Pairwise Alignments

Query, 369 a.a., bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II from Vibrio cholerae E7946 ATCC 55056

Subject, 409 a.a., 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (TIGR) from Desulfovibrio vulgaris Hildenborough JW710

 Score =  340 bits (872), Expect = 4e-98
 Identities = 190/374 (50%), Positives = 254/374 (67%), Gaps = 8/374 (2%)

Query: 1   MPISTPQEIIEDIRQGKMVILMDDEDRENEGDLIMAAEHITPAAINFMATHGRGLICLTL 60
           M I   +E I+ IR+G+M+IL+DDEDRENEGDL +AA+H+TP  INFMATHGRGLICL L
Sbjct: 1   MSICKAEEAIDAIRKGEMIILVDDEDRENEGDLTIAAQHVTPEVINFMATHGRGLICLAL 60

Query: 61  TKERCRRLGLNPMVQDNNAQYTTNFTVSIEAAEGVTTGISAADRARTVQAAVAKEAKAAD 120
           + E   +L L  M + N +++ TNFTVSIEA  GVTTGISAADRA T+  AVA + KA D
Sbjct: 61  SPEWVDKLQLPLMARRNESKFGTNFTVSIEARRGVTTGISAADRATTILTAVADDVKAED 120

Query: 121 LVQPGHIFPLAAQDGGVLTRAGHTEAGCDLARLAGLEPASVIVEILNDDGTMARRPDLEV 180
           +V PGHIFPL AQ GGV+ RAG TE   DLA+LA L+PA+VI EI+ +DG MAR PDL  
Sbjct: 121 IVTPGHIFPLRAQKGGVMVRAGQTEGSVDLAKLANLKPAAVICEIMREDGEMARMPDLIE 180

Query: 181 FAEKHGLKLGTIADLIEYRNHTE-TTIERVAQCKLPTEYGEFELVTYRDIIDKQIHFALR 239
           FAEKH +K+ TI DLI YR  +   +++RV + K+PT YG+F+++ Y + +  + H AL 
Sbjct: 181 FAEKHNMKIATIKDLIRYRMQSGLLSVKRVGEAKMPTRYGDFQIIAYENELHDETHIALV 240

Query: 240 KGDIT-SAPTLVRVHLQDTFTDLLHSNRAAERSWPLATAMQRIGQEG-GVLVILGHEESS 297
           KGDI+ S P LVRVH +    D+L S R  +    LA A+ +I  +G GVL+ +  E   
Sbjct: 241 KGDISPSEPVLVRVHSECLTGDVLGSLR-CDCGGQLAAALCQIAAKGSGVLLYMRQEGRG 299

Query: 298 ELLLHRVKMFELQDKG----EAPAMAKKQGTSRRVGVGSQILADLGVKEMRLLSSPNKKY 353
             L +++K + LQD+G    EA      +   R  G+G+QIL DLGV++MR++++  KK 
Sbjct: 300 IGLGNKIKAYGLQDQGYDTVEANHKLGFKADLRDYGIGAQILVDLGVRKMRMMTNNPKKI 359

Query: 354 HALGGFGLNVVEYV 367
             L G+G+ VVE V
Sbjct: 360 VGLEGYGIEVVERV 373