Pairwise Alignments
Query, 879 a.a., MCE family protein from Vibrio cholerae E7946 ATCC 55056
Subject, 539 a.a., mammalian cell entry protein from Burkholderia phytofirmans PsJN
Score = 181 bits (459), Expect = 1e-49
Identities = 101/315 (32%), Positives = 169/315 (53%), Gaps = 12/315 (3%)
Query: 13 PEIRKRRGISP--LWILPIVTMILAGWLVFKAVHDAGVRIQIHFENAQGLIAGRTTIRYQ 70
P+I RRG P +W++P++ ++ LV +AV + G I I F+NA+GL G+T ++Y+
Sbjct: 16 PDIVPRRGWLPSLVWVVPLIAALIGLALVVRAVTERGPAITIVFDNAEGLEPGKTQVKYK 75
Query: 71 GLEVGMVRDIKLSEGLDSIYVEADIYPEATKLLSNQTRFWMVKPTASLSGVSGLDALVSG 130
+E+G V+ I LS+ + + + +A TRFW+V+P +GVSG+ L+SG
Sbjct: 76 DVEIGSVKSITLSKDRTHVQIAVQLTRQAENFAVKDTRFWVVRPRVGAAGVSGIGTLLSG 135
Query: 131 NYIAIQPGSTHQEDYPTQYQALDSAPSDLLAQRGLTISLKARDLGGISVGSQIVYKKIPI 190
YI + G + T++ L++ P AQ+G +L LG I +GS I Y+++ +
Sbjct: 136 AYIGVDVG--RSTETRTEFVGLETPPPITAAQKGHRFTLHGDSLGSIDIGSPIFYRRVQV 193
Query: 191 GEVFSYQLDDDAQSVIIQASIKEEYQHIINTESRFWNVSGIGASIGFEGVDVRLESLSAL 250
G+V+ LD D V +Q + Y + + SR+W+ SG+ + G V +SL+A+
Sbjct: 194 GQVYGISLDKDGTGVTMQVFVAAPYDQYVGSNSRWWHASGVDVRLDSTGFVVNTQSLAAI 253
Query: 251 IGGSIAVDSP---DEGKPVEQNAQFRLYRDLKTAGR---GIAVSITLPDDNNIS--ASGA 302
+ G +A +P G P + FRL D A R GI V + ++ + GA
Sbjct: 254 LVGGLAFQTPPGQPMGTPAAEKTDFRLAADEVDAMRAPDGIRVRTVMVFSQSLRGLSVGA 313
Query: 303 PIMYRGIEIGQITDL 317
+ +RGI +GQ+TD+
Sbjct: 314 TVDFRGIVLGQVTDI 328
Score = 102 bits (255), Expect = 5e-26
Identities = 73/244 (29%), Positives = 122/244 (50%), Gaps = 10/244 (4%)
Query: 638 GEKITLTALGTLGVKVG-TPVQYQGVQIGEVFEIIPDFESDFVKLAARIEPQYAPKIAKQ 696
G IT+ G++ G T V+Y+ V+IG V I + V++A ++ Q A A +
Sbjct: 52 GPAITIVFDNAEGLEPGKTQVKYKDVEIGSVKSITLSKDRTHVQIAVQLTRQ-AENFAVK 110
Query: 697 NSQFWLSQAKIGLSGIENVQNLL-GQSIEVQPGNG-ESRFEF---ELHKEARHGGAGNTY 751
+++FW+ + ++G +G+ + LL G I V G E+R EF E G+ +
Sbjct: 111 DTRFWVVRPRVGAAGVSGIGTLLSGAYIGVDVGRSTETRTEFVGLETPPPITAAQKGHRF 170
Query: 752 TLQSEKRGSVSVGTPILYRDIEVGKVIDVRLGEFADRVITTIRIAPQYTYLLRQNSVFWN 811
TL + GS+ +G+PI YR ++VG+V + L + V + +A Y + NS +W+
Sbjct: 171 TLHGDSLGSIDIGSPIFYRRVQVGQVYGISLDKDGTGVTMQVFVAAPYDQYVGSNSRWWH 230
