Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1234 a.a., putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482

 Score =  650 bits (1677), Expect = 0.0
 Identities = 452/1268 (35%), Positives = 665/1268 (52%), Gaps = 76/1268 (5%)

Query: 45   ELNPQELEKLEKLLTYGPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKR 104
            +L P E  KL  L  +G  + E E       V PR   I+PWS+ A +I  N GL  I R
Sbjct: 20   QLTPDESNKLCWL--FGEAVTESEENLKGCFVGPRREMITPWSTNAVEITQNMGLEDILR 77

Query: 105  LERGTAYYVEAETALTAAQIATLEALLHDRMMEVVFAELTDAQQLFSV-AEPAPMSQVDV 163
            +E    + V+ E A             +D M++ ++  L   Q +F+   +P P+  ++ 
Sbjct: 78   IEE--YFPVKDENAD------------YDPMLQRMYKGLD--QNVFTTNRQPEPIVSIE- 120

Query: 164  LAGGRRALEEANVSLGLALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFN 223
                   LE  N   GLAL+++E+DYL +    LGR   D E+  FAQ NSEHCRHKIF 
Sbjct: 121  ------DLEAYNEKEGLALSKEEMDYLKKVENDLGRKLTDSEVFGFAQINSEHCRHKIFG 174

Query: 224  ADWTIDGVKQDKSLFKMIKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYH 283
              + IDGV+Q+ SLF+MIK T ++ P+ ++SAYKDN A   G  V +F P   S+   + 
Sbjct: 175  GTFIIDGVEQESSLFQMIKKTTQENPNKIISAYKDNVAFAEGPVVEQFAPADHSKPDFFQ 234

Query: 284  HEDAH--ILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLR 341
             +D    I +K ETHN PT + P+ GASTG+GGEIRD    G G  P AG   + TS  R
Sbjct: 235  VKDIKSVISLKAETHNFPTTVEPFNGASTGTGGEIRDRMGGGKGSWPIAGTAVYMTSYPR 294

Query: 342  IPGFEQPWESDFGKPSRIVNALD-IMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHA 400
                 + WE        +    + I+++   G + F N+FG+P + G   T+E    +  
Sbjct: 295  TDEGRE-WEDILPVRKWLYQTPEQILIKASNGASDFGNKFGQPLICGSVLTFEHTENN-- 351

Query: 401  GEEVRGYHKPIMIAGGMGNIRAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQ 460
              EV GY K IM+AGG+G        K     G K++V+GG    IGLGGG+ SS+ +G+
Sbjct: 352  --EVYGYDKVIMLAGGVGYGTQRDCLKGTPEAGNKVVVIGGDNYRIGLGGGSVSSVDTGR 409

Query: 461  SAEDLDFASVQRENPEMERRCQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGD 520
             +  ++  +VQR N EM++R   V+ R     D NP+  IHD G+ G  N L ELV +  
Sbjct: 410  YSSGIELNAVQRANAEMQKRANNVV-RALCEEDVNPVVSIHDHGSAGHVNCLSELVEEC- 467

Query: 521  RGGKFQLRNVPNDEPGMSPLEIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEA 580
             GG   +  +P  +  +S  EI  NESQER  L +  E +     I +RERAP  VVGE 
Sbjct: 468  -GGLIDMSKLPIGDKTLSAKEIIANESQERMGLLIKEEAIEHVRKIAERERAPMYVVGET 526

Query: 581  TEERHLTLEDSHFANTPIDMPMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRV 640
            T +   + + +     P D+ ++ + G  PK +    T++      E    +L+E +  V
Sbjct: 527  TGDHRFSFQQADGVR-PFDLAVEQMFGSSPKTYMIDKTVERHYEMPEYELPKLHEYLTNV 585

Query: 641  LRLPAVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGER 700
            L+L AVA K +L    DRSVTG VAR Q  G  Q+P+++C V A  +    G A S+G  
Sbjct: 586  LQLEAVACKDWLTNKVDRSVTGKVARQQCQGELQLPLSDCGVVALDYRGEKGIATSIGHA 645

Query: 701  TPVALLDFGASARLAVGEAITNIAATDIGE-LKRIKLSANWMSPA-GHPGEDAGLYEAVK 758
               AL D  A + L+V EA+TN+    + E +  I LSANWM P     GEDA LY AVK
Sbjct: 646  PQAALADPAAGSILSVSEALTNLVWAPMAEGMDSISLSANWMWPCRSQEGEDARLYTAVK 705

Query: 759  AVGEELCPALGITIPVGKDSMSMKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQ 818
            A+ +  C AL I +P GKDS+SM  K+  NGE+  V SP ++I++A   V D++K V+P 
Sbjct: 706  ALSD-FCCALQINVPTGKDSLSMTQKYP-NGEK--VISPGTVIVSAGGEVSDVKKVVSPV 761

Query: 819  LRTDLGETSLILIDLGNGQNRLGATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRN 878
            L  +  +T+L  ID    + +LG +A AQ   ++GD    V +A   +  F AVQ LV  
Sbjct: 762  LVNN-EKTTLYHIDFSFDELKLGGSAFAQSLGKVGDDVPCVQDAEYFRDAFLAVQELVNK 820

Query: 879  DKLVAYHDKGDGGLLVTLAEMAFAG-HCGIKANIETLGD-DALAALFNEELGAVVQVKND 936
              ++A HD   GGL+ TL EM FA    G++ +++ + + D +  LF E  G V+Q+ + 
Sbjct: 821  GLILAGHDISAGGLITTLLEMCFANVEGGMEISLDKMKEQDIIKILFAENPGIVIQISDK 880

Query: 937  ELNAVLATLAAHGLEACAHVIGEVEASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQA 996
                V   L   G+      +G+      +L++ G+    +     +R +W   ++ +  
Sbjct: 881  HKEEVKKILEDAGVGFVK--LGKPTDERHILVSKGDATY-QFGVDYMRDVWYSSSYLLDR 937

Query: 997  LRDNSACADQEFAAKQDNRD-----PGLNAKLT-YDVQADVAAPYIAKGVRPKMAILREQ 1050
             +  + CA + F   +         PG   KL+ Y +  D   P    GVR   AI+RE+
Sbjct: 938  KQSMNGCAKKRFENYKMQPVEFAFMPGFKGKLSQYGITPDRRTP---SGVRA--AIIREK 992

Query: 1051 GVNSHVEMAAAFDRAGFDAVDVHMSDILTGQTVLDAYQGLVACGGFSYGDVLGAGEGWAK 1110
            G N   EMA +   AGFD  DV M+D+++G+  L+    +V CGGFS  DVLG+ +GWA 
Sbjct: 993  GTNGEREMAYSLYLAGFDVKDVTMTDLISGRETLEDVNMIVYCGGFSNSDVLGSAKGWAG 1052

Query: 1111 SILFNAQAREQFEQFFQRKDTFSLGVCNGCQMLSNLRDLIPGAELWPRFVRNESDRFEAR 1170
              LFN +A+E  ++F+ R+DT SLG+CNGCQ++  L  + P  E   + + N+S +FE+ 
Sbjct: 1053 GFLFNPKAKEALDKFYAREDTLSLGICNGCQLMMELGLINPEHEKKGKMLHNDSHKFEST 1112

Query: 1171 FSLVEVQKSPSLFFSEMAGSRMPIAVSHGEGRVEVRDAQHLAAIEQSGTVAIRFVDNFGQ 1230
            +  + +  + S+ F  ++GS++ I V+HGEG+  +   +     +Q   VA    D    
Sbjct: 1113 YVGLTIPTNRSVMFGSLSGSKLGIWVAHGEGKFSLPYDE-----DQYNVVAKYSYDE--- 1164

Query: 1231 PTQAYPSNPNGSPNAITGLTTQDGRVTIMMPHPERVFRTVANSWHP---DNWGENGAWMR 1287
                YP NPNGS  +I GL + DGR   MMPH ER      N  +P    N  +   W+ 
Sbjct: 1165 ----YPGNPNGSDYSIAGLASADGRHLAMMPHLERAIFPWQNGCYPADRKNSDQITPWIE 1220

Query: 1288 MFQNARKY 1295
             F NARK+
Sbjct: 1221 AFVNARKW 1228