Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 650 a.a., DNA mismatch repair protein (RefSeq) from Shewanella amazonensis SB2B

 Score =  470 bits (1210), Expect = e-137
 Identities = 280/619 (45%), Positives = 390/619 (63%), Gaps = 26/619 (4%)

Query: 1   MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNG 60
           M I++LP +LANQIAAGEVVERPASV+KELVENSLDAGATR+DID++KGG+KLIRIRDNG
Sbjct: 1   MAIQVLPPQLANQIAAGEVVERPASVIKELVENSLDAGATRVDIDIDKGGSKLIRIRDNG 60

Query: 61  SGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEA 120
            GI K EL LAL+RHATSK+ TL+DLEAI+S GFRGEALASISSVSRLTLTSRT  Q EA
Sbjct: 61  GGIPKAELALALARHATSKVQTLEDLEAILSFGFRGEALASISSVSRLTLTSRTTEQAEA 120

Query: 121 WSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIAL 180
           W AY+EG ++A+++ PAAHPVGTT+EV DLFFNTPARR+FL+++KTEFTHIDE LKRIAL
Sbjct: 121 WQAYAEGSEVAIRVMPAAHPVGTTIEVADLFFNTPARRRFLKSDKTEFTHIDEWLKRIAL 180

Query: 181 SRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWI 240
            R DV F+L HNGK VRQYR A T  Q  +RLA V G  F    ++++ +H G+ L G++
Sbjct: 181 IRSDVHFSLSHNGKPVRQYRCAATDTQYLQRLAQVAGRAFADSAIKVDCQHDGMGLSGYL 240

Query: 241 TTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDV 300
            +P       D  Y YVNGR++RD+L+NHA+RQ++      +Q A +VL + LDPHQVDV
Sbjct: 241 QSP-ALSDMVDCHYFYVNGRLIRDRLVNHAVRQAFGELGTFEQPA-FVLSLTLDPHQVDV 298

Query: 301 NVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVP 360
           NVHPAKHEVRFHQAR VHDFI Q L SAL Q   +        A   P    E      P
Sbjct: 299 NVHPAKHEVRFHQARYVHDFILQVLQSALSQMQDLPLAEELPRAQESPASVREHTAGYAP 358

Query: 361 MIDTTQQERVWQA---VQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTG 417
              T  ++   +A   + + PD  +++ R  ++  S      +  +S    ++ + + TG
Sbjct: 359 Y--TFNRDAATEAAGVLSSLPD-TQRSQRQPEKAASGQRSSVDAGLSQ-GSSAHRASQTG 414

Query: 418 KERYGSAS---VSKKEAAVYQTLMQ-----TPDLSDEEPSTA---STIVSSIEAVKANIA 466
             + G+A+    S++  + Y    Q        LS ++   A   + ++ + E V  + +
Sbjct: 415 LGQSGNAATFETSERHGSGYSGAGQGQRYVRDQLSGQQRQAAQYYAELLHTPEVVSTSGS 474

Query: 467 IEKLGKAIQVVAGQYLLMSSPQGCVLISLYQ-AQQLKLRGLLNAQHGALKAQPLLVPLAL 525
           ++       ++AG+Y +++  +   L+S+   A+ L ++ +L+     L  QPLL+P+A+
Sbjct: 475 LQAGLPMPPLLAGRYWVLAQDEHLRLLSISDAAKALVVQEILSKLPTGLVGQPLLMPVAV 534

Query: 526 KLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASC 585
             +     +     S L +LG+EL  R    +++  VP  LR   L +L+P+ L +    
Sbjct: 535 AADADWTMILAERESLLRRLGLELTIR-YQQLIIKKVPPYLRDSQLAKLIPEFLEWI--- 590

Query: 586 SESQALSHQALADWLTQRI 604
            + +  + +AL  WL Q +
Sbjct: 591 -KLEVPADEALCHWLAQYV 608