Query: 812 VSGLDMSIGITGANVKAGTFDSMLRGGITFATPEQKQLTPAAPEGHTFYLYPQAQEEWTK 871
SG+D+ + TG V + ++L GG+ F TP + + A E F L A +E
Sbjct: 231 ASGVDVRLDSTGFVVNTQSLAAILVGGLAFQTPPGQPMGTPAAEKTDFRL---AADEVDA 287
Query: 872 WRTP 875
R P
Sbjct: 288 MRAP 291
Score = 87.0 bits (214), Expect = 3e-21
Identities = 77/292 (26%), Positives = 130/292 (44%), Gaps = 28/292 (9%)
Query: 400 SFNLVADNSFGLEAG-TPILYRGVAVGSVTAVNLKLD--YVEFNVLIDEQYGALIRSQNR 456
+ +V DN+ GLE G T + Y+ V +GSV ++ L D +V+ V + Q R
Sbjct: 54 AITIVFDNAEGLEPGKTQVKYKDVEIGSVKSITLSKDRTHVQIAVQLTRQAENFAVKDTR 113
Query: 457 FYVTGSAAAELTESGLSVSIPPAKQLLLGSISFASEGSSTPLEQYRLYSSQSLAELAKYN 516
F+V SG+ LL G+ G ST E +
Sbjct: 114 FWVVRPRVGAAGVSGIGT-------LLSGAYIGVDVGRST--ETRTEFVGLETPPPITAA 164
Query: 517 QSGSRSLTLFAHELPSINAGSPLLYRNLKVGSISGFTLTPKG--VQIEATIEKQYQHLLT 574
Q G R TL L SI+ GSP+ YR ++VG + G +L G V ++ + Y +
Sbjct: 165 QKGHR-FTLHGDSLGSIDIGSPIFYRRVQVGQVYGISLDKDGTGVTMQVFVAAPYDQYVG 223
Query: 575 PDTVFWNRSGVEIKASMDGVDVKAAPLQTLIRGGIAFDNLPGIENKVGSM------WKLY 628
++ +W+ SGV+++ G V L ++ GG+AF PG +G+ ++L
Sbjct: 224 SNSRWWHASGVDVRLDSTGFVVNTQSLAAILVGGLAFQTPPG--QPMGTPAAEKTDFRLA 281
Query: 629 SDYDHARRYGEKITLTAL-----GTLGVKVGTPVQYQGVQIGEVFEIIPDFE 675
+D A R + I + + G+ VG V ++G+ +G+V +I +++
Sbjct: 282 ADEVDAMRAPDGIRVRTVMVFSQSLRGLSVGATVDFRGIVLGQVTDIGVEYD 333
Score = 57.4 bits (137), Expect = 2e-12
Identities = 62/299 (20%), Positives = 119/299 (39%), Gaps = 36/299 (12%)
Query: 160 LAQRGLTISLKARDLGGISVG-SQIVYKKIPIGEVFSYQLDDDAQSVIIQASIKEEYQHI 218
+ +RG I++ + G+ G +Q+ YK + IG V S L D V I + + ++
Sbjct: 48 VTERGPAITIVFDNAEGLEPGKTQVKYKDVEIGSVKSITLSKDRTHVQIAVQLTRQAENF 107
Query: 219 INTESRFWNVSGIGASIGFEGVDVRLESLSALIGGSIAVDSPDEGKPVEQNAQF---RLY 275
++RFW V + G G+ L G I VD G+ E +F
Sbjct: 108 AVKDTRFWVVRPRVGAAGVSGIGTLLS------GAYIGVDV---GRSTETRTEFVGLETP 158
Query: 276 RDLKTAGRGIAVSITLPDDNNISAS-GAPIMYRGIEIGQITDLQLTENRKSIVASAAIQP 334
+ A +G TL D+ S G+PI YR +++GQ+ + L ++ + +
Sbjct: 159 PPITAAQKGHR--FTLHGDSLGSIDIGSPIFYRRVQVGQVYGISLDKDGTGVTMQVFVAA 216
