Pairwise Alignments

Query, 245 a.a., 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase from Vibrio cholerae E7946 ATCC 55056

Subject, 238 a.a., 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase from Methanococcus maripaludis JJ

 Score =  124 bits (312), Expect = 1e-33
 Identities = 76/238 (31%), Positives = 131/238 (55%), Gaps = 6/238 (2%)

Query: 1   MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGAGWLHLVDLTGAKNTAAR 60
           ++IPA+D+   + V+L QG+  +      +P E    +   GA  LHLVDL GA +    
Sbjct: 2   LVIPAVDMKNKKCVQLIQGNPDKKHVELDNPPEIAKKWVNEGAEMLHLVDLDGALDGKRV 61

Query: 61  QLNLIARLLASTPANIQIGGGVRSEQDVVDLLEAGAQRVVVGSTAVKQPQLVKSWIEKYG 120
               I  ++ ++   +QIGGG+RS +D   L+E GA++V++G+ AV+ P+++K   ++ G
Sbjct: 62  NDEFIEEIIKTSGVPVQIGGGIRSIEDAEYLVEKGAKKVIIGTIAVETPEIIKELSKRIG 121

Query: 121 AEKIVLALDINIDEQGTRKVAISGWQEDSGVTIEALIDDYLTVGLQHVLCTDISRDGTLA 180
           +EKI+++LD         KV I GW+E +  T   +      +G   +L T++  +G L 
Sbjct: 122 SEKIMVSLDAK-----DGKVVIKGWKEKTKYTPVKIGKILEEMGAGSILFTNVDSEGLLN 176

Query: 181 GSNVELYRDLCRQYPQVQFQSSGGIGSLADIEALKGTGVAGVIVGRALLDGKFTAQEA 238
           G N+E  ++L     ++   +SGG+ ++ D+  LK  GV GV+VG A+       +EA
Sbjct: 177 GINIEPTKELVENL-KIPIVASGGVTTIDDLLKLKEIGVYGVVVGSAIYKNLINLKEA 233



 Score = 31.2 bits (69), Expect = 2e-05
 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%)

Query: 2   IIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGAGWLHLVDLTGAKNTAARQ 61
           I+ +LD  +G+VV       G   + K  P +   +  + GAG +   ++          
Sbjct: 125 IMVSLDAKDGKVVIK-----GWKEKTKYTPVKIGKILEEMGAGSILFTNVDSEGLLNGIN 179

Query: 62  LNLIARLLASTPANIQIGGGVRSEQDVVDLLEAGAQRVVVGSTAVKQPQLVKSWIE 117
           +     L+ +    I   GGV +  D++ L E G   VVVGS   K    +K  IE
Sbjct: 180 IEPTKELVENLKIPIVASGGVTTIDDLLKLKEIGVYGVVVGSAIYKNLINLKEAIE 235