Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 740 a.a., Phosphoribosylformylglycinamidine synthase II (NCBI) from Rhodospirillum rubrum S1H

 Score =  150 bits (379), Expect = 4e-40
 Identities = 203/770 (26%), Positives = 332/770 (43%), Gaps = 119/770 (15%)

Query: 197 LGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKMIKNTFEQTPDYVLSAY 256
           +GR PN +EL +F+   SEHC +K               S  K +K T   T  +V+   
Sbjct: 34  MGREPNLVELGIFSVMWSEHCSYK---------------SSKKWLK-TLPTTAPWVIQGP 77

Query: 257 KDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPTAISPWPGASTGSGGEI 316
            +NA V+    +G               +    + K+E+HNHP+ I P+ GA+TG GG +
Sbjct: 78  GENAGVID---IG---------------DGLTAIFKMESHNHPSYIEPYQGAATGVGGIL 119

Query: 317 RDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPS--RIVNALDIMLEGPLGGA 374
           RD     +G +P A L     + LR           FG PS  R  + +  ++ G +GG 
Sbjct: 120 RD--VFTMGARPVANL-----NALR-----------FGDPSDPRTRHLISGVVAG-IGG- 159

Query: 375 AFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNIRAEHI-QKKEIPVG 433
            + N  G P + G       +V  HA          ++ A  +G  RA+ I       +G
Sbjct: 160 -YGNCVGVPTVGG-------EVNFHASFNGNN----LVNAMTVGVARADRIFYSAAAGIG 207

Query: 434 AKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFA--SVQRENPEMERRCQEVIDRCWQL 491
             ++ +G      G+ G   ++MAS + +ED +    +VQ  +P  E+    +I+ C +L
Sbjct: 208 NSVVYVGSKTGRDGIHG---ATMASAEFSEDSEEKRPTVQVGDPFTEKL---LIEACLEL 261

Query: 492 GDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPLEIWCNESQERY 551
            + + I  I D+GA G++++  E+ + G  G    L  VP  E GM+P E+  +ESQER 
Sbjct: 262 MNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVPMREEGMTPYELMLSESQERM 321

Query: 552 VLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDMPMDILLGKPPK 611
           ++ +      +  A+ ++    +A++G  T+   + L  +       D+P+D L    P+
Sbjct: 322 LMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVL--TWHGEVVGDLPIDPLAAASPE 379

Query: 612 MHREASTLKVSSPALERSGIE---LNEAVDRVLRLPAVAEKTFLITIGDRSVTGLVARDQ 668
             R      +++ A + SG E    +EA+ R++  P VA + ++    D  V G      
Sbjct: 380 YDRPWEPTPMAA-AADLSGAEDTPWSEALLRLIGCPDVASRRWIWEQYDHLVMG------ 432

Query: 669 MVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAITNIAATDI 728
                Q P  + AV         G AM+          D     + AV EA  N+ A   
Sbjct: 433 --NTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAEAWRNLTAVGA 490

Query: 729 GELKRIKLSANWMSPAGH--PGEDAGLYEAVKAVGEELCPALGITIPVGKDSMSMKTKWQ 786
             L  I  + N+ +P      G+  G  + +     E C AL   +  G  S+     + 
Sbjct: 491 RPL-AITDNMNFGNPEKPRIMGQFVGACQGI----SEACLALDFPVVSGNVSL-----YN 540

Query: 787 ENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRLGA---- 842
           E   Q  + +P    I     ++++  +V+  L+   GE  L+    G      GA    
Sbjct: 541 ETNGQAILPTP---TIGGVGVLDNVEASVSIALKA-AGEAILV---AGGFHGSTGAWLGQ 593

Query: 843 -TALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMAF 901
              L ++  +    P  VD AA+ K   D V+ L+    + A HD  DGGLLV LAEMA 
Sbjct: 594 SLFLREILGREEGAPPPVDLAAERK-VGDFVRGLILGASVTACHDLSDGGLLVALAEMAM 652

Query: 902 AGHCGIKANIETLGDDALAALFNEELGA-VVQVKNDELNAVLATLAAHGL 950
           AG  G +  +E   D+    LF E+ G  ++ V   + +AV+A   A G+
Sbjct: 653 AGDLGAELTLEGHPDN--GRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGV 700



 Score = 35.8 bits (81), Expect = 1e-05
 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 501 HDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPLEIWCNESQERYVLAVAAEDM 560
           HD+  GG+  AL E+   GD G +  L   P++            E Q RY+L VA  D 
Sbjct: 636 HDLSDGGLLVALAEMAMAGDLGAELTLEGHPDNGRLFG-------EDQGRYLLTVAEGDR 688

Query: 561 PLFDAICQRERAPYAVVG 578
               A  +    P  VVG
Sbjct: 689 DAVVAAAEAAGVPLRVVG 706