Query: 335 AFSDMLNQGSQF-------VLEEAQVSLTGVENLTNLVKGNYLTLIPGAGERTRNFQAVR 387
+ + S++ V ++ + ++L ++ G P + A
Sbjct: 217 PYDQYVGSNSRWWHASGVDVRLDSTGFVVNTQSLAAILVGGLAFQTPPG--QPMGTPAAE 274
Query: 388 KNEFKYARSNSISFN-----------LVADNSFGLEAGTPILYRGVAVGSVTAVNLKLD 435
K +F+ A + + + + GL G + +RG+ +G VT + ++ D
Sbjct: 275 KTDFRLAADEVDAMRAPDGIRVRTVMVFSQSLRGLSVGATVDFRGIVLGQVTDIGVEYD 333
Score = 52.4 bits (124), Expect = 7e-11
Identities = 61/263 (23%), Positives = 113/263 (42%), Gaps = 31/263 (11%)
Query: 541 YRNLKVGSISGFTLTPKG--VQIEATIEKQYQHLLTPDTVFWNRSGVEIKASMDGVDVKA 598
Y+++++GS+ TL+ VQI + +Q ++ DT FW V + GV
Sbjct: 74 YKDVEIGSVKSITLSKDRTHVQIAVQLTRQAENFAVKDTRFWV---VRPRVGAAGV---- 126
Query: 599 APLQTLIRGG-IAFDNLPGIENKVGSMWKLYSDYDHARRYGEKITLTALGTLGVKVGTPV 657
+ + TL+ G I D E + + A + G + TL + +G+P+
Sbjct: 127 SGIGTLLSGAYIGVDVGRSTETRTEFVGLETPPPITAAQKGHRFTLHGDSLGSIDIGSPI 186
Query: 658 QYQGVQIGEVFEIIPDFESDFVKLAARIEPQYAPKIAKQNSQFWLS---QAKIGLSG-IE 713
Y+ VQ+G+V+ I D + V + + Y + NS++W + ++ +G +
Sbjct: 187 FYRRVQVGQVYGISLDKDGTGVTMQVFVAAPYDQYVG-SNSRWWHASGVDVRLDSTGFVV 245
Query: 714 NVQNLL-----GQSIEVQPGN-----GESRFEFELHKE------ARHGGAGNTYTLQSEK 757
N Q+L G + + PG + +F L + A G T + S+
Sbjct: 246 NTQSLAAILVGGLAFQTPPGQPMGTPAAEKTDFRLAADEVDAMRAPDGIRVRTVMVFSQS 305
Query: 758 RGSVSVGTPILYRDIEVGKVIDV 780
+SVG + +R I +G+V D+
Sbjct: 306 LRGLSVGATVDFRGIVLGQVTDI 328
Score = 34.3 bits (77), Expect = 2e-05
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 30/179 (16%)
Query: 47 GVRIQIHFENAQGLIAGRTTIRYQGLEVGMVRDIKLSEGLDSIYVEADIYPEATKLLSNQ 106
G R +H ++ + G + I Y+ ++VG V I L + + ++ + + + +
Sbjct: 167 GHRFTLHGDSLGSIDIG-SPIFYRRVQVGQVYGISLDKDGTGVTMQVFVAAPYDQYVGSN 225
Query: 107 TRFW-------------MVKPTASLSGVSGLDALVSGNYIAIQPG------STHQEDYPT 147
+R+W V T SL+ + LV G PG + + D+
Sbjct: 226 SRWWHASGVDVRLDSTGFVVNTQSLAAI-----LVGGLAFQTPPGQPMGTPAAEKTDFRL 280
Query: 148 QYQALDS--APSDLLAQRGLTISLKARDLGGISVGSQIVYKKIPIGEVFSYQLDDDAQS 204
+D+ AP + R T+ + ++ L G+SVG+ + ++ I +G+V ++ D Q+
Sbjct: 281 AADEVDAMRAPDGI---RVRTVMVFSQSLRGLSVGATVDFRGIVLGQVTDIGVEYDPQA 336