ----- 71

Query: 133 GDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPKLMPEFWQFPTVS 192
            D V  + H SP  +A   + GR   + LDN ++     G  SYP      +   F T S
Sbjct: 72  -DRVAVKPHASPVFHAIQHLFGR---QSLDNLKRFRALGGAQSYPSRTKDVDDVDFSTGS 127

Query: 193 MGLGPISAIYQARFLKYLNGRG-LKDTTAQRVYAFLGDGEMDEPESRGAISFAAREKLDN 251
           +GLG     + +    YL  RG +K     R+ + LGD E+DE     A+  A +  + N
Sbjct: 128 VGLGVAMTAFASLTQDYLAARGAVKPEKMGRMISLLGDAELDEGNIYEALIEACKHDIRN 187

Query: 252 LCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKLLAKDTTGKLLQ 311
             ++++ N Q LD       ++      +F  AGW V  + W     +  A+   G  LQ
Sbjct: 188 TWWIVDYNRQSLDATT--QDRMFTRYGEIFEAAGWAVETLKWSRRQREAFAR-PGGDKLQ 244

Query: 312 LMNETIDGD-YQTFKAKDGAYVREHF---FGKYPETAALVADMTDDEIFAL--KRGGHES 365
              ET   D +     + GA  RE         PE  AL+A   D ++  L  + GGH  
Sbjct: 245 AWIETAPNDLFSALTYQGGAAWRERLTADLADSPEALALIAAYKDVDLAELMTELGGHCL 304

Query: 366 SKLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMRNRLGL 425
             L  AF+ A     RP   +A TVKG  +       N A     M    +  +R RLG 
Sbjct: 305 ETLLEAFEKASQ-DDRPRFFIAYTVKGLRLPFQGHKDNHA---GLMTPAQIAELRARLG- 359

Query: 426 QDLISDEEVKNLPYLKLEEGSKEFEYLHAR----RKALHGYTPQRLPNFTGEFIVPALED 481
             ++  EE   L  L   E +   + L AR     +    +   ++P  +   ++ A+  
Sbjct: 360 --VVEGEEWDPLSGLSAAERT-AIKGLVARAPFAAEVERNHLAPQIPTPSASELLAAVAG 416

Query: 482 FKPLLEEQSREISSTMAYVRSL-NILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYN 540
                     + S+  A+ + +  I  +       +V    D   +  + G   + G++ 
Sbjct: 417 --------GGDQSTQAAFGKVMFEIAARKDEFAGRVVTTSPDVTVSTNLGGFVNRRGVFQ 468

Query: 541 PHGQNYTPQDRDIVS--YYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYI 598
               +   + R I S   + +A +GQ ++ GI E     +  A   +       + P   
Sbjct: 469 RRAHDDVFKRRRIPSAQVWSKAETGQHVELGIAENNLFIALAALGLTAPLFGERLFPVGT 528

Query: 599 YYSMFGFQRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCIS 658
            Y  F   R  D    A  Q AR FLL AT    TL  EG  H+  ++ ++    P   +
Sbjct: 529 LYDPF-IARGLDALNYACYQDAR-FLLVATPSGLTLAPEGGAHQSINAPVIGMAQPGLDT 586

Query: 659 YDPTFAYEVAVILQDGIRRMYGEQENVFYYLTLMNESYAHPAMPAGA-EEGIRKGIYKLE 717
           Y+P FA E AV++     R+   ++    YL L   +   P     A  +G+  G Y L 
Sbjct: 587 YEPAFADETAVLMAHAFERIQA-KDGASTYLRLSTRAIPQPDRTGEAWRQGVIDGGYWLR 645

Query: 718 THAGNKAKVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNML 777
             A   A++ +  SG +  E   A + L+E+   A  + +VTS + L RD  A  R    
Sbjct: 646 APA-RGARLAIAYSGALAPEALAAFEALAEDMPEAG-LLAVTSADLLHRDWTASGRARWT 703

Query: 778 HPEA-----EVKVPYIAQVMGTEPAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSD 832
              A     E  +  +AQ  G            ++   VR     Q  + LG + FG+S 
Sbjct: 704 GEGARTSTIETLLAPLAQGAGLVTLTDGAPLALSWLGSVR----GQRVRALGLETFGQSG 759

Query: 833 SRENLRRHFEVNAGYVVVAALNELA 857
              +L   + ++A  V+ A  + LA
Sbjct: 760 DLPDLYAKYRLDADAVLDACADLLA 784