Pairwise Alignments

Query, 336 a.a., dihydroorotate dehydrogenase (quinone) from Vibrio cholerae E7946 ATCC 55056

Subject, 357 a.a., Probable dihydroorotate dehydrogenase PyrD from Mycobacterium tuberculosis H37Rv

 Score =  230 bits (586), Expect = 5e-65
 Identities = 136/337 (40%), Positives = 188/337 (55%), Gaps = 15/337 (4%)

Query: 2   LYRLARAGFFQLDAEKAHDLAISNFKRFTGT-PFDLFYRQQL-PHRPVQC---MGLTFKN 56
           +Y L R   F +  E AH L  +  +      P     R+ L P  PV      G+ F  
Sbjct: 1   MYPLVRRLLFLIPPEHAHKLVFAVLRGVAAVAPVRRLLRRLLGPTDPVLASTVFGVRFPA 60

Query: 57  PVGLAAGLDKNGECIEAFGAMGFGFVEVGTVTPRPQAGNDKPRLFRLVHAEGIINRMGFN 116
           P+GLAAG DK+G  + ++GAMGFG+ E+GTVT  PQ GN  PRLFRL     ++NRMGFN
Sbjct: 61  PLGLAAGFDKDGTALSSWGAMGFGYAEIGTVTAHPQPGNPAPRLFRLADDRALLNRMGFN 120

Query: 117 NLGVDHLVENVKRAKYDGIIGINIGKNKDTPIEKGAEDYLICMDKVYPYAGYIAVNISSP 176
           N G   L   + R + +  IG+NIGK K TP      DY      V P A Y+ VN+SSP
Sbjct: 121 NHGARALAIRLARHRPEIPIGVNIGKTKKTPAGDAVNDYRASARMVGPLASYLVVNVSSP 180

Query: 177 NTPGLRSLQYGEALDELLAALKTRQAELAAKHDKYVPLALKIAPDLSDDEIQQICQSLLK 236
           NTPGLR LQ  E+L  +L+A++   +          P+ +KIAPDLSD ++  I    ++
Sbjct: 181 NTPGLRDLQAVESLRPILSAVRAETS---------TPVLVKIAPDLSDSDLDDIADLAVE 231

Query: 237 NKIDSVIATNTTLDR-SLVEGMKFANEAGGLSGRPLQNRSTEVIKCLYKELGEEIPIIGV 295
             +  ++ATNTT+ R  L          GG+SG PL  R+ +V++ LY  +G+ + +I V
Sbjct: 232 LDLAGIVATNTTVSRDGLTTPGVDRLGPGGISGPPLAQRAVQVLRRLYDRVGDRLALISV 291

Query: 296 GGIDSYISAKEKLLAGAKLVQVYSGFIYQGPGLVADI 332
           GGI++   A E++ AGA L+Q Y+GFIY G     DI
Sbjct: 292 GGIETADDAWERITAGASLLQGYTGFIYGGERWAKDI 328