Pairwise Alignments

Query, 951 a.a., formate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 1034 a.a., formate dehydrogenase subunit alpha from Sinorhizobium meliloti 1021

 Score =  229 bits (585), Expect = 5e-64
 Identities = 184/670 (27%), Positives = 287/670 (42%), Gaps = 141/670 (21%)

Query: 19  ISRRAFMKNTSLAAGGAAVGASLFTPGMIRKAQASEVDRSAKTEVKRTICSHCSVGCGIY 78
           +SRR+F+K     A   ++GA  F              +   T   R  C +CSV CG+ 
Sbjct: 10  LSRRSFLKLAGAGAAATSLGAMGFGEAEAAVVAHVRPHKLTTTTETRNTCPYCSVACGVI 69

Query: 79  AEVQNGVWTGQ-------EPAFDHPFNAGGHCAKGAALREHGHGERRLKYPMKLEGG--K 129
              +  +  G+       E   DHP N G  C KGAAL++      RL+YPM  + G  K
Sbjct: 70  IYSKGDLRKGEAADIIHIEGDADHPTNRGTLCPKGAALKDFVKSPTRLQYPMHRKPGSDK 129

Query: 130 WKKISWEQAINEIG-------DKALKIREESGPD-----SVYFLGSAKHSNEQAYLFRKM 177
           +++ISWE A + I        D        +G       +V  L ++  +NE A+   K 
Sbjct: 130 FERISWEDAFDRIARLMKDDRDANFIAANAAGVPVNRWTTVGMLAASATTNETAWATFKF 189

Query: 178 ASLWGTNNVDHQARICHSTTVAGVANTWGYGAMTNSFNDMHNCKSMLFIGSNPAEAHPVA 237
           A   G    D+QAR+ H  TV+ +  T+G GAMTNS+ D+ N   ++ +G N AEAHP  
Sbjct: 190 AKALGIVGFDNQARVUHGPTVSSLGPTFGRGAMTNSWTDIKNTDLVVVMGGNAAEAHPCG 249

Query: 238 MQHILIAKEKNSCKIVVADPRRTRTAAKADYFVSLRPGSDVAFIWGVLWHVFKNN---WE 294
            + +  AK     K++V DPR TRTA+ +DY+  +R G+D+AF+ GV+ +   N+   W+
Sbjct: 250 FKWVTEAKATRGAKLIVVDPRYTRTASVSDYYAPIRQGTDIAFLNGVMKYCIDNDKVQWD 309

Query: 295 ------DKEYIRQRVFGMDE---------------------------------------- 308
                 +  Y+ +  FG  +                                        
Sbjct: 310 YMKAFTNASYLVKDGFGYQDGLFTGYDAEKRDYDKSTWDYVLGDDGFVVTDPALQHPRCV 369

Query: 309 ---IRAEVAKWTPAEVERVTGVSEEEVYNTAKTLAE----NRPGCVVWCMGGTQHTTGNN 361
              ++A +A +TP  VER+ G  +++    A+ ++E     +    ++ +G TQH++G+ 
Sbjct: 370 WNLLKAHLAPYTPEMVERICGTPKDKFLKVAEMISECSSPTKTMTSMYALGWTQHSSGSQ 429

Query: 362 NTRAYCILELALGNIGKSGGGANIFRGHDNVQGATDLGVLSDTLPGYY------------ 409
           N RA  +L+L LGNIG  GGG N  RGH N+QG TDLG++S  L GY             
Sbjct: 430 NIRAMAMLQLILGNIGVRGGGMNALRGHSNIQGLTDLGLMSHLLTGYLTMPTEKDVDFTT 489

Query: 410 --------GLTEGSWKHW-----------ASVWG----VDFEWIKNRFDQGTYNGALPME 446
                    L  G   +W            ++WG    +D +W         +N    ++
Sbjct: 490 YMSTRQFKPLRPGQTSYWQNYRKFMVSFQKAMWGDAARIDNDW--------AFNYLSKLD 541

Query: 447 TPGIPVSRWIDGVLENKDNLQQRENIRAMFYWGHAVNSQTRGVEMKKAMQKLDMMVIVDP 506
            P   V R  + +   K N    +    +  + +   +        KA+  L  +V +DP
Sbjct: 542 VPAYDVLRVFELMYAGKVNGYICQGFNPLLAFPNRDKN-------TKALSNLKWLVTMDP 594

Query: 507 YPTVAA-------------VMNDRTDGVYLLPATTQFETYGSVTASNRSIQWRDQVIEPL 553
             T  A               + +T+ V+ LP T   E  GS+T S R +QW      P 
Sbjct: 595 LDTETARFWENHGDFNPVDTASIQTE-VFQLPTTCFAEEEGSLTNSGRWLQWHWAGGTPP 653

Query: 554 FESKPDHEIM 563
            E+K D  I+
Sbjct: 654 GEAKHDTYIV 663



 Score = 49.3 bits (116), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 24/187 (12%)

Query: 770  PLHREPLYTPRRDLLADYPTWDDQAFIFRVPTLYKSIQAQDKSVEYPIILTSGRLVEYEG 829
            P H EP  +P  ++       +  + +F+       +     S E+P   TS RL E+  
Sbjct: 859  PAHMEPFESPVANVFNPKMRGNPVSRVFQTDVAQMGL-----SDEFPYAATSYRLTEHFH 913

Query: 830  GGEETRSNPWLAELQQEMFVEVNPKDANDLGFMDGDMVWVEGAEKGRIKVKAMVTRRVKP 889
                T+ N   + LQ E FVE++ + A +    +G  V V  +++G +K KA+VT+R++P
Sbjct: 914  YW--TKHNRVNSALQPEFFVEISEELAEEKNIENGGWVRV-WSKRGSVKAKAVVTKRIRP 970

Query: 890  GM--------AFLPFHFGGKFQGEDLRPKYPEGTQPYVVGEAANTATTY-----GYDPVT 936
             M          +P H+G  F G   +   P    P+ VG+A      Y       +P T
Sbjct: 971  LMCDGKPVHVVGIPLHWG--FTGSAKKGLGPNSLAPF-VGDANIETPEYKAFLVNIEPST 1027

Query: 937  LMQETKV 943
              +E  V
Sbjct: 1028 APEEATV 1034