Pairwise Alignments
Query, 879 a.a., MCE family protein from Vibrio cholerae E7946 ATCC 55056
Subject, 552 a.a., mammalian cell entry protein from Burkholderia phytofirmans PsJN
Score = 172 bits (435), Expect = 6e-47
Identities = 100/323 (30%), Positives = 167/323 (51%), Gaps = 12/323 (3%)
Query: 13 PEIRKRRGISP--LWILPIVTMILAGWLVFKAVHDAGVRIQIHFENAQGLIAGRTTIRYQ 70
PEI R P +W++P++ ++ LV K+V G I I F +A+GL G+T ++Y+
Sbjct: 30 PEIEPRSRWLPSLVWMIPLIAALIGIALVIKSVTARGPTITISFVSAEGLEPGKTKVKYK 89
Query: 71 GLEVGMVRDIKLSEGLDSIYVEADIYPEATKLLSNQTRFWMVKPTASLSGVSGLDALVSG 130
++VG V+ I LS+ L + V+ + E +RFW+V+P SGVSGL L+SG
Sbjct: 90 DVDVGSVKTITLSKDLSHVLVQVQLTKEGEDFAVKDSRFWVVRPRVGASGVSGLTTLLSG 149
Query: 131 NYIAIQPGSTHQEDYPTQYQALDSAPSDLLAQRGLTISLKARDLGGISVGSQIVYKKIPI 190
YI G H D + L++ P Q+G L LG I +GS I Y+++ +
Sbjct: 150 AYIGADAG--HSPDTEKNFVGLETPPPITGDQKGHQFVLHGDSLGSIDIGSPIFYRRVQV 207
Query: 191 GEVFSYQLDDDAQSVIIQASIKEEYQHIINTESRFWNVSGIGASIGFEGVDVRLESLSAL 250
G+V + LD D V +Q + + + T SR+W+ SG+ + G + +SL+ +
Sbjct: 208 GQVVGFSLDKDGTGVTMQVFVSAPFDQYVGTNSRWWHASGVDLRLDSSGFKLNTQSLATV 267
Query: 251 IGGSIAVDSP---DEGKPVEQNAQFRLYRDLKTAGR---GIAVSITLPDDNNIS--ASGA 302
I G ++ SP G N FRL D A R G+ + + + + ++ + GA
Sbjct: 268 IVGGLSFQSPPGQGVGAQAPNNMTFRLGSDEADAMREPDGVPLRVVMNFNQSLRGLSIGA 327
Query: 303 PIMYRGIEIGQITDLQLTENRKS 325
P+ +RGI +GQ+T++ + + K+
Sbjct: 328 PVDFRGIVLGQVTNIGIDYDPKT 350
Score = 89.0 bits (219), Expect = 7e-22
Identities = 55/230 (23%), Positives = 111/230 (48%), Gaps = 7/230 (3%)
Query: 638 GEKITLTALGTLGVKVG-TPVQYQGVQIGEVFEIIPDFESDFVKLAARIEPQYAPKIAKQ 696
G IT++ + G++ G T V+Y+ V +G V I + V + ++ + A +
Sbjct: 66 GPTITISFVSAEGLEPGKTKVKYKDVDVGSVKTITLSKDLSHVLVQVQLTKE-GEDFAVK 124
Query: 697 NSQFWLSQAKIGLSGIENVQNLL-----GQSIEVQPGNGESRFEFELHKEARHGGAGNTY 751
+S+FW+ + ++G SG+ + LL G P ++ E G+ +
Sbjct: 125 DSRFWVVRPRVGASGVSGLTTLLSGAYIGADAGHSPDTEKNFVGLETPPPITGDQKGHQF 184
Query: 752 TLQSEKRGSVSVGTPILYRDIEVGKVIDVRLGEFADRVITTIRIAPQYTYLLRQNSVFWN 811
L + GS+ +G+PI YR ++VG+V+ L + V + ++ + + NS +W+
Sbjct: 185 VLHGDSLGSIDIGSPIFYRRVQVGQVVGFSLDKDGTGVTMQVFVSAPFDQYVGTNSRWWH 244
Query: 812 VSGLDMSIGITGANVKAGTFDSMLRGGITFATPEQKQLTPAAPEGHTFYL 861
SG+D+ + +G + + +++ GG++F +P + + AP TF L
Sbjct: 245 ASGVDLRLDSSGFKLNTQSLATVIVGGLSFQSPPGQGVGAQAPNNMTFRL 294
Score = 88.2 bits (217), Expect = 1e-21
Identities = 80/298 (26%), Positives = 137/298 (45%), Gaps = 30/298 (10%)
Query: 394 ARSNSISFNLVADNSFGLEAG-TPILYRGVAVGSVTAVNLKLD--YVEFNVLIDEQYGAL 450
AR +I+ + V+ GLE G T + Y+ V VGSV + L D +V V + ++
Sbjct: 64 ARGPTITISFVSAE--GLEPGKTKVKYKDVDVGSVKTITLSKDLSHVLVQVQLTKEGEDF 121
Query: 451 IRSQNRFYVTGSAAAELTESGLSVSIPPAKQLLLGSISFASEGSSTPLEQYRLYSSQSLA 510
+RF+V SGL+ LL G+ A G S E+ +
Sbjct: 122 AVKDSRFWVVRPRVGASGVSGLTT-------LLSGAYIGADAGHSPDTEKN--FVGLETP 172
Query: 511 ELAKYNQSGSRSLTLFAHELPSINAGSPLLYRNLKVGSISGFTLTPKG--VQIEATIEKQ 568
+Q G + L L SI+ GSP+ YR ++VG + GF+L G V ++ +
Sbjct: 173 PPITGDQKGHQ-FVLHGDSLGSIDIGSPIFYRRVQVGQVVGFSLDKDGTGVTMQVFVSAP 231
Query: 569 YQHLLTPDTVFWNRSGVEIKASMDGVDVKAAPLQTLIRGGIAFDNLPGIENKVGSM---- 624
+ + ++ +W+ SGV+++ G + L T+I GG++F + PG VG+
Sbjct: 232 FDQYVGTNSRWWHASGVDLRLDSSGFKLNTQSLATVIVGGLSFQSPPG--QGVGAQAPNN 289
Query: 625 --WKLYSDYDHARRYGEKITLTAL-----GTLGVKVGTPVQYQGVQIGEVFEIIPDFE 675
++L SD A R + + L + G+ +G PV ++G+ +G+V I D++
Sbjct: 290 MTFRLGSDEADAMREPDGVPLRVVMNFNQSLRGLSIGAPVDFRGIVLGQVTNIGIDYD 347
Score = 74.7 bits (182), Expect = 1e-17
Identities = 58/285 (20%), Positives = 116/285 (40%), Gaps = 10/285 (3%)
Query: 283 RGIAVSITLPDDNNISASGAPIMYRGIEIGQITDLQLTENRKSIVASAAIQPAFSDMLNQ 342
RG ++I+ + + Y+ +++G + + L+++ ++ + D +
Sbjct: 65 RGPTITISFVSAEGLEPGKTKVKYKDVDVGSVKTITLSKDLSHVLVQVQLTKEGEDFAVK 124
Query: 343 GSQFVLEEAQVSLTGVENLTNLVKGNYLTLIPGAGERT-RNFQAVRKNEFKYARSNSISF 401
S+F + +V +GV LT L+ G Y+ G T +NF + F
Sbjct: 125 DSRFWVVRPRVGASGVSGLTTLLSGAYIGADAGHSPDTEKNFVGLETPPPITGDQKGHQF 184
Query: 402 NLVADNSFGLEAGTPILYRGVAVGSVTAVNLKLD--YVEFNVLIDEQYGALIRSQNRFYV 459
L D+ ++ G+PI YR V VG V +L D V V + + + + +R++
Sbjct: 185 VLHGDSLGSIDIGSPIFYRRVQVGQVVGFSLDKDGTGVTMQVFVSAPFDQYVGTNSRWWH 244
Query: 460 TGSAAAELTESGLSVSIPPAKQLLLGSISFASE-----GSSTPLEQYRLYSSQSLAELAK 514
L SG ++ +++G +SF S G+ P S + +
Sbjct: 245 ASGVDLRLDSSGFKLNTQSLATVIVGGLSFQSPPGQGVGAQAPNNMTFRLGSDEADAMRE 304
Query: 515 YNQSGSRSLTLFAHELPSINAGSPLLYRNLKVGSIS--GFTLTPK 557
+ R + F L ++ G+P+ +R + +G ++ G PK
Sbjct: 305 PDGVPLRVVMNFNQSLRGLSIGAPVDFRGIVLGQVTNIGIDYDPK 349
Score = 37.7 bits (86), Expect = 2e-06
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 37/266 (13%)
Query: 541 YRNLKVGSISGFTLTP--KGVQIEATIEKQYQHLLTPDTVFWNRSGVEIKASMDGVDVKA 598
Y+++ VGS+ TL+ V ++ + K+ + D+ FW V + GV
Sbjct: 88 YKDVDVGSVKTITLSKDLSHVLVQVQLTKEGEDFAVKDSRFWV---VRPRVGASGV---- 140
Query: 599 APLQTLIRG---GIAFDNLPGIE-NKVGSMWKLYSDYDHARRYGEKITLTALGTLGVKVG 654
+ L TL+ G G + P E N VG D G + L + +G
Sbjct: 141 SGLTTLLSGAYIGADAGHSPDTEKNFVGLETPPPITGDQK---GHQFVLHGDSLGSIDIG 197
Query: 655 TPVQYQGVQIGEVFEIIPDFESDFVKLAARIEPQYAPKIAKQNSQFWLSQA---KIGLSG 711
+P+ Y+ VQ+G+V D + V + + + + NS++W + ++ SG
Sbjct: 198 SPIFYRRVQVGQVVGFSLDKDGTGVTMQVFVSAPFDQYVGT-NSRWWHASGVDLRLDSSG 256
Query: 712 IE-NVQNLL-----GQSIEVQPGNG-----ESRFEFELHKEARHG-----GAGNTYTLQ- 754
+ N Q+L G S + PG G + F L + G +
Sbjct: 257 FKLNTQSLATVIVGGLSFQSPPGQGVGAQAPNNMTFRLGSDEADAMREPDGVPLRVVMNF 316
Query: 755 SEKRGSVSVGTPILYRDIEVGKVIDV 780
++ +S+G P+ +R I +G+V ++
Sbjct: 317 NQSLRGLSIGAPVDFRGIVLGQVTNI 342