Pairwise Alignments

Query, 1037 a.a., AcrB/AcrD/AcrF family protein from Vibrio cholerae E7946 ATCC 55056

Subject, 1014 a.a., Cation/multidrug efflux pump from Pseudomonas stutzeri RCH2

 Score =  830 bits (2143), Expect = 0.0
 Identities = 444/1012 (43%), Positives = 637/1012 (62%), Gaps = 6/1012 (0%)

Query: 23   AAYFINNRVISWMVSLIFLIGGTAAFFNLGRLEDPAFTIKDAMVVTSYPGATPQQVEEEV 82
            A Y I   V  W++ LI L GG  AFF +GRLEDP FTIK A+V   YPGAT  +VE++V
Sbjct: 4    ARYSITRPVNIWILVLICLFGGILAFFEIGRLEDPEFTIKQAIVNVQYPGATALEVEQQV 63

Query: 83   TYPLEKAIQQLTYVDEVNSISSRGLSQITVTMKNNYGPDDLPQIWDELRRKVNDLKGALP 142
            T PLE AIQQ++ + E+ S S  G+++I V M++ Y  D LPQIWDELR K+ND +G LP
Sbjct: 64   TEPLESAIQQMSQIKEIRSRSMPGIAEIRVEMQDRYAGDALPQIWDELRNKINDAQGDLP 123

Query: 143  PGVNPPLVIDDFGDVYGILLAVTGEGYSYKELLDYVDYLRRELELIDGVSKVSVSGQQQE 202
            PG+ PP V DDFGDVYGI  A+TG+G + KEL +    LRR L   DGV KV ++G Q+E
Sbjct: 124  PGIEPPQVNDDFGDVYGIFYALTGDGLTLKELHETAKDLRRALLTADGVGKVEIAGVQEE 183

Query: 203  QVFIEISMKRISTLGISPQTVFNLLSTQNLVSDAGAIRIGSEYIRIHPTGEFDDVEKLGD 262
            ++ +E+   +++ LG++P  +   L+  +   DAG +  G  ++R+ P+G FD +E+L  
Sbjct: 184  RILVEVDQAQLAALGVAPDEIAAALADTDAAVDAGGVNAGEFFVRLRPSGAFDSLEELRA 243

Query: 263  LILSERGAQGLIYLRDVAEVKRGYVEVPSNVITFNGKLALNVGVSFAQGVNVVEVGQRFD 322
            L + + G Q  + L  +A + R Y E P  +I  NG+ AL +G+S   G N+VEVG   +
Sbjct: 244  LPVGQ-GPQ-RVELGAIARLSREYAERPQQIIRHNGQQALTLGISGVSGANIVEVGHSVE 301

Query: 323  RRLAELKYQQPIGIDIAEVYSQPKEVDKSVSGFVVSLGQAVAIVIIVLLFFMGLRSGLLI 382
              L   +++ P+G D+  +Y Q + VD+SV+ F +++  +VAIV+ VL   MGLR+G +I
Sbjct: 302  AVLQANEHRMPLGADLHPLYEQHQIVDESVNSFALNVFLSVAIVVGVLCIAMGLRAGFII 361

Query: 383  GLILLLTVLGTFIFMQYFKIDLQRISLGALVIALGMLVDNAIVVVEGILIGTQKGRTRLQ 442
            G +L LTVLGT + M    I+L+RISLGAL+IA+GMLVDNA+VV +G+L+  ++G++ L+
Sbjct: 362  GAVLFLTVLGTLLVMWLVGIELERISLGALIIAMGMLVDNAVVVCDGMLVRQRQGKSILE 421

Query: 443  AATDIVTQTKWPLLGATVIAVTAFAPIGLSEDATGEYCGTLFTVLLISLMLSWFTAISLT 502
            A+   + QT+WPLLGAT+I + AFA IGLS+D TGE   +LF V+ +SL+LSW  A+ L 
Sbjct: 422  ASQQTLRQTQWPLLGATIIGILAFAGIGLSQDTTGELLFSLFFVIAVSLLLSWLLALLLV 481

Query: 503  PFFADLFFRGQKAPASGEESDPYQGFIFVVYRRFLEFCMRRAWLTMGVLVLGLAASLYGF 562
            P F     R   A    +    Y G  +  YRR     + R WLT+GVL++    S   F
Sbjct: 482  PLFGHYLLR--NADTDEDPDAAYNGPWYNRYRRLAGGVLHRPWLTIGVLLVLTVVSAVIF 539

Query: 563  TKVKQAFFPSSTTPMFMVDVWMPEGTDIRATDAILLELEKWLSAQESVDSVTTTAGKGLQ 622
            T++ Q+FFP S+TP+F V++++P+GT IR T     ++E++L+  E V  V++  G G  
Sbjct: 540  TRLPQSFFPPSSTPLFYVNLFLPQGTHIRDTARTASDVEEYLAEMEGVSGVSSFIGAGAS 599

Query: 623  RFMLTYSPEKSYAAYGEITTRVTDYQQLAALMARFRAHLDARYPQINYKLKQIELGPGGG 682
            RFMLTY PE+  ++      R  D + +  L+ +    L  RYP  +    Q   GP   
Sbjct: 600  RFMLTYMPEQPNSSLMHFLVRTEDAELIDRLVRQINQELPQRYPSADVTAAQFMFGPNAE 659

Query: 683  AKIEARIVGSDPTVLRSIAAQVMDVMYADPGAYNIRHDWRERTKVLEPQFNESQARRYGI 742
            AK+EARI G D  VLR+I+A+    +  +   +N+R DWR+   VL PQ    +    G+
Sbjct: 660  AKLEARISGPDIEVLRAISAEGRKRLQDEGKVFNVRDDWRQPVLVLRPQLALDRLADAGL 719

Query: 743  TKADVDEFLAMSFSGKTIGVYRDGTTLMPIVARLPEEERVDIRNIEGMKIWSPALSEYIP 802
            T+  V   LA    G+ + + R+   L+P++ R   E+RV   ++    IWSPA + Y+P
Sbjct: 720  TRQAVARALAAGSEGQRVSLLRERDELIPVLLRAAPEDRVSSDDLLQRLIWSPAGNGYVP 779

Query: 803  LQQVTLGYEMRWEDPLIVRKNRKRMLTVMADPDLLGEETAATLQQRLQPQIEAIPLPPGY 862
            L QV  G E   ED +IVR +R+R +++ A+P     E      QR++P IE I LP  Y
Sbjct: 780  LAQVADGIEPTSEDSIIVRYDRERTISIRAEP--RDGENTNEAHQRIRPLIEGIELPVNY 837

Query: 863  FLEWGGEYESSGDAKASLFKTMPLGYLFMFLITVFLFNSVKESLIVWLTVPLAVIGVTTG 922
             L+WGG+YE S DA+ +L  T+ + YL M L+TV LF  V++ L++WL VP+A+ GV+ G
Sbjct: 838  SLKWGGDYEQSSDAQQALASTLAVPYLAMVLVTVLLFARVRQPLMIWLVVPMAICGVSFG 897

Query: 923  LLALNTPFGFMALLGFLSLSGMLLKNGIVLLDQIEIEMHSGKDPYLAVVDASLSRVRPVC 982
            LL     FGFMALLG LSL+GML+KN +VL+D+I+ ++        A+++AS SR+RPV 
Sbjct: 898  LLLTGQAFGFMALLGLLSLTGMLIKNAVVLVDEIDRQIDDEVPRLTAIIEASASRLRPVM 957

Query: 983  MAAVTTILGMIPLLPDIFFRPMAVTIMFGLGFATVLTLIVVPVLYRLFHHVK 1034
            MAA TT+LGM+PLL D FF  MAVTIM GLGFAT+LTL+ VP LY LF  V+
Sbjct: 958  MAAGTTVLGMVPLLFDPFFANMAVTIMGGLGFATLLTLLAVPCLYLLFMKVR 1009