Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 993 a.a., phosphoribosylformylglycinamidine synthase II (TIGR) from Desulfovibrio vulgaris Hildenborough JW710

 Score =  182 bits (462), Expect = 1e-49
 Identities = 224/819 (27%), Positives = 346/819 (42%), Gaps = 106/819 (12%)

Query: 197 LGRNPNDIELMMFAQANSEHCRHKIFNA--DWTIDGVKQDKSLFKMIKNTFEQTP----- 249
           L  +P D E+   AQ  SEHC+HKIF++  D+      + +++  + K+  + T      
Sbjct: 228 LPADPTDAEVEALAQTWSEHCKHKIFSSRIDYENRETGRRETIDSLFKSCIQDTTKTIRA 287

Query: 250 -----DYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAH-ILMKVETHNHPTAIS 303
                D+  S +KDNA V+                      D H I +KVETHN P+A+ 
Sbjct: 288 RLGDKDFCRSVFKDNAGVIA-------------------FNDTHDICIKVETHNSPSALD 328

Query: 304 PWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQP-WESDFGKPSRIVNA 362
           P+ GA TG  G  RD   TG+G    A LV     N  +  F  P WE +   P R+++ 
Sbjct: 329 PYGGALTGIVGVNRDPMGTGMG----ANLV----CNTDVFCFASPFWEGEL--PPRLLHP 378

Query: 363 LDIMLEGPLGGAAF-NNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNIR 421
             + LEG   G     N+ G P + G    +E++             KP++  G +G I 
Sbjct: 379 RRV-LEGVREGVEHGGNKSGIPTVNGSI-VFEDRYLG----------KPLVYCGTVGMIP 426

Query: 422 AEHIQK----KEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEM 477
           A+   K    KE   G  ++++GG    IG  G   ++ +S +  E     +VQ  +P  
Sbjct: 427 AQVAGKPGYTKEARPGDAIVMVGG---RIGKDGIHGATFSSEELHEGSPATAVQIGDPIT 483

Query: 478 ERRCQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGM 537
           +R+  + I R   +G    I    D GAGG+S+++ E+  D   G +  L   P    G+
Sbjct: 484 QRKMYDCIMRARDMGLYTAIT---DNGAGGLSSSVGEMAQD-TGGCRLDLARAPLKYDGL 539

Query: 538 SPLEIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEER--HLTLEDSHFAN 595
            P EI  +E+QER  LAV  + +  F  +         V+GE T+    H+T  D   A 
Sbjct: 540 RPWEILLSEAQERMTLAVPQDKLEAFMRLASEMDVEATVLGEFTDSGYFHITFGDRQVAY 599

Query: 596 TPIDMPMDILLGKPPKMHREASTLKVSSP--ALERSGIELNEAVDRVLRLPAVAEKTFLI 653
               + MD L    P++  +A   + + P   ++    E    + R++    +  K ++I
Sbjct: 600 ----LDMDFLHDGVPQLQLKAVWERPAHPEGRIDLPEEEQGPFLRRMMGSLNICSKEYVI 655

Query: 654 TIGDRSVTGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASAR 713
              D  V G      +VG  +   A+ AV     DS  G  +S G     +  D      
Sbjct: 656 RQYDHEVKGGSVVKPLVGVKRDGPADAAVVRPLLDSESGIVLSHGICPKFSDYDAYWMMA 715

Query: 714 LAVGEAITNIAATDIGELKRIKLSAN--WMSPAGHPGEDAGLYEAVKAVG-----EELCP 766
            A+ EA+ N  A   G+   +    N  W  P        G Y+  + V      E  C 
Sbjct: 716 NAIDEAVRNAVAVG-GDPDFMSGVDNFCWCDPVQSDKTPDGHYKLAQLVRANRALEHFCL 774

Query: 767 ALGITIPVGKDSMSMKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGET 826
           A G+    GKDSM    K    G   +++ P +++ +    ++D+ +TVT   +   GE 
Sbjct: 775 AYGVPCVSGKDSM----KNDYTGGGTKISIPPTVLFSVMGVIDDVNRTVTSDFKR-AGER 829

Query: 827 SLILIDLGNGQNRLGATALAQVYKQLGDKPADVD--NAAQLKGFFDAVQTLVRNDKLVAY 884
             +   LG  +  +  +  AQV   LG   ADV   +A      + A+   +R   + A 
Sbjct: 830 IYL---LGLTRREMAGSEAAQV---LGISCADVPQVDAPAALARYRALYGAIRAGLVTAC 883

Query: 885 HDKGDGGLLVTLAEMAFAGHCGIK---ANIETLGDDALAALFNEELGA--VVQVKNDELN 939
           HD  DGGL V LAEM   G  G +   A +   GD     L   E  +  +V V+  + +
Sbjct: 884 HDLSDGGLAVALAEMCLGGRLGARCDLARVPVCGDMTTTELLYSESASRLLVSVRPADAD 943

Query: 940 AVLATLAAHGLEACAHVIGEVEASDRL-LITCGEEVLIE 977
           A  A  A     AC   +GEV A  RL L T G  ++ E
Sbjct: 944 AFEAAFAGQHY-AC---VGEVTADGRLTLETKGTAIVSE 978