Pairwise Alignments

Query, 563 a.a., AMP-dependent synthetase from Vibrio cholerae E7946 ATCC 55056

Subject, 554 a.a., AMP-dependent synthetase and ligase (RefSeq) from Shewanella sp. ANA-3

 Score =  539 bits (1388), Expect = e-157
 Identities = 272/551 (49%), Positives = 379/551 (68%), Gaps = 7/551 (1%)

Query: 15  ALPPPNEMLLRWAKERPNEVYLKQIINRQFVEFTYAEVADKALRLVSALRALGADPGDKV 74
           A+  P EML  WA  R +E+YL+Q I  Q+++FT+ EV +K  +L  ALR LG +PGDK+
Sbjct: 4   AIKTPVEMLAHWANTRGDEIYLRQPIKGQYLDFTWNEVQEKVQQLAGALRHLGLEPGDKI 63

Query: 75  ALISKNCAEWFICDLAMMLGDYISVPIFPTAGSETIDYCLEHSESKILIVGKLDD-NKAT 133
           A++SKNCAEWFI DLA+M G YISVPI+PTA ++TI Y L+HS +K + +GKLD      
Sbjct: 64  AVLSKNCAEWFITDLALMHGGYISVPIYPTANTDTIRYVLQHSGAKAIFLGKLDHWADQE 123

Query: 134 AHVLAERPNLISISLPYPSAAKCQYEFQTLIKQHQPSEERPTHFDEKLMSIVYTSGTSGQ 193
           A V  E   L+ +++PY +    QY+++ L+K   P  E P    ++ M+++YTSG++GQ
Sbjct: 124 AGVGGE---LLRLAMPYETMP-AQYQWEQLLKMGNPLIEAPLPELDQTMTLIYTSGSTGQ 179

Query: 194 PKGAMLTYGAFTWSAQQLINHIGIEENDRLFSYLPLAHITERVYIFGSSIIGGVLTAFPE 253
           PKGA+ T+ ++ W+ Q ++  +    NDRL SYLPLAHITERV I GSS   G   AF E
Sbjct: 180 PKGAIQTFASYGWTCQAVVRDLRTNGNDRLLSYLPLAHITERVAIEGSSFYSGSTVAFVE 239

Query: 254 SLDTFIEDVKMHRPTLFISVPRLWTLFQQRIQDKLPQKKLNILLKIPFVNSLIKRKLADG 313
           SLD+F+ DV+  +PT+F SVPRLW+LFQ+ I DK+   KLN+LLKIP ++SL+K K+  G
Sbjct: 240 SLDSFVADVQRAKPTVFFSVPRLWSLFQKNIIDKIGVGKLNLLLKIPLISSLVKHKIHKG 299

Query: 314 LGLDQARVLGCGSAPVSPALLEWYRSVGLNITEAWGMTESFAYSTLNYPFRADKIGTVGN 373
           LGL+  R+LG GSAP+ P+L+ WY S+GL+I EAWGMTE+ AYS +NYPF   KIGTVG 
Sbjct: 300 LGLNHCRLLGSGSAPIPPSLIHWYHSIGLDICEAWGMTENCAYSIINYPFDVRKIGTVGK 359

Query: 374 AGPGIELKIAEDEEILVRSKGLFAGYYKNDTATAESFNDDGWLHTGDIGSLDSEGYLTIQ 433
                +++  ED E+L++S GL   YY    ATA +F+ DG+ HTGD+ ++D++G +TI 
Sbjct: 360 PVQDCQIRQGEDGELLLKSPGLMTAYYLQPEATAAAFDPDGFFHTGDLCAIDADGCVTIT 419

Query: 434 GRKKDTFKTAKGKFVAPVPIEKKLFEYSRVEMMCLIGSGLPAPILLAVPHNFPHFDRARY 493
           GR KD FKTAKGK+VAPVPIE+KL +   VE++C+IGSGLP P+ L              
Sbjct: 420 GRVKDNFKTAKGKYVAPVPIERKLAQDPHVELICVIGSGLPHPVALVQLSEGATLQAREE 479

Query: 494 ERTTQK-VIARINSELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRHVLEKKYHDVGQN 552
            RT+ K  +  +N  LESHE +  ++++ +PW+I+N +LTPTLKIKRHVLEK + +   +
Sbjct: 480 VRTSLKATLDSVNPHLESHEHVDAIVVVNEPWTIENDVLTPTLKIKRHVLEKAFSE-RVD 538

Query: 553 WPKGQLVVWEE 563
             +G  V WE+
Sbjct: 539 GIRGAQVRWED 549