Pairwise Alignments

Query, 369 a.a., bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II from Vibrio cholerae E7946 ATCC 55056

Subject, 400 a.a., GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase from Caulobacter crescentus NA1000

 Score =  295 bits (755), Expect = 1e-84
 Identities = 178/369 (48%), Positives = 228/369 (61%), Gaps = 10/369 (2%)

Query: 3   ISTPQEIIEDIRQGKMVILMDDEDRENEGDLIMAAEHITPAAINFMATHGRGLICLTLTK 62
           +S   E +  ++ G M++L+DDEDRENEGDL+MAAE    AAI FMA    GLICLTL  
Sbjct: 1   MSRLSEALTRLKAGGMIVLVDDEDRENEGDLVMAAEFADAAAIAFMAKRASGLICLTLEA 60

Query: 63  ERCRRLGLNPMVQDNNAQYTTNFTVSIEAAEGVTTGISAADRARTVQAAVAKEAKAADLV 122
           E   RL L PMV DN     T FTVSIEAA GV TGISA DRART+ AA+A +A+AADLV
Sbjct: 61  ETIDRLCLAPMVSDNRTSRQTAFTVSIEAATGVDTGISAFDRARTIAAAIAPDAQAADLV 120

Query: 123 QPGHIFPLAAQDGGVLTRAGHTEAGCDLARLAGLEPASVIVEILNDDGTMARRPDLEVFA 182
            PGH+FPL A+ GGVL R GHTEA  DL R+AGL PA VI EI+ DDG+MARRPDLEVF 
Sbjct: 121 SPGHVFPLRARPGGVLVRNGHTEASVDLMRMAGLRPAGVICEIMKDDGSMARRPDLEVFC 180

Query: 183 EKHGLKLGTIADLIEYRNHTETTIERVAQCKLPTEYG--EFELVTYRDIIDKQIHFALRK 240
            +H L L TIA+L+ +R  TE  ++ VA  +LP+++    F +  +R  ID   H A+  
Sbjct: 181 REHDLPLLTIAELVAHRKATELLVDEVAAARLPSDHAGQAFSVRAFRSRIDGGEHLAMVA 240

Query: 241 GDITSAPTLVRVHLQDTFTDLLHSNRAAERSWPLATAMQRIGQEG-GVLVILGHEESSEL 299
           G +T AP LVRVH +    D L S R  +    L  ++++I   G G L+ L + E   L
Sbjct: 241 GPLTGAP-LVRVHSECLTGDALGSRR-CDCGEQLRESLRQISDSGNGALIYLRNHEGRGL 298

Query: 300 -LLHRVKMFELQDKGEAPAMAKK----QGTSRRVGVGSQILADLGVKEMRLLSSPNKKYH 354
            L +++  + LQD+G     A          R  GV +QIL  LGV E++LLS+  +K  
Sbjct: 299 GLANKIAAYALQDQGLDTVQANHALGFADDQRDYGVAAQILRALGVGEVKLLSNNPRKAA 358

Query: 355 ALGGFGLNV 363
            L   G+ V
Sbjct: 359 GLRANGVTV 367