Pairwise Alignments

Query, 1039 a.a., AcrB/AcrD/AcrF family protein from Vibrio cholerae E7946 ATCC 55056

Subject, 1037 a.a., Multidrug efflux pump subunit AcrB from Enterobacter sp. TBS_079

 Score =  250 bits (638), Expect = 4e-70
 Identities = 234/1049 (22%), Positives = 452/1049 (43%), Gaps = 65/1049 (6%)

Query: 18   LLVFILVAGVATYLTIPKESSPDVTIPIIYVSVSHQGISPSDAERLIVRPLEQEMRSIEG 77
            L + + + GV    ++P E  PD+  P + V+ ++ G S    E  + + +EQ M  ++ 
Sbjct: 15   LAILLCLTGVLAITSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDN 74

Query: 78   VKEMTATASE-GHASVVLEFNVGVDLAKAMADVRDAVDLAKPKLPADSDEPTVNEVTLAA 136
            +  M++ +S  G A+V L F  G D  +A+  V++ +  A  KLP       V  V    
Sbjct: 75   LMYMSSQSSATGQATVTLSFTAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVT-VRKTG 133

Query: 137  EQPVLSVVLYGTV----PERTTVLIARQLRDKLESFRQILSVDIAGDREEIVEIIVDPLL 192
            +  +L++    T      +     +A  ++D L     +  +D  G +  +  I +DP  
Sbjct: 134  DTNILTIAFVSTDGSMDKQDIADYVASNIQDPLSRINGVGDIDAYGSQYSM-RIWLDPDK 192

Query: 193  MESYGLDQSDIYNLIALNNRVVAAG------FVDTGYGRFSVKVPSVFESLKDVLELPIK 246
            + S+ +  +D+ + I   N  +A G       V+      ++   S+ ++      + ++
Sbjct: 193  LNSFQMTATDVTDAIKSQNAQIAVGQLGGTPSVEKQALNATINSQSLLQTPDQFRNITLR 252

Query: 247  V--EGKQVITFGDVATVRKSFRDPESFARLDGKPAIVLDIKKRSGENIIETVELVKAVLG 304
            V  +G +V   GDVATV       +  +R +G PA  L IK  SG N + T +LV   L 
Sbjct: 253  VNQDGSEV-RLGDVATVEMGAEKYDYLSRFNGNPASGLGIKLASGANEMATAKLVLDRLD 311

Query: 305  EAQARDDWPNNLLVKTIWDESEDVKLMLNDLQNNILSAIILVVVVIIAIL-GVRTSLLVG 363
            E    + +P+ L  K  ++ +  VK  + D+   +L AI LV +V+   L   R +L+  
Sbjct: 312  ELS--NYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPT 369

Query: 364  VSIPGSFLTGLLVLAVFGLTVNIVVLFALIMAVGMLVDGAIVVTEFADRRM-QEGMHRSE 422
            +++P   L    VL  FG ++N + +FA+++A+G+LVD AIVV E  +R M +EG+   +
Sbjct: 370  IAVPVVLLGTFAVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLSPRQ 429

Query: 423  AYRDAAKRMAWPITASTATTLAAFAPLLFWPDVTGEFMKYLPLTLMATLTASLVMALLFV 482
            A R +  ++   +        A F P+ F+   TG   +   +T+++ +  S+++AL+  
Sbjct: 430  ATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMVLSVLVALILT 489

Query: 483  PVLGSLFGRP-QKVTQANQARMVALHNGDFSQATGITKAYYSTLAIAIRHPIKILCGALL 541
            P L S   +P  K  Q  Q       N  F++       Y S +   +   ++ +   ++
Sbjct: 490  PALCSTLLKPLHKGEQHGQKGFFGWFNRMFNRNAA---RYESAVGKVLHRSLRWMLIYVV 546

Query: 542  MSAAIAFAYGKAGLGAEFFPEVDPPFFSVKVRSYGDLSLNEKDRIMSDIEQVMLGHDE-- 599
            +   + + +    L   F P  D   F+  V+     +  +  +++  +EQ     ++  
Sbjct: 547  LLGGMVWLF--LHLPTSFLPMEDRGMFTTSVQLPSGATQQQTLKVVEKVEQYFFTQEKDN 604

Query: 600  ----FESVYTRTGGDDE-IGVVQITPVDWQYRRSVKAIIEE-LEQVTDTFPGVEIEYKFP 653
                F +V +  GG+ + +  + +   DW  R +        +E+ T  F  +     F 
Sbjct: 605  VVSVFSTVGSGPGGNGQNVARMFVRLKDWDERDTKTGTAAAIIERATHAFTKINEARVFA 664

Query: 654  DAGPPVE-------HDLEIEISARVADDLDKAAQQVRLWAEANPA-LTNLSDNGSKPGID 705
             + P +         D+E++  A        AA+   L      A LT +  NG      
Sbjct: 665  SSPPAISGLGSSAGFDMELQDHAGAGHTALMAARDKLLALAGKDADLTRVRHNGLDDSPQ 724

Query: 706  WKIDIRRDDASRFAADATLVGNTVQFVTNGLKIGDYLPDDSDEEVDILVRYPSEYR---- 761
             ++DI +  A         + +T+Q       + D++  D      + V+  + +R    
Sbjct: 725  LQVDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFM--DRGRVKKVYVQSAAPFRMLPN 782

Query: 762  DIGRFDQLRVKTAQGLVPLTNFAQIIPEQKQDTIHRVDGRRVISVMADLKEGYNLALELP 821
            DI R+       A G+VP + FA    E     + R +G   + ++ +   G +    + 
Sbjct: 783  DINRW--FVRNNAGGMVPFSAFASSHWESGSPRLERYNGYSAVEIVGEAAPGVSTGTAMD 840

Query: 822  AIEQALRELNLPSSVEFRIRGQNEEQEHSAVFLEKAFMVALAAMAIILITQFNSFYQAFL 881
             +E+ +++  LP+         + ++  S       + ++L  + + L   + S+   F 
Sbjct: 841  TMEKLVQQ--LPAGFGLEWTAMSYQERLSGAQAPALYALSLLVVFLCLAALYESWSVPFS 898

Query: 882  ILTAVIFSTVGVFAGLLIFQKPFGIIMSGIGVIALAGIVVNNNIVLIDTYNQLLKRGLSR 941
            ++  V    +G      +      +    +G++ + G+   N I++++  N++  +G   
Sbjct: 899  VMLVVPLGVIGALLATWMRGLENDVYFQ-VGLLTVIGLSAKNAILIVEFANEMNAKGHEL 957

Query: 942  EEAILRTGVQRLRPVLLTTVTTILGLLPMVLEMNIDIINQKIEFGAPSTQWWSQLATAVA 1001
              A L    QRLRP+L+T++  + G+LPM               GA S+   + + T V 
Sbjct: 958  MAATLHACRQRLRPILMTSLAFVFGVLPMATST-----------GAGSSSQHA-VGTGVM 1005

Query: 1002 GGLAFATVLTLVLTPCLLMLGRRRKGVSE 1030
            GG+  ATVL +   P   +L RRR  + E
Sbjct: 1006 GGMISATVLAIYFVPLFFVLVRRRFPLKE 1034