Pairwise Alignments

Query, 445 a.a., MATE family efflux transporter from Vibrio cholerae E7946 ATCC 55056

Subject, 454 a.a., putative Na+-driven multidrug efflux pump (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482

 Score = 97.1 bits (240), Expect = 1e-24
 Identities = 94/412 (22%), Positives = 175/412 (42%), Gaps = 35/412 (8%)

Query: 5   SIYRQFVRYTIPTVAAMLVNGLYQVVDGIFIGHYVGAEGLAGINVAWPVIGTILGIGMLV 64
           S+ +  ++Y +P + A ++  LY   D   +G Y  +  +A + +   V+ TI GI  ++
Sbjct: 10  SVPKVLLQYAVPFLIANVLQALYGGADLFVVGQYDDSASVAAVAIGSQVMQTITGI--IL 67

Query: 65  GVGTGALASIKQGEGHPDSAKRILATGLMSLLLLAPIVAVILWFMADDFLRWQGAEGRVF 124
           G+ TG    I    G  D  K     G  S + L  I+ V+L  +   F       GR+ 
Sbjct: 68  GITTGTTVLIAIATGAKDDKKVAFTIG--SSVWLFSIIGVLLTLVMVVF------HGRIA 119

Query: 125 EL----------GLQYLQVLIVGCLFTLGSIAMPFLLRNDHSPNLATLLMVIGALTNIAL 174
           EL             Y+ V   G LF +G   +  +LR           + +  + NI L
Sbjct: 120 ELMHTPIEAMADTKSYILVCSAGILFIVGYNVVCGILRGLGDSKTPLYFVALACVINIVL 179

Query: 175 DYLFIAWLQWELTGAAIATTLAQVVVTLLGLAYFFSARANMRLTRRCLRLEWHSLPKIFA 234
           D++ + +     TGAA+AT  AQ V  ++ L + +    +   TR+ +RL  +   K+  
Sbjct: 180 DFILVGYFHLGATGAAVATITAQGVSFMISLWFLYRHGFHFEFTRKDIRLNRNLAKKVMT 239

Query: 235 IGVSSFFMYAYGSTMVALHNTLMIEYGNAVMVGAYAVMGYIVTIYYLTVEGIANGMQPLA 294
           +G       A    +  L  T+++     +   +  V+  I+    L    I++ +  + 
Sbjct: 240 LGAPIALQDAL-INISFLIITVIVNQMGVIASASLGVVEKIIVFAMLPPMAISSAVATMT 298

Query: 295 SYHFGARNYDHIRKLLRLAMGIAVLGGMAFVLVLNLFPEQAIAIFNSSDSELIAGAQMGI 354
           + ++GA     + + L   +GIA + G++  +     PE   A F + D+ +++ A    
Sbjct: 299 AQNYGAGLIQRMNRCLASGIGIAFVFGVSVCVYSQFLPETLTAFF-TKDAAVVSMA---- 353

Query: 355 KLHLFAMYLDGF----LVVSAAYYQSTNRGGKAMFITVGNMSIMLPFLFILP 402
                A YL G+    +VVS  +  ++   G+   +     S++  FLF +P
Sbjct: 354 -----AEYLRGYSIDCIVVSFVFCINSYFSGQGNSLFPMIHSLIATFLFRIP 400