Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 621 a.a., DNA mismatch repair protein MutL (RefSeq) from Dinoroseobacter shibae DFL-12

 Score =  263 bits (672), Expect = 2e-74
 Identities = 206/608 (33%), Positives = 300/608 (49%), Gaps = 92/608 (15%)

Query: 3   IRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNGSG 62
           IR L     N+IAAGEV+ERPAS VKELVEN+LDA A +I+I    GG  L+R+ D+G G
Sbjct: 21  IRQLDEAAINRIAAGEVIERPASAVKELVENALDAQARQIEIAYADGGKTLLRVTDDGIG 80

Query: 63  IDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEAWS 122
           I   +L LAL+RHATSKI   D L  I + GFRGEAL S+ +V RLT+ SR    E A  
Sbjct: 81  IAAGDLPLALARHATSKIDGADLLN-IHTFGFRGEALPSLGAVGRLTIASRAAGAEAAEV 139

Query: 123 AYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIALSR 182
               GR   V+  PAA   GT V + DLF  TPAR KFLR+++ E   I E+++R+A++ 
Sbjct: 140 TVEGGRMGPVR--PAALNRGTVVTLRDLFSATPARLKFLRSDRAEVQAIGEVVRRLAMAE 197

Query: 183 FDVSFTLRH-----NGKIVRQYRAATTLPQQ-------EKRLAAVCGNPFVQHMLRIELE 230
             V FTLR       G++   +R A   P+Q        +RL  V G+ F ++ LRIE E
Sbjct: 198 PSVGFTLRDVSGGGEGRVT--FRVA---PEQGDLFDALHRRLGRVLGSEFAENALRIEGE 252

Query: 231 HQGLKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLF 290
            +GL+L G+   P  +R  +  Q+ +VNGR +RDKL+  A+R +Y   L  D+    VLF
Sbjct: 253 REGLRLSGYAALPTYSRGAAVAQFLFVNGRPVRDKLLVGALRGAYADFLSRDRHPAAVLF 312

Query: 291 IELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINE---GAFHL 347
           ++  P +VDVNVHPAK EVRF +  +    I  AL  AL +     + T+ +   GAF  
Sbjct: 313 VDCPPERVDVNVHPAKSEVRFREPGVARGLIVTALRHALAEAGHRASSTVADATLGAFRA 372

Query: 348 PHCAEEVNPPVVPMIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPW 407
           P                    R++Q                     D P       S  W
Sbjct: 373 PDA-------------VGSGARIYQ--------------------MDRPSAAALGRSTAW 399

Query: 408 VASPKTASTGKERYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAI 467
            A P+TA+ G   +G A                     E PS       ++EA+      
Sbjct: 400 QA-PETAAQG---FGFA---------------------EAPSARVEPAETVEAI-----A 429

Query: 468 EKLGKAIQVVAGQYLLMSSPQGCVLISLYQAQQL----KLRGLLNAQHGALKAQPLLVPL 523
             LG A   +   Y++  +  G VL+  + A +     +L+ L+ A++G + +Q LL+P 
Sbjct: 430 RPLGAARAQLHENYIVAQTETGMVLVDQHAAHERLVYERLKALM-AENG-VPSQALLIPE 487

Query: 524 ALKLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAA 583
            ++++E++ +     S  L  LG+ ++     ++ V   P  L     + LL D+L   +
Sbjct: 488 IVEMSEADARTLLDRSEELAALGLRIEPFGPGAVAVRETPALLGPVKAEALLRDILDELS 547

Query: 584 SCSESQAL 591
              ++ AL
Sbjct: 548 DLGQTDAL 555