Pairwise Alignments

Query, 524 a.a., glutamate--cysteine ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 518 a.a., glutamate--cysteine ligase from Klebsiella michiganensis M5al

 Score =  566 bits (1459), Expect = e-166
 Identities = 279/513 (54%), Positives = 360/513 (70%), Gaps = 2/513 (0%)

Query: 5   AERLQTVANKPEVFQKFSRGLERESLRYTPEGALTQTPHPKALGAALTHRWITTDFAESL 64
           ++ L  +   P+  Q   RGLERE+LR   +G L  T HP+ALG+ALTH+WITTDFAE+L
Sbjct: 6   SQALAWLEKNPQALQGIQRGLERETLRVNADGTLATTGHPQALGSALTHKWITTDFAEAL 65

Query: 65  LEFITPVSHEVDTLLAQMSDIHHFAQTKLGDEKLWPLSMPCYVGSEEGIVLAQYGSSNTG 124
           LEFITPV  ++  +L  M D+H +    +GDE++WPLSMPCY+   + I LAQYG+SN G
Sbjct: 66  LEFITPVDGDIQHMLTFMRDVHRYTARHIGDERMWPLSMPCYIAPGQDIELAQYGTSNIG 125

Query: 125 KMKTLYREGLKRRYGSLMQIISGVHFNFSFPESFWDALFGEQEESARQASKSAAYFGVIR 184
           ++KTLYREGLK RYG+LMQ ISGVH+NFS P +FW A  G ++  + + + SA YF  IR
Sbjct: 126 RLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVEDAESGKEAISAGYFRSIR 185

Query: 185 NYYRFGWLIPYLFGASPALCSSFLQGRKTDLPFESIGKTLY-LPYATSLRLSDLGYTNSA 243
           NYYRFGW+IPYLFGASPA+CSSFLQG+ T LPF+     +Y LPYATSLRLSDLGYTN +
Sbjct: 186 NYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFQEASNGMYYLPYATSLRLSDLGYTNKS 245

Query: 244 QSVLQIGFNSIEQYLQGLNEAIRTPSAEFAKLGVKVEGEYRQLNSNVLQIENELYAPIRP 303
           QS L I FN + +Y+ GL  AI+TPS E+  +G++ +G+  Q+NSNVLQIENELYAPIRP
Sbjct: 246 QSNLGITFNDLYEYVSGLKRAIKTPSEEYENIGLEKDGKRLQINSNVLQIENELYAPIRP 305

Query: 304 KRVTQSGERPSQALARAGVEYIEVRSLDVNPFSPIGINEDQVRFLDLFLAWTALSDSDPM 363
           KRVT+SGE PS AL R G+EYIEVRSLD+NPFSPIG++E QVRFLDLF+ W  L+D+  M
Sbjct: 306 KRVTRSGETPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEM 365

Query: 364 DGCELACWRDNWRKVVLEGRKPGLELQIGCHGEVLTLQAWAKRVFADLRVIAETMDAALG 423
              EL C R NW +V+LEGRKPGL L IGC      L    K +F DLR +A+T+D+  G
Sbjct: 366 SSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLAQVGKDLFRDLRRVAQTLDSIHG 425

Query: 424 GDAYQAVCAKLETWIENPELTLSAQILAEIKQHGGLGKTGCALGNEYRAVNLQHQYQFYS 483
             AYQ  C +L    +NPELT SA+IL  + +  G+G TG  L + YR +  +   +  S
Sbjct: 426 CQAYQQACDELVACFDNPELTFSARILRSMLEE-GIGGTGRELADRYRTMLREEPLEILS 484

Query: 484 QDEMEQEVRRSTQAQADIEAKETLNFDAYLTQY 516
           + +   E   S Q Q  +EA ++  F+A L ++
Sbjct: 485 EADFVAEREASLQRQEKVEAADSEPFEALLARH 517