Pairwise Alignments

Query, 787 a.a., DNA polymerase II from Vibrio cholerae E7946 ATCC 55056

Subject, 784 a.a., DNA-directed DNA polymerase from Methanococcus maripaludis S2

 Score =  137 bits (344), Expect = 3e-36
 Identities = 154/615 (25%), Positives = 272/615 (44%), Gaps = 68/615 (11%)

Query: 196 IQWVEDEYQLLKALIAWFEQFDPDVIIGWSVVDFDFRLLHKRAEFHKLKLTIGRAQQPSF 255
           +++V+DE +L+K +I   +++D  +I  ++  +FDF  L KRAE   L+L +G+  +   
Sbjct: 193 LEYVKDEKELIKRIIEILKEYD--IIYTYNGDNFDFPYLKKRAESFGLELKLGKNDEKIK 250

Query: 256 FRTASQTQQGFISIPGRVVLDGIDTLKTATYHFRSWSLESVSQELLGEGKAIHNVHDRMD 315
                   + +I  PGRV +D +  +     +   + LE+V++ L      +  V    +
Sbjct: 251 ITKGGMNSKSYI--PGRVHID-LYPIARRLLNLTKYRLENVTEALFD----VKKVDVGHE 303

Query: 316 EINQMFRHDKPSLARYNLQDCVLVNKIFAATHLLDFAIQRSRLTGVELDRIG--GSVAAF 373
            I +M+ +   +L  Y+ QD     +I      L   I  SR+    L  I    S    
Sbjct: 304 NIPKMWDNLDETLVEYSHQDAYYTQRI--GEQFLPLEIMFSRVVNQSLYDINRMSSSQMV 361

Query: 374 TNLYLPQLHRAGYVAPN------LQPENWVASPGGYVMDSIPGLYDSVLVLDFKSLYPSI 427
             L L   ++ G +APN       Q     +  GGYV + + G+++ ++ +DF SLYPSI
Sbjct: 362 EYLLLKNSYKMGVIAPNRPSGKEYQKRIRSSYEGGYVKEPLKGIHEDIVSMDFLSLYPSI 421

Query: 428 IRSFLIDPLGL-------------IEGLKLPIGKQADHAVPGFRGGQFHRTKHFLPEMIE 474
           I S  + P  +              E L     K++   +P       +R K     + E
Sbjct: 422 IMSHNLSPETIDCTCCSDEENGENEEILGHKFCKKSIGIIPKTLMDLINRRKKVKKVLRE 481

Query: 475 KLWAARDEAKRNQEKAFSQAIKIIMNSFYGVLGSSGCRFFDARLASSITMRGHEIMIQTK 534
           K      + +        ++IK++ NS YG L     R++    A   T  G + + +T 
Sbjct: 482 KAEKGEFDEEYQILDYEQRSIKVLANSHYGYLAFPMARWYSRDCAEITTHLGRQYIQKTI 541

Query: 535 RLIEARGYQVIYGDTDSTFVALGGQYSQQEADNIGHALVREINQWWTEHLKQ-EYALTSI 593
              E  G++VIY DTD       G YS+  AD+       E+ +   E LK     L   
Sbjct: 542 EEAENFGFKVIYADTD-------GFYSKW-ADDKEKLSKYELLEKTREFLKNINNTLPGE 593

Query: 594 LELEYETHYRRFLMPTIRGSETGSKKRYAGLKGDGDNEQLIFKGLESARTDWTPLAQRFQ 653
           +ELE+E +++R +  T        KK+YA +    +NE++  KGLE  R DW+ +++  Q
Sbjct: 594 MELEFEGYFKRGIFVT--------KKKYALI---DENEKITVKGLEVVRRDWSNVSKNTQ 642

Query: 654 -HQLYQLIFHG--QDPESYIRTIVEQTLAGQLDDQ-LVYQKRLRRRLHEYQKNVPPQVRA 709
            + L  L+  G  ++ +  I+  +++   G+++++ L+   +L +R+ +Y K   P V  
Sbjct: 643 KNVLNALLKEGSVENAKKVIQDTIKELKDGKVNNEDLLIHTQLTKRIEDY-KTTAPHVEV 701

Query: 710 ARMADDINAKLGRPLQYQYRGTIEYVITVNGPEPKEYSK-----SPIDYQHYIDKQLKPV 764
           A+       K G   +      I Y+IT       E ++        D  +YI+ Q+ P 
Sbjct: 702 AKKI----LKSGN--RVNTGDVISYIITSGNKSISERAEILENAKNYDTNYYIENQILPP 755

Query: 765 ADAILPFIGKQFDEL 779
              ++  +G   DEL
Sbjct: 756 VIRLMEALGITKDEL 770