Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 637 a.a., DNA mismatch repair protein mutL from Caulobacter crescentus NA1000

 Score =  258 bits (658), Expect = 8e-73
 Identities = 196/606 (32%), Positives = 296/606 (48%), Gaps = 44/606 (7%)

Query: 1   MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNG 60
           M IR LP    N+IAAGEVVERPAS +KELV+N++DAGATRI+++   GG   I + D+G
Sbjct: 1   MPIRRLPPETVNRIAAGEVVERPASAIKELVDNAIDAGATRIEVEAHGGGLTRILVADDG 60

Query: 61  SGIDKDELGLALSRHATSKI----HTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVA 116
            G+  +EL +A+ RHATSK+      L DL  I ++GFRGEAL SI SV+RL ++SR   
Sbjct: 61  CGLSPEELPVAIERHATSKLAPDADGLWDLLRIHTMGFRGEALPSIGSVARLQISSRAKG 120

Query: 117 QEEAWSAYSEGRDMAVKLQPAAH--PVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDEL 174
            ++A+S   EG  +  ++ PAA   P G  +EV DLF+ TPAR KF+++E+ E   I E 
Sbjct: 121 AKDAFSILVEGGQVG-EVAPAAFPGPHGARIEVRDLFYATPARLKFMKSERAEALAITEE 179

Query: 175 LKRIALSRFDVSFTLRHNGKIVRQYRAATTLPQ-QEKRLAAVCGNPFVQHMLRIELEHQG 233
           +KR A++   V F+L  +G+ V +       PQ +  RLAAV G  F ++ L I+    G
Sbjct: 180 IKRQAMANESVGFSLDIDGRRVLRLPPEHPGPQGRLARLAAVLGREFQENALEIDQTRDG 239

Query: 234 LKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIEL 293
           ++L G+   P   R  +  QY +VNGR +RD+L+  A+R +Y   L  D+  T  L++ L
Sbjct: 240 VRLSGFAGLPTYNRGNAAHQYLFVNGRPVRDRLLQGALRAAYADFLARDRHPTAALYVTL 299

Query: 294 DPHQVDVNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEE 353
           +  +VDVNVHPAK EVRF    LV   I  AL  AL       + T+   A       + 
Sbjct: 300 ETTEVDVNVHPAKAEVRFRDPALVRGLIVGALRHALAGAGHRASTTVAAQALDSIRAQQS 359

Query: 354 VNPPVVPMIDTTQQE---RVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVAS 410
             P   P             W+    TP  P + P        D P + E +        
Sbjct: 360 PFPGYQPQYQPGPSPAGFSAWREGGWTP--PTQRP-------MDLPGLNEVSARVEPSYG 410

Query: 411 PKTASTGKERYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKL 470
              A   +E Y +A+                   D  P+      +  + V        L
Sbjct: 411 GDLAGVVREAYAAAA-----------------FEDRPPTDYPGATAPFDPVD-----YPL 448

Query: 471 GKAIQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLNAQ--HGALKAQPLLVPLALKLN 528
           G A   V   Y++  +  G V++  + A +  +   +  +   G +  Q LL+P  + L+
Sbjct: 449 GAARAQVHETYIVAQTRDGMVIVDQHAAHERLVYERMKGEMASGGVTRQTLLLPEVVDLD 508

Query: 529 ESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSES 588
            +E +     +  L  LG+ L+S    +++V   P  L + +   L+ D+    A   ++
Sbjct: 509 PAEAERVVARAEELAGLGLVLESFGPGAVLVRETPALLGKTDAAALVRDIADDLAENGQA 568

Query: 589 QALSHQ 594
            AL  +
Sbjct: 569 LALKER 574