Pairwise Alignments

Query, 951 a.a., formate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 1021 a.a., formate dehydrogenase, alpha subunit, proteobacterial-type from Pseudomonas stutzeri RCH2

 Score =  231 bits (590), Expect = 1e-64
 Identities = 181/664 (27%), Positives = 294/664 (44%), Gaps = 131/664 (19%)

Query: 19  ISRRAFMKNTSLAAGGAAVGASLFTPGMIRKAQASEVD-RSAKTEVKRTICSHCSVGCGI 77
           +SRR F+K  +   G +++    F P    +A AS    +    +V R IC++CSVGCG+
Sbjct: 5   VSRRQFLKFGAAGLGASSMAMMGFAP---EEALASVRHFKLTGAKVTRNICTYCSVGCGM 61

Query: 78  YAEVQ-NGVWTGQEPAF------DHPFNAGGHCAKGAALREHGHGERRLKYPMKLEGG-- 128
               + +G     +  F      DHP + G  C +GA + +    + R++YP   E G  
Sbjct: 62  LLYARGDGAINSHDHIFHVEGDPDHPVSRGSLCPRGAGVLDFIKSDSRVRYPQVREPGTD 121

Query: 129 KWKKISWEQAINEIG-------DKALKIREESGP-----DSVYFLGSAKHSNEQAYLFRK 176
           +WK+ISW++A++ I        D+  +  ++ G       +   + ++  +NE AYL +K
Sbjct: 122 EWKRISWDEALDRIARLMKDDRDRNFETHDDEGQLVNRWMTTSMVAASACTNETAYLTQK 181

Query: 177 MASLWGTNNVDHQARICHSTTVAGVANTWGYGAMTNSFNDMHNCKSMLFIGSNPAEAHPV 236
           +    G   +D+QAR+ H  TVAG+A ++G GAMTNS+ D+ N   +L +G N AEAHPV
Sbjct: 182 ITRALGILKLDNQARVUHGPTVAGLAPSFGRGAMTNSWVDIRNANIILSMGGNSAEAHPV 241

Query: 237 AMQHILIAKEKNSCKIVVADPRRTRTAAKADYFVSLRPGSDVAFIWGVLWHVFKNNWEDK 296
             + ++ AKE++   ++  DPR  RT A ADY   +R G+D+ F+ G++  + +N+    
Sbjct: 242 GFRWVMQAKERSDAILISIDPRYNRTTAVADYHAWIRTGTDIVFLGGLISFLIENDRYAH 301

Query: 297 EYIRQRV---------------------------------FGMDE--------------- 308
           EY+                                     F +DE               
Sbjct: 302 EYVLHYTDAAHLVREGFEFNDGLFTGYDEERHQYDKATWNFDLDEQGFVRRDETLQHPRC 361

Query: 309 ----IRAEVAKWTPAEVERVTGVSEEEVYN----TAKTLAENRPGCVVWCMGGTQHTTGN 360
               +R   +++T   VERV G+ + +V       A++ A ++   +++ +G TQH+ G 
Sbjct: 362 VFQMMRKHYSRYTVEMVERVCGMPQAKVLQLWELLAQSAAPDKTMTILYALGWTQHSIGA 421

Query: 361 NNTRAYCILELALGNIGKSGGGANIFRGHDNVQGATDLGVLSDTLPGYYGLTEGS----- 415
              R   +++L LGN+G  GGG N  RGH N+QG TD+G+LS+ L GY  L         
Sbjct: 422 QMIRTGAMVQLLLGNMGMPGGGVNALRGHSNIQGLTDIGLLSNLLTGYMTLPAAGAQNYD 481

Query: 416 ------------------WKHW----ASVWGVDFEWIKNRFDQGTYNGALPMETPGIPVS 453
                             WKH+     S+    +       +   Y+    +  P   V 
Sbjct: 482 DYIKQKIRQPLLPNQVSYWKHYERFFVSMMKAFYGDAARAENNWCYDWLPKLSEPLYDVL 541

Query: 454 RWIDGVLENK--DNLQQRENIRAMFYWGHAVNSQTRGVEMKKAMQKLDMMVIVDPYPTVA 511
             ++ + + K      Q  NI A F             ++   + KL  +VI+DP  T  
Sbjct: 542 YAVNDMTKGKMTGAFCQGFNILAAF---------PNKAKVLDGLSKLKWLVIMDPLATET 592

Query: 512 AVM------------NDRTDGVYLLPATTQFETYGSVTASNRSIQWRDQVIEPLFESKPD 559
                          +     V+ LP TT  E  GS+T S+R +QW  Q   P  E+K D
Sbjct: 593 GEFWKNHGEFNDVDPSQIQTAVFRLPTTTFAEDDGSITNSSRWLQWHHQAAPPPGEAKTD 652

Query: 560 HEIM 563
             I+
Sbjct: 653 TAIL 656



 Score = 38.5 bits (88), Expect = 2e-06
 Identities = 52/207 (25%), Positives = 79/207 (38%), Gaps = 48/207 (23%)

Query: 763  WTFPDRVPLHREPLYTPRRDLLADYPTWDDQAFIFRVPTLYKSIQAQDKSV-----EYPI 817
            W      P H EPL +P    + + P   +    +  P     I  +D+       E+P 
Sbjct: 843  WLGEGPFPEHYEPLESP----IPNNPLHPNNPLAYHNPVA--RIFPEDRDTFGTFEEFPY 896

Query: 818  ILTSGRLVEYEGGGEETRSNPWL------AELQQEMFVEVNPKDANDLGFMDGDMVWVEG 871
              T+ RL E+         + W       A +Q E FVE+    A +LG   G+ V V  
Sbjct: 897  AATTYRLTEH--------FHYWTTHVLLNAIVQPEKFVEIGEVLAGELGIAAGEKVRVR- 947

Query: 872  AEKGRIKVKAMVTRRVKP--------GMAFLPFHFGGKFQGEDLRPKYPEGTQPYVVGEA 923
            +++G I   A+VT+R++P            +P H+G  F G   +               
Sbjct: 948  SKRGHIDAVAVVTKRLRPLQVDGRTVHQVGIPIHWG--FTGVARK------------AHL 993

Query: 924  ANTATTYGYDPVTLMQETKVTLCNIRK 950
             NT T +  D  T   E K  L N+ K
Sbjct: 994  TNTLTPFVGDGNTQTPEFKSFLVNVEK 1020