Pairwise Alignments

Query, 572 a.a., hybrid sensor histidine kinase/response regulator from Vibrio cholerae E7946 ATCC 55056

Subject, 1358 a.a., multi-sensor hybrid histidine kinase (RefSeq) from Desulfovibrio vulgaris Miyazaki F

 Score =  224 bits (570), Expect = 2e-62
 Identities = 142/410 (34%), Positives = 223/410 (54%), Gaps = 32/410 (7%)

Query: 190  LVEIRTRELRL--AQKLAEQANQSKSNFLAMMSHELRTPLNAVLGLIDILRGE-LTSYQV 246
            + E +  EL L  A+++AE A ++KS FLA MSHELRTP+N VLG++ +L    L   Q 
Sbjct: 931  ITERKNAELELINAREVAETATKAKSAFLANMSHELRTPMNGVLGMLQLLDATPLDPEQR 990

Query: 247  ELLEQMENSAELLLIIINDILDLSRIESGHFSLHCHWLDLEKKLDQSLVYHRQIAQDKGV 306
              ++    +   L  ++ D+LDL+R+ESG  ++     D      + L   R  A  KG+
Sbjct: 991  GYVQVAHAAGSNLTRLLGDLLDLARVESGRLTIREEPFDFNGLTQEVLAVLRPEADRKGI 1050

Query: 307  HFYVQSNKNPTLEYYTDSARLTQILFNIVGNAIKFTKQGQVDVVLDYTKDG--------- 357
                 ++  P      D  R+ Q+L NIVGNA+KFT +G V ++  +             
Sbjct: 1051 VLEAATDGMPGA-LLGDPQRIRQMLLNIVGNAVKFTDRGHVRLLARFEPSAGPSATAEPG 1109

Query: 358  ----------VVFRVKDTGIGIEKNRVEQLFTPFIQADNSITRNYGGTGLGLAITKHLVE 407
                      +   V+DTGIGI  + +  +F PF Q +++++R +GG GLGL+I + +V+
Sbjct: 1110 GQGEPGGQGTLYLAVEDTGIGIPSDMLGNIFEPFTQVEDAVSRRHGGAGLGLSIVRRIVD 1169

Query: 408  LMGGTIQVESEFGIGTTFTLYIPL--QSRLKNIKPSTSSSQQIVNVKNHHILVVEDTKTN 465
            LM G + + SE G GTT TL +P+    RL   +P T +      V+   +L+VED   N
Sbjct: 1170 LMEGEVSMTSEEGRGTTVTLRLPVAAMDRLPAQEP-TRNGLADPPVRQGRLLLVEDDHVN 1228

Query: 466  QMVIQLLLNKLGYDVTIAENGLQAVELLEKNHVFDLVLMDISMPIMDGIAATKILRDK-- 523
            ++ +  +L KLGYD     +G  A++ L +   FD VLMD+ MP+MDG+ AT  +R+   
Sbjct: 1229 RLTVLWMLEKLGYDALAVGDGAAALQALRQGR-FDAVLMDVQMPVMDGLQATAAIRNATD 1287

Query: 524  ---HIEIPIIALTAHTAGSDKQNCIDAGMNDIVLKPIRSKDIMEVVKRFL 570
                 E+P+IALTA+    D++  + AGM+D V KP+  + +  V+ RF+
Sbjct: 1288 LPGGAEVPVIALTAYAMEGDRERLLAAGMDDYVEKPVDVQALRRVLSRFV 1337



 Score =  121 bits (303), Expect = 2e-31
 Identities = 119/467 (25%), Positives = 208/467 (44%), Gaps = 40/467 (8%)

Query: 131 PVYSALITGIQAQISDSVLILLGQNKGQFSLEAKETLSRFRPLLERAISDIEHKEELQKL 190
           PV S ++      ++ ++ + +G          ++ + R     ER  ++    +E    
Sbjct: 114 PVLSFMVVKPVDVVAVAMFLGIGLMISLAHQRVRDAVRRVVETQERQQAERVEADEATSR 173

Query: 191 VEIRTRELRLAQKLAEQANQSKSNFLAMMSHELRTPLNAVLGLIDILRGELTS---YQVE 247
           +     EL      AE+ +  K+ F A +SHELRTPL  +LG ++ L  E +    ++  
Sbjct: 174 LRATNAELAARCARAEELDVLKTRFFANISHELRTPLTLLLGPLERLLAETSEDDEHRHS 233

Query: 248 LLEQMENSAELLLIIINDILDLSRIESGHFSLHCHWLDLEKKLDQSLVYHRQIAQDKGVH 307
           L   + N A LL   ++D+LDLSR+++G         DL      +  Y   +A  +G+H
Sbjct: 234 LFTMLRN-ARLLHQHVDDMLDLSRVDAGAMQPRHAEADLSALTRTTCAYFDTLAAQRGMH 292

Query: 308 FYVQSNKNPTLEYYTDSARLTQILFNIVGNAIKFTKQG-QVDVVLDYTKDGVVFRVKDTG 366
           + VQ+     L+   D+ +  +IL N++ N+ KFT  G  V V L+   D  +  V D G
Sbjct: 293 YGVQAPLR--LDAQVDTDKYRRILLNLLSNSFKFTPDGGSVSVTLERQGDEALLSVSDDG 350

Query: 367 IGIEKNRVEQLFTPFIQADNSITRNYGGTGLGLAITKHLVELMGGTIQVESEFGIGTTFT 426
            G+  +    +F  + Q+       +GG+GLGLAI K   EL GGT  V      G  F 
Sbjct: 351 PGVPAHLRGAVFERYRQSGEGARGLHGGSGLGLAIVKEFAELHGGTTSVGQGAEGGALFQ 410

Query: 427 LYIPLQ-------SRLKNIKPSTSSSQQIVNVKNHH--------------ILVVEDTKTN 465
           + +PL        +  +++  S S +     + + H              +LVVED +  
Sbjct: 411 VRLPLAAPPGVEVAPAESVAGSGSFAGDPGWLASGHVPQYAPAAGRDGGLVLVVEDNRDM 470

Query: 466 QMVIQLLLNKLGYDVTIA---ENGL-QAVELLEKNHVFDLVLMDISMPIMDGIAATKILR 521
              I  +L +  + V +A   E GL +A++L       DL++ D+ MP +DG    + LR
Sbjct: 471 IAYIVDIL-RPHHQVAVAFDGEEGLRKALDLRP-----DLIVCDVMMPRVDGQRMVEQLR 524

Query: 522 --DKHIEIPIIALTAHTAGSDKQNCIDAGMNDIVLKPIRSKDIMEVV 566
                 ++P++ LTA      + + +   +   + KP  +  ++  V
Sbjct: 525 RYPGMADVPVLMLTAKADDELRVHLLHGAVQGYIQKPFTAAGLLASV 571