Pairwise Alignments

Query, 562 a.a., NAD-dependent malic enzyme from Vibrio cholerae E7946 ATCC 55056

Subject, 548 a.a., Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me) from Mycobacterium tuberculosis H37Rv

 Score =  434 bits (1116), Expect = e-126
 Identities = 229/543 (42%), Positives = 334/543 (61%), Gaps = 8/543 (1%)

Query: 15  PALLSTPLLNKGSAFSAEERASFNLEGLLPEATETIQEQVVRAYQQYRGFESDMDKHIYL 74
           PA LS P LN+G  F+  +R    L G LP A  T+ +Q  R + Q +   +++ +++ L
Sbjct: 10  PAALSAPSLNRGVGFTHAQRRRLGLTGRLPSAVLTLDQQAERVWHQLQSLATELGRNLLL 69

Query: 75  RNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFISYANRDRIDD 134
             +   +E L+++++ +H+ E+MP++YTPTVG A + FS+ YR  RGLF+S    D I++
Sbjct: 70  EQLHYRHEVLYFKVLADHLPELMPVVYTPTVGEAIQRFSDEYRGQRGLFLSIDEPDEIEE 129

Query: 135 LLNNAA--NHNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVL 192
             N       +V +IV TD E ILG+GD G+GG+ I +GKL+LYTA GG+ P   L V L
Sbjct: 130 AFNTLGLGPEDVDLIVCTDAEAILGIGDWGVGGIQIAVGKLALYTAGGGVDPRRCLAVSL 189

Query: 193 DVGTNNPQRLADPMYMGWRHPRITGPDYDNFVEEFMQAVQRRWPDALIQFEDFAQKNAMP 252
           DVGT+N Q LADP Y+G RH R  G +YD FV  +++  QR +P A++ FEDF   NA  
Sbjct: 190 DVGTDNEQLLADPFYLGNRHARRRGREYDEFVSRYIETAQRLFPRAILHFEDFGPANARK 249

Query: 253 LLERYKNRVCCFNDDIQGTAAVTVGSLLAACKAAGSQLSQQRITFLGAGSAGCGIAEAII 312
           +L+ Y    C FNDD+QGT AV + ++ +  K  G  L  Q I   GAG+AG GIA+ I 
Sbjct: 250 ILDTYGTDYCVFNDDMQGTGAVVLAAVYSGLKVTGIPLRDQTIVVFGAGTAGMGIADQIR 309

Query: 313 AQMVSEGISDEQARSQVYMVDRWGLLEEGMPNLLDFQQRLVQKKANTQHWTTENNGYSLH 372
             MV++G + EQA SQ++ +DR GLL + M +L DFQ  +   K   Q      +   L 
Sbjct: 310 DAMVADGATLEQAVSQIWPIDRPGLLFDDMDDLRDFQ--VPYAKNRHQLGVAVGDRVGLS 367

Query: 373 DVIRNAKPTVLVGVSGAPGLFSEEIIKEMHQHCPRPIVFPLSNPTSRVEALPSDIIRWTN 432
           D I+ A PT+L+G S   G F++E+++ M   C  P++FPLSNPTSR+EA+P+D++ W+N
Sbjct: 368 DAIKIASPTILLGCSTVYGAFTKEVVEAMTASCKHPMIFPLSNPTSRMEAIPADVLAWSN 427

Query: 433 GEALVATGSPFDPVLHEGKTYPIVQCNNSYIFPGIGLGVLAANARRVTDEMLMESSRALA 492
           G AL+ATGSP  PV  +  TY I Q NN   FPGIGLGV+ A AR +T  ML  +++A+A
Sbjct: 428 GRALLATGSPVAPVEFDETTYVIGQANNVLAFPGIGLGVIVAGARLITRRMLHAAAKAIA 487

Query: 493 -SCSPLAINGHGPLLPPLESIHSVSKKIAFAVAKKAIEQGVAPEVTDEALEASIEQHFWQ 551
              +P   N    LLP ++++ ++S  +A AV + A++ GVA    D+  +A ++   W 
Sbjct: 488 HQANP--TNPGDSLLPDVQNLRAISTTVAEAVYRAAVQDGVASRTHDDVRQAIVDT-MWL 544

Query: 552 PVY 554
           P Y
Sbjct: 545 PAY 547