Pairwise Alignments

Query, 860 a.a., alanine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 892 a.a., alanine--tRNA ligase from Methanococcus maripaludis JJ

 Score =  239 bits (611), Expect = 4e-67
 Identities = 241/914 (26%), Positives = 381/914 (41%), Gaps = 186/914 (20%)

Query: 6   DEVRRAFLSFFESKGHQIVESSSLVPAN-DPTLLFTNAGMNQFKDCFL-GLEKRAYTRAT 63
           +E+ + F +FF+ KGH  V+ S +V       +L T A +  F+     GL K       
Sbjct: 62  NEMVKEFTNFFDEKGHTPVKRSPVVAKRWRDDILLTIASIAVFQPWVTSGLVKPVKNPLV 121

Query: 64  TAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKEDAIQYAWEFLTDVLQLPK 123
            AQ C+R     ND++NVG T RH T F M  + +F    K+D     +++ TD      
Sbjct: 122 IAQPCIRL----NDIDNVGRTGRHLTCFTMGAHHAFNS--KDD-----YKYWTD------ 164

Query: 124 ERLLVTVYETDDEAFDIWNKKVGIPADRIIRIGDKKGGKKFDSDNFWQMGDTGPCGPCTE 183
                   +T +  F++  K++GI    I  I           +++W+ G  G  GPC E
Sbjct: 165 --------KTVEYCFELM-KRLGIDGKTITFI-----------ESWWEGG--GNAGPCYE 202

Query: 184 IFYDHGDHIWGGPPGSPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERI 243
           +   HG                  +E+   VFMQ+ +  +   E +P   VDTG GIER 
Sbjct: 203 VI-THG------------------VELATLVFMQYKKIGND-YEEIPLKIVDTGYGIERF 242

Query: 244 SAIMQGVHSNYEI----------------DVFQTLIKAAADAIGYQDLTNQS-LRV---- 282
           +   QG  + YE                 +V + ++  +A   G  D+ N   LRV    
Sbjct: 243 AWASQGTPTVYESLFSEIIEKLKEDAGIPEVDEKIMAESATLAGLMDIENVGDLRVLRQK 302

Query: 283 ------------------------VADHIRSCAFLIVDGVMPSNEGRGYVLRRIIRRAVR 318
                                   +ADH R  +F+  DG++PSN   GY+ R ++R+ +R
Sbjct: 303 VAEKIGMDVDELDKLISPLEYIYAIADHTRCLSFMFGDGIVPSNVKEGYLARLVLRKTLR 362

Query: 319 HGNKLGAQGAFFHKLVGPLAEVMGTAGVELKKQQALVEKVLRIEEENFGRTLDRGMSILN 378
           +  K+G   +    ++    E M     EL   +  +  VL  EE+ + +T++RG  I+ 
Sbjct: 363 YMEKIGISMSI-KDIISMQLENMKEIYPELSGMKEYIMDVLDSEEKKYIQTVNRGRGIVE 421

Query: 379 DALDQLSGQVLDGETVFKLYDTYGFPADLTNDVARERGFS----------------IDEA 422
                 S   LD   + +LYD+ G P ++  DV  E                    + E 
Sbjct: 422 RMAASKSEITLDD--LIELYDSNGLPPEIVKDVVDELNKKGKKTIAITVPDNFYTIVAER 479

Query: 423 GFEQAMEEQRQRAREAGQFGTDYNSLI--KSATNTEFCGYTASRGQSVVREMFVEGAEVS 480
             E+  EE     +E  +       L+  K  T  EF                    E  
Sbjct: 480 HEEEKPEEVVSTKKELPELEVSETELLFFKHPTQVEF--------------------EAK 519

Query: 481 TLSAGDKAIIVLDNTPFYAESGGQCGDTGVLKTDAGIFHVEDTQKLGNAIAHHGVIAQGV 540
            L   +K  IVLD T FYAE GGQ  D G L        V D QK  N I  H V     
Sbjct: 520 ILKIAEK-YIVLDKTLFYAEGGGQKYDIGQLND----IEVIDVQKK-NGIVFHKVSDISK 573

Query: 541 LATGDQVDAIVDEKRRAAISLNHSATHLLHAALRKVLGEHVAQKGSLVRAETLRFDFSHL 600
              GD V   V+   R  +  NH+ATH+++AA  +VLG+HV Q GS V  E  R D +H 
Sbjct: 574 FKEGDTVKGAVNWDNRLKLMRNHTATHVINAAATRVLGKHVWQTGSNVDTEKGRLDITHY 633

Query: 601 EAMTAAEIKEVERLVNQEVRRNHSIETNIMNIDEAKAKGAMALF--GEKYDDQVRVLSMG 658
           E ++  ++KE+ER+ N+ V     + +  M+ ++A+ K    ++  G    D +R++ + 
Sbjct: 634 ERISREQVKEIERIANEIVLSKMPVNSTFMDRNDAEQKYGFTIYQGGVVPGDTLRIIEIE 693

Query: 659 DFSTELCGGIHASNTGDIGLFKIISEGGIAAGIRRIEAVTGEGAL--------------D 704
               E CGG H SNT ++G  K++    I  G+ R+E  TG G++              +
Sbjct: 694 GTDVEACGGTHCSNTSEVGYIKVLKTERIQDGVERLEYSTGMGSVSEIASLEDTLIDSAE 753

Query: 705 YLDAQQAQHDAKVSEMAAKAKLLEKEIQQLKDKLAAKESAGLINQVKQIAGVNVLVAQLN 764
            L     Q    V     + K  +K I++L+ K+       L ++ + +    VLV Q+N
Sbjct: 754 ILGIPNDQLPKTVKRFFEEWKEQKKTIEELQKKVGELVKYELADKFENVGNYEVLVEQVN 813

Query: 765 GADNKALRGMVDDLKNQLSSGIIMLGNVAEGKVGLIAGVTND--LTNKVKAGELVNMVAL 822
           G  N+ +                +  N+A G   ++    ND  L  + +  E+     +
Sbjct: 814 GTPNELMS---------------IADNLAVGNKLIVLMNENDYLLCKRGENVEISMKDLI 858

Query: 823 QVGGKGGGRPDMAQ 836
           +  GKGGG+ ++AQ
Sbjct: 859 RNIGKGGGKDNLAQ 872