Pairwise Alignments

Query, 457 a.a., multidrug resistance protein NorM from Vibrio cholerae E7946 ATCC 55056

Subject, 466 a.a., Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog from Pseudomonas fluorescens FW300-N2E2

 Score =  211 bits (538), Expect = 3e-59
 Identities = 140/451 (31%), Positives = 218/451 (48%), Gaps = 12/451 (2%)

Query: 2   HRYKKEASNLIKLATPVLIASVAQTGMGFVDTIMAGGVSAIDMAAVSIAASIWLPSILFG 61
           H  + E   L++LA P++ + +A   M   DT+M   +S   +A   + A+ +    +F 
Sbjct: 5   HPVRTELWALLRLAGPLIASQLAHMLMVLTDTVMMARLSPEALAGGGLGAATYSFVSIFC 64

Query: 62  VGLLMALVPVVAQLNGAGRQHKIPFEVHQGLILALLVSVPIIAVLFQTQFIIRFMDVEEA 121
           +G++ A+  +VA   GAG           GL LA L+++    +L+  + ++      E 
Sbjct: 65  IGVIAAVGTLVAIRQGAGDVEGATRLTQAGLWLAWLMALMAGLLLWNLKPVLLMFGQTET 124

Query: 122 MATKTVGYMHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGK 181
                  ++ A+ FA+P YL F ALR FT  +    P MVI   G + N  LN+  + G 
Sbjct: 125 NVLSAGQFLLALPFALPGYLSFMALRGFTSAIGRATPVMVISLGGTVANFLLNYALITGM 184

Query: 182 FGAPELGGVGCGVATAIVYWIMLLLLLFYIVTSKRLAHVKVFETFHKPQPKELIRLFRLG 241
           FG P+LG +G G+ TAIV   M L L ++I          + E   +P  + L  L+RLG
Sbjct: 185 FGLPKLGLMGIGLVTAIVANCMALALAWHIHRHPAYRAYPLLEGLSRPNRQYLKELWRLG 244

Query: 242 FPVAAALFFEVTLFAVVALLVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVGHK 301
            P+      EV LFA  AL +  +GST +AAHQ+AL   S+ FM P  +  A+++R+G  
Sbjct: 245 LPIGGTYAVEVGLFAFAALCMGTMGSTSLAAHQIALQIVSVAFMVPAGMSYAITMRIGQH 304

Query: 302 LGEQDTKGAAIAANVGLMTGLATACITALLTVLFREQIALLYTEN-----QVVVALAMQL 356
            G      A +A  VG+  G A     A++  L   Q+  L+ ++     + V+ LA+ L
Sbjct: 305 YGAGQLLMARLAGRVGIGFGAAAMLAFAMVFWLLPHQLVGLFLDHDDPAFRDVINLAVSL 364

Query: 357 LLFAAIYQCMDAVQVVAAGSLRGYKDMTAIFHRTFISYWVLGLPTGYILGM-TNWLTEQP 415
           L  AA ++  D  Q +A G +RG KD    F      YW++G P  + +    NW     
Sbjct: 365 LAVAAWFELFDGTQTIAMGCIRGLKDAKTTFLVGLGCYWLIGAPAAWWMAFHLNW----- 419

Query: 416 LGAKGFWLGFIIGLSAAALMLGQRLYWLQKQ 446
            G  G W G  +GL+ AA+ L     W  K+
Sbjct: 420 -GPTGVWWGLALGLACAAVSLTAAFEWKMKR 449