Pairwise Alignments

Query, 761 a.a., 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase from Vibrio cholerae E7946 ATCC 55056

Subject, 756 a.a., 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) from Shewanella sp. ANA-3

 Score =  827 bits (2135), Expect = 0.0
 Identities = 426/752 (56%), Positives = 532/752 (70%), Gaps = 7/752 (0%)

Query: 7   LGYPRIGEKRELKFALEKYWRGEIDQAALKQVGSQIRQKNWALQKEAGLDFVTAGDFAWY 66
           LG+PRIG +RELKFALEKYWRGE  QA L +V  ++R+ +W  Q  AG++ V  GDFA+Y
Sbjct: 6   LGFPRIGRRRELKFALEKYWRGESTQAELHEVAKELRRTHWQWQVAAGIEQVPVGDFAFY 65

Query: 67  DHVLTTTLLLGHVPKRH-SHGFPDLDTLFRVGRGQSQNACGCGTGSAASDMTKWFNTNYH 125
           D VLT +  L  +P RH   G  DLDTLFRV RG++      GT + AS+MTK+FNTNYH
Sbjct: 66  DQVLTLSATLNAIPDRHRGEGAIDLDTLFRVARGRAPT----GTDAPASEMTKYFNTNYH 121

Query: 126 YIVPEFSSNDTFNVSWPQLFEEVNEALQAGHDVKPVLLGPISYLYLGKEVEEGFDRLTLL 185
           Y+VPE   +  F++++ Q F+EV EA   G+  KPVLLGP+SYLYL K V + FD+L+LL
Sbjct: 122 YLVPELKQDQVFSIAYEQFFDEVAEAQALGYQAKPVLLGPVSYLYLAKTVGQDFDKLSLL 181

Query: 186 PRLLTAYQAILSKLAKQGVQWVQIDEPILALELEPRWQEAFKLAYQVIR-GDVKLLLTTY 244
           P LL AY  IL++ A QGV WVQ++EPILALEL   WQ A   AYQ ++   VK+LLT+Y
Sbjct: 182 PNLLKAYADILARFAAQGVTWVQLEEPILALELTHDWQAAISEAYQALKTAQVKILLTSY 241

Query: 245 FDSVLDTLDKIVELPVDGLHVDISAAPAQLETIVNRLPSDWVLSAGVINGRNVWRADLSA 304
           + S+      +  LPV GLH+D+  AP QL    N L SD +LSAGV+NGRNVW A++  
Sbjct: 242 YGSISHHQALVSALPVAGLHLDLVTAPEQLALFANALRSDQILSAGVVNGRNVWAAEVDL 301

Query: 305 ILARLQPVKTLLGERLWVASSCSLLHSPVDLDLEGDLSAETRSWFAFAKQKVTEVALLGR 364
           I+ R+  V   LG RLW+ +SCSLLHSPVDL++E  L+   R   AFAKQK+ E+A + +
Sbjct: 302 IVERIGSVARDLGARLWIGTSCSLLHSPVDLEVETTLTPALRQQLAFAKQKLLELANVRQ 361

Query: 365 ALEGDAAAILACDTYSQPIVARKSSHIVNKASVQTRINNITAALAERSAPYIERAHHQAE 424
            L+   + I A +  +  +  R++      A V  R+  +T A  ER + + ER   Q  
Sbjct: 362 LLQAPES-IAAKEIVNTCLARREAKAQAADAKVIARVAALTQADYERVSEFTERQAVQQR 420

Query: 425 VLGLPFLPTTTIGSFPQTGEIRTERSAYRQGKLSEQEYVQALKGHIADAVKRQEALGLDV 484
              LP LPTTTIGSFPQT  IR  RS +R+G+LS+ +Y + L+    D + RQ  LG+DV
Sbjct: 421 KYRLPLLPTTTIGSFPQTPAIRGLRSRWRKGELSDAQYTEQLQQVTRDTIDRQLKLGIDV 480

Query: 485 LVHGEAERNDMVEYFAENLAGFQTTQFGWVQSYGSRCVKPAIVVADIEREKPITVEWSTY 544
           LVHGEAERNDMVEYF E L G   T+ GWVQSYGSRCVKP ++  D+ R K +TV+W+ +
Sbjct: 481 LVHGEAERNDMVEYFGEQLEGVGFTKNGWVQSYGSRCVKPPLIYGDVSRPKAMTVDWAEF 540

Query: 545 AQSLTSKQMKGMLTGPVTILCWTFPREDISRQEIAQQLALALRDEVADLQDAGINIIQID 604
           AQSLT K +KGMLTGPVTIL W+F REDISR  IA QLALA+RDEV DLQ+AGI IIQID
Sbjct: 541 AQSLTDKPVKGMLTGPVTILHWSFAREDISRDTIATQLALAIRDEVVDLQNAGIGIIQID 600

Query: 605 EPAIREGLPLKKRDHQTYLDWAVQAFKISAGSARPETQIHTHMCYSEFNEIIESVAALDA 664
           EPA REGLPLK+ + Q YLDWAV AFK+SA     ETQIHTHMCYSEFN+ I ++AA+DA
Sbjct: 601 EPAFREGLPLKQSEWQAYLDWAVNAFKLSAAGVVDETQIHTHMCYSEFNDTIAAIAAMDA 660

Query: 665 DVITIETSRSNMELLKAFEEFNYPNEIGPGVYDIHSPNIPAQAWIEDLLRKAAEKIPAQR 724
           DVITIETSRS MELL AFE+F YPNEIGPGVYDIHSPN P+   +  L+ KAA+K+P ++
Sbjct: 661 DVITIETSRSRMELLNAFEDFEYPNEIGPGVYDIHSPNTPSVEAMVHLIEKAAQKVPVRQ 720

Query: 725 LWVNPDCGLKTRNWPEVEAALTNMVNAAKALR 756
           LWVNPDCGLKTR W EVE AL NMV+A + LR
Sbjct: 721 LWVNPDCGLKTRTWDEVEPALKNMVDATRELR